Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   VNN27_RS01360 Genome accession   NZ_CP141700
Coordinates   276157..276852 (-) Length   231 a.a.
NCBI ID   WP_019292077.1    Uniprot ID   A0A139ME49
Organism   Lactococcus petauri strain R22-25 IC35     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 271157..281852
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VNN27_RS01345 (VNN27_01345) - 271874..272611 (-) 738 WP_019292074.1 amino acid ABC transporter ATP-binding protein -
  VNN27_RS01350 (VNN27_01350) - 272612..274183 (-) 1572 WP_195916740.1 ABC transporter permease subunit -
  VNN27_RS01355 (VNN27_01355) covS 274579..276069 (-) 1491 WP_019293246.1 HAMP domain-containing histidine kinase Regulator
  VNN27_RS01360 (VNN27_01360) covR 276157..276852 (-) 696 WP_019292077.1 response regulator transcription factor Regulator
  VNN27_RS01365 (VNN27_01365) - 276954..277505 (-) 552 WP_346350078.1 YceD family protein -
  VNN27_RS01370 (VNN27_01370) - 277722..277964 (-) 243 WP_003135050.1 type B 50S ribosomal protein L31 -
  VNN27_RS01375 (VNN27_01375) - 278076..279980 (-) 1905 WP_019292079.1 fructose-specific PTS transporter subunit EIIC -
  VNN27_RS01380 (VNN27_01380) pfkB 279995..280921 (-) 927 WP_346350079.1 1-phosphofructokinase -
  VNN27_RS01385 (VNN27_01385) - 280918..281619 (-) 702 WP_019292081.1 DeoR/GlpR family DNA-binding transcription regulator -

Sequence

Protein


Download         Length: 231 a.a.        Molecular weight: 27037.77 Da        Isoelectric Point: 5.2713

>NTDB_id=918475 VNN27_RS01360 WP_019292077.1 276157..276852(-) (covR) [Lactococcus petauri strain R22-25 IC35]
MNSSKRILIIEDDKNIARFVSLELEHEGYQTAVQDNGRKGLEEAMSKDYDLILLDLMLPELDGFEVARRLRREKDTHIIM
MTARDSTMDRVAGLDIGADDYITKPFAIEELLARVRSLFRREDHIHTIEKSDNTSFRDLVIDKTNRTVHRGKKVIDLTRR
EYDLLLTLMQNVGDVVTREYLVSEVWGYEEGTETNVVDVYIRYLRNKIDVEGRESYIQTVRGMGYVMRDRK

Nucleotide


Download         Length: 696 bp        

>NTDB_id=918475 VNN27_RS01360 WP_019292077.1 276157..276852(-) (covR) [Lactococcus petauri strain R22-25 IC35]
ATGAATTCATCTAAACGTATTTTGATTATCGAAGACGATAAAAACATTGCGAGATTTGTTTCACTTGAGCTTGAACACGA
AGGATATCAAACTGCGGTTCAAGACAATGGTCGTAAAGGTCTTGAAGAAGCAATGTCAAAAGATTATGATTTGATTTTGC
TCGACTTAATGCTCCCAGAGCTGGATGGCTTTGAAGTTGCACGACGCTTACGCCGTGAAAAAGATACACATATTATTATG
ATGACTGCACGTGATTCAACAATGGACCGTGTAGCAGGTCTTGATATTGGAGCGGATGACTATATTACAAAACCATTCGC
AATTGAAGAATTGTTAGCGCGTGTCCGTTCACTCTTCCGTCGTGAAGACCATATCCACACGATTGAAAAATCAGACAATA
CTTCATTCCGTGATTTGGTAATTGATAAAACAAACCGCACTGTACATCGTGGAAAAAAAGTTATTGACCTTACACGTCGT
GAATACGATTTGCTTTTGACCCTGATGCAAAATGTGGGTGACGTCGTAACACGCGAATACTTGGTTTCTGAAGTATGGGG
TTACGAAGAAGGTACAGAAACAAACGTTGTTGACGTTTATATCCGCTATTTGCGTAACAAAATTGACGTGGAAGGCCGCG
AAAGTTATATTCAAACGGTTCGTGGTATGGGATATGTCATGCGTGACCGCAAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-227)

Response regulator receiver domain (Response_reg)

(7-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A139ME49

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Lactococcus lactis subsp. lactis strain DGCC12653

88.21

99.134

0.874
  covR Streptococcus salivarius strain HSISS4

67.241

100

0.675
  vicR Streptococcus mutans UA159

43.723

100

0.437
  micA Streptococcus pneumoniae Cp1015

42.424

100

0.424