Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   VNN39_RS01380 Genome accession   NZ_CP141721
Coordinates   278552..279247 (-) Length   231 a.a.
NCBI ID   WP_017368870.1    Uniprot ID   A0A9Q8Y2F9
Organism   Lactococcus formosensis strain M04020401 EE5e5     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 273552..284247
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VNN39_RS01365 (VNN39_01365) - 274269..275006 (-) 738 WP_338997727.1 amino acid ABC transporter ATP-binding protein -
  VNN39_RS01370 (VNN39_01370) - 275007..276578 (-) 1572 WP_338997728.1 ABC transporter permease subunit -
  VNN39_RS01375 (VNN39_01375) covS 276974..278464 (-) 1491 WP_338997729.1 HAMP domain-containing histidine kinase Regulator
  VNN39_RS01380 (VNN39_01380) covR 278552..279247 (-) 696 WP_017368870.1 response regulator transcription factor Regulator
  VNN39_RS01385 (VNN39_01385) - 279348..279899 (-) 552 WP_165711405.1 YceD family protein -
  VNN39_RS01390 (VNN39_01390) - 280117..280359 (-) 243 WP_003135050.1 type B 50S ribosomal protein L31 -
  VNN39_RS01395 (VNN39_01395) - 280471..282375 (-) 1905 WP_338997730.1 fructose-specific PTS transporter subunit EIIC -
  VNN39_RS01400 (VNN39_01400) pfkB 282409..283326 (-) 918 WP_338997731.1 1-phosphofructokinase -
  VNN39_RS01405 (VNN39_01405) - 283323..284024 (-) 702 WP_338997732.1 DeoR/GlpR family DNA-binding transcription regulator -

Sequence

Protein


Download         Length: 231 a.a.        Molecular weight: 27023.75 Da        Isoelectric Point: 5.2713

>NTDB_id=918877 VNN39_RS01380 WP_017368870.1 278552..279247(-) (covR) [Lactococcus formosensis strain M04020401 EE5e5]
MNSSKRILIIEDDKNIARFVSLELEHEGYQTAVQDNGRKGLEEAMSKDYDLILLDLMLPELDGFEVARRLRREKDTHIIM
MTARDSTMDRVAGLDIGADDYITKPFAIEELLARVRSLFRREDHIHTVEKSDNTSFRDLVIDKTNRTVHRGKKVIDLTRR
EYDLLLTLMQNVGDVVTREYLVSEVWGYEEGTETNVVDVYIRYLRNKIDVEGRESYIQTVRGMGYVMRDRK

Nucleotide


Download         Length: 696 bp        

>NTDB_id=918877 VNN39_RS01380 WP_017368870.1 278552..279247(-) (covR) [Lactococcus formosensis strain M04020401 EE5e5]
ATGAATTCATCTAAACGTATTTTAATTATCGAGGACGATAAAAACATTGCGAGATTTGTTTCACTTGAGCTTGAACACGA
AGGGTATCAAACTGCGGTTCAAGACAATGGTCGTAAAGGTCTTGAAGAAGCGATGTCAAAAGATTATGATTTGATTTTGC
TTGACTTGATGCTCCCAGAGCTGGATGGCTTTGAAGTTGCACGACGCTTACGCCGTGAAAAAGATACACACATTATCATG
ATGACTGCACGTGATTCAACAATGGACCGTGTTGCTGGTCTTGATATTGGAGCGGATGATTATATTACAAAACCATTCGC
AATTGAAGAGTTGTTAGCACGTGTGCGTTCACTCTTCCGTCGTGAAGATCATATCCATACTGTTGAAAAGTCAGACAACA
CTTCATTCCGTGACTTGGTAATTGATAAAACAAACCGCACAGTACACCGTGGTAAAAAAGTCATTGACCTTACACGTCGT
GAGTACGACTTACTCTTGACTTTGATGCAAAATGTGGGGGACGTCGTAACACGCGAATACTTGGTTTCTGAAGTATGGGG
TTACGAAGAAGGTACAGAAACAAACGTTGTTGACGTTTATATCCGTTACCTACGTAACAAGATTGATGTCGAAGGCCGTG
AAAGTTATATCCAAACTGTTCGTGGCATGGGATATGTCATGCGTGACCGCAAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(7-116)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Lactococcus lactis subsp. lactis strain DGCC12653

88.646

99.134

0.879
  covR Streptococcus salivarius strain HSISS4

66.81

100

0.671
  vicR Streptococcus mutans UA159

43.723

100

0.437
  micA Streptococcus pneumoniae Cp1015

42.424

100

0.424