Detailed information NTG0918592

Bioinformatically predicted

Overview

• Name: comEC
• Type: Machinery gene
• Locus tag: VNN32_RS06470
• Genome accession: NZ_CP141703
• Coordinates: 1220076..1222286 (+)
• Length: 736 a.a.
• NCBI ID: WP_046400802.1
• Uniprot ID: -
• Organism: Lactococcus petauri strain R21-74 AL-1
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1215076..1227286

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
VNN32_RS06450 (VNN32_06445)	-	1215667..1216311 (+)	645	WP_019292099.1	CPBP family intramembrane glutamic endopeptidase	-
VNN32_RS06455 (VNN32_06450)	-	1216458..1218014 (+)	1557	WP_019292098.1	ATP-binding cassette domain-containing protein	-
VNN32_RS06460 (VNN32_06455)	-	1218179..1219354 (+)	1176	WP_019292097.1	SLC13 family permease	-
VNN32_RS06465 (VNN32_06460)	-	1219412..1220056 (+)	645	WP_046400803.1	helix-hairpin-helix domain-containing protein	-
VNN32_RS06470 (VNN32_06465)	comEC	1220076..1222286 (+)	2211	WP_046400802.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
VNN32_RS06475 (VNN32_06470)	-	1222441..1223217 (+)	777	WP_029343492.1	alpha/beta hydrolase family protein	-
VNN32_RS06480 (VNN32_06475)	-	1223413..1223628 (+)	216	WP_003135074.1	F0F1 ATP synthase subunit C	-
VNN32_RS06485 (VNN32_06480)	atpB	1223683..1224396 (+)	714	WP_004259176.1	F0F1 ATP synthase subunit A	-
VNN32_RS06490 (VNN32_06485)	atpF	1224410..1224916 (+)	507	WP_004259173.1	F0F1 ATP synthase subunit B	-
VNN32_RS06495 (VNN32_06490)	-	1224931..1225458 (+)	528	WP_019292093.1	F0F1 ATP synthase subunit delta	-
VNN32_RS06500 (VNN32_06495)	atpA	1225524..1227032 (+)	1509	WP_046400801.1	F0F1 ATP synthase subunit alpha	-

Sequence

Protein

• Length: 736 a.a.
• Molecular weight: 85138.11 Da
• Isoelectric Point: 9.7729

>NTDB_id=918592 VNN32_RS06470 WP_046400802.1 1220076..1222286(+) (comEC) [Lactococcus petauri strain R21-74 AL-1]
MKQKFTLIYLVYLLVFVYFLIFSFSWPLLILSLFSLFIAFYRQYYSLLALLLCFSFFLLMVKKETEVQEIQQPEKISKIT
PYMDTLQVNGNRLSFRGEVNGRDFQAFYTLTSEKEKEYFKNLRIKGIFYIEGTLDIPEEQRNFSSFDYRKYLRTQGIYRL
LKIEKIEGFEEKHDFDLRLVRRKAILWTQEHFPSPMSSYMTGLLFGWLDKDFEEMGELYTSLGIIHLFALSGMQVNFFIE
LLRNILLRLGLSRKLVYFIQIPFSIFYAFLTGLSLSILRALLQKNIPIKNSSDRFSITFLLLMIFSPYFLLTTGGQLTML
YSFLITFFSQKFNELKGLKRALLDSTVLAVGVLPLLIFQFHSFQPLSIILTLLFSLIFDFLLLPGLLFVFLLSLVGIDLT
LLNPFFIILESIVRLVGSLFDKPIVFGKPNLIFLLLLFMLSGLALDFYRKRNWNLVVIIVLFFLFFLVKNPKHPSITMVD
VGQGDSILLQDRWNSQNILIDTGGRLKIRADEQWKEGIYKSNAESTLLPYLRASGVSKVDVLIVTHPDEDHIGDLESVAQ
KVPIKNIYVSASALEKKNFVKKLSSLKSQIHIVQEGDKLPIFNSYLRFLTTGGEGKSDNDNSLVTFGEFYGKKFLFTGDL
EEEGEVKLQKEYPHLEVDILKVGHHGSKTSTKEGFLEAIKPKVALISAGKNNRYKHPSQETLHQLTARGIKIYRTDQQGA
IRFLYKKGTWQIQTVK

