Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   VNN53_RS01350 Genome accession   NZ_CP141720
Coordinates   275279..275974 (-) Length   231 a.a.
NCBI ID   WP_004259096.1    Uniprot ID   -
Organism   Lactococcus garvieae strain CAHFS22OV20.5B5     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 270279..280974
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VNN53_RS01335 (VNN53_01335) - 270994..271731 (-) 738 WP_338962109.1 amino acid ABC transporter ATP-binding protein -
  VNN53_RS01340 (VNN53_01340) - 271732..273303 (-) 1572 WP_004259090.1 ABC transporter permease subunit -
  VNN53_RS01345 (VNN53_01345) covS 273700..275190 (-) 1491 WP_014024351.1 HAMP domain-containing histidine kinase Regulator
  VNN53_RS01350 (VNN53_01350) covR 275279..275974 (-) 696 WP_004259096.1 response regulator transcription factor Regulator
  VNN53_RS01355 (VNN53_01355) - 276076..276627 (-) 552 WP_023889673.1 DUF177 domain-containing protein -
  VNN53_RS01360 (VNN53_01360) - 276844..277086 (-) 243 WP_003135050.1 type B 50S ribosomal protein L31 -
  VNN53_RS01365 (VNN53_01365) - 277198..279102 (-) 1905 WP_014024348.1 fructose-specific PTS transporter subunit EIIC -
  VNN53_RS01370 (VNN53_01370) pfkB 279117..280043 (-) 927 WP_004259111.1 1-phosphofructokinase -
  VNN53_RS01375 (VNN53_01375) - 280040..280741 (-) 702 WP_004259114.1 DeoR/GlpR family DNA-binding transcription regulator -

Sequence

Protein


Download         Length: 231 a.a.        Molecular weight: 26979.74 Da        Isoelectric Point: 5.4730

>NTDB_id=918832 VNN53_RS01350 WP_004259096.1 275279..275974(-) (covR) [Lactococcus garvieae strain CAHFS22OV20.5B5]
MNSSKRILIIEDDKNIARFVSLELEHEGYQTAVQGNGRKGLEEAMSKDYDLILLDLMLPELDGFEVARRLRREKDTHIIM
MTARDSTMDRVAGLDIGADDYITKPFAIEELLARVRSLFRREDHIHTIEKSDNTSFRDLVIDKTNRTVHRGKKVIDLTRR
EYDLLLTLMQNVGDVVTREYLVSEVWGYEEGTETNVVDVYIRYLRNKIDVEGRESYIQTVRGMGYVMRDRK

Nucleotide


Download         Length: 696 bp        

>NTDB_id=918832 VNN53_RS01350 WP_004259096.1 275279..275974(-) (covR) [Lactococcus garvieae strain CAHFS22OV20.5B5]
ATGAATTCATCTAAACGTATTTTGATTATCGAAGACGATAAAAACATTGCGAGATTTGTTTCACTTGAGCTTGAACACGA
AGGCTACCAAACTGCGGTTCAAGGCAATGGTCGTAAAGGTCTTGAAGAAGCAATGTCAAAAGATTATGATTTGATTTTGC
TTGACCTAATGCTCCCAGAGCTTGATGGCTTTGAAGTTGCACGACGCTTACGCCGTGAGAAAGATACACATATTATTATG
ATGACTGCACGTGATTCGACAATGGACCGTGTAGCAGGTCTTGATATTGGCGCAGATGACTATATTACAAAACCATTTGC
TATTGAAGAATTGTTAGCGCGTGTCCGCTCACTCTTCCGTCGTGAAGATCATATCCACACGATTGAAAAGTCAGACAATA
CTTCATTCCGTGATTTGGTAATTGATAAGACCAACCGTACTGTACACCGTGGAAAAAAAGTTATTGACCTTACACGCCGT
GAGTACGATTTGCTTTTGACACTGATGCAAAATGTAGGTGATGTCGTAACACGTGAATACTTGGTTTCTGAAGTATGGGG
CTACGAAGAAGGTACAGAAACAAACGTTGTGGACGTTTATATCCGTTATCTGCGTAACAAAATTGACGTGGAGGGCCGTG
AAAGCTATATCCAAACGGTTCGTGGTATGGGATATGTCATGCGTGACCGCAAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-227)

Response regulator receiver domain (Response_reg)

(7-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Lactococcus lactis subsp. lactis strain DGCC12653

87.773

99.134

0.87
  covR Streptococcus salivarius strain HSISS4

66.81

100

0.671
  vicR Streptococcus mutans UA159

43.723

100

0.437
  micA Streptococcus pneumoniae Cp1015

42.424

100

0.424