Detailed information NTG0918432

Bioinformatically predicted

Overview

• Name: comEC
• Type: Machinery gene
• Locus tag: VNN49_RS01440
• Genome accession: NZ_CP141699
• Coordinates: 286105..288315 (-)
• Length: 736 a.a.
• NCBI ID: WP