Nucleotide

• Length: 2211 bp

>NTDB_id=918592 VNN32_RS06470 WP_046400802.1 1220076..1222286(+) (comEC) [Lactococcus petauri strain R21-74 AL-1]
ATGAAACAAAAATTTACGCTTATCTATTTAGTCTATCTCTTAGTTTTTGTTTATTTTCTTATTTTCAGTTTTTCATGGCC
TTTACTTATTCTTAGTTTGTTTAGTCTCTTCATCGCTTTTTATCGTCAATACTATAGTTTGTTAGCTCTTTTACTGTGCT
TTAGTTTCTTCTTACTCATGGTAAAAAAAGAGACAGAAGTACAAGAAATACAACAACCAGAAAAAATTTCGAAGATTACC
CCTTATATGGATACTCTTCAAGTGAATGGAAATAGGCTCAGTTTCAGGGGAGAAGTGAACGGAAGAGATTTTCAAGCTTT
TTACACATTGACTTCGGAAAAAGAAAAAGAATACTTTAAAAATCTTAGGATAAAGGGGATTTTTTACATTGAAGGCACTT
TAGATATCCCAGAAGAGCAAAGAAACTTTTCAAGTTTTGATTACAGAAAGTATTTAAGAACGCAAGGTATTTACCGACTT
CTTAAAATAGAAAAAATTGAAGGATTTGAAGAAAAACATGACTTTGATTTACGGCTGGTACGCCGAAAAGCCATTCTTTG
GACACAAGAACATTTTCCTTCTCCCATGTCGTCCTATATGACAGGGCTTCTTTTTGGTTGGTTGGATAAAGACTTTGAAG
AAATGGGGGAGCTTTATACTAGCCTCGGTATTATCCATTTATTTGCCCTGTCAGGGATGCAGGTGAATTTTTTTATTGAA
CTTCTTCGAAATATTTTATTAAGGCTAGGTTTATCAAGAAAGTTGGTCTATTTTATCCAAATTCCCTTTTCGATATTTTA
TGCTTTTCTTACTGGCTTATCTCTCTCAATCTTACGTGCGCTTCTTCAAAAAAATATACCTATTAAAAATTCAAGCGATA
GATTTTCTATCACTTTTCTTCTTTTAATGATATTCAGTCCATATTTCCTACTGACAACAGGAGGACAACTGACGATGCTC
TATTCTTTCTTAATCACATTTTTTTCACAAAAATTCAATGAACTAAAAGGATTAAAAAGAGCATTACTTGATTCTACTGT
TCTAGCTGTTGGGGTACTTCCGCTTTTGATTTTTCAATTCCATTCTTTCCAACCATTATCGATTATATTGACTTTATTAT
TTAGTCTGATTTTTGATTTTTTACTTTTGCCAGGTTTACTTTTTGTCTTTCTCCTTTCTTTAGTCGGCATTGATCTTACA
TTACTTAATCCTTTTTTTATTATTTTAGAATCAATAGTAAGACTGGTTGGCAGTTTATTTGATAAACCGATTGTATTTGG
CAAACCAAATCTTATTTTTTTACTTTTGCTTTTTATGCTAAGTGGACTTGCACTCGATTTTTACAGAAAAAGAAACTGGA
ACTTAGTTGTAATAATTGTTCTTTTCTTTCTTTTTTTCCTTGTTAAGAATCCTAAACACCCAAGCATTACAATGGTAGAT
GTGGGCCAAGGAGACAGTATTCTCTTGCAAGACAGGTGGAACAGTCAAAATATCTTAATTGATACTGGCGGTAGATTAAA
AATAAGAGCTGATGAGCAGTGGAAGGAGGGAATTTATAAGAGCAATGCTGAAAGTACACTTCTACCTTATCTGAGAGCGA
GTGGAGTGAGCAAAGTAGATGTTCTGATTGTGACACATCCAGATGAGGATCATATTGGTGACTTGGAGAGTGTAGCTCAG
AAAGTACCAATAAAAAATATTTATGTCTCAGCTAGTGCATTAGAGAAGAAAAATTTTGTTAAAAAACTAAGCAGCTTAAA
AAGTCAGATTCACATTGTGCAAGAGGGAGACAAGCTCCCCATATTTAACAGTTATCTCCGGTTTCTAACGACAGGAGGTG
AAGGAAAAAGCGATAATGATAATTCTTTAGTAACGTTTGGTGAATTTTATGGGAAGAAATTTCTTTTTACAGGTGACTTA
GAAGAAGAGGGAGAGGTTAAACTCCAGAAAGAATATCCACATTTAGAGGTTGATATCCTAAAAGTTGGACATCATGGCAG
TAAGACTTCTACAAAGGAAGGTTTTTTAGAAGCGATTAAGCCTAAGGTTGCTCTTATTTCTGCTGGAAAGAATAATCGAT
ATAAACATCCGAGTCAAGAAACGCTTCACCAATTAACTGCACGAGGAATAAAAATTTATCGGACAGACCAGCAAGGAGCA
ATCCGTTTCCTTTATAAAAAAGGCACTTGGCAAATTCAAACAGTAAAGTAA

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (481-689)

• Competence protein (Competence) (203-445)

• Domain of unknown function (DUF4131) (DUF4131) (23-167)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC	Lactococcus lactis subsp. cremoris KW2	52.66	99.592	0.524
comEC/celB	Streptococcus mitis SK321	45.101	100	0.457
comEC/celB	Streptococcus pneumoniae TIGR4	43.876	100	0.443
comEC/celB	Streptococcus mitis NCTC 12261	43.801	100	0.442
comEC/celB	Streptococcus pneumoniae Rx1	43.472	100	0.439
comEC/celB	Streptococcus pneumoniae D39	43.472	100	0.439
comEC/celB	Streptococcus pneumoniae R6	43.472	100	0.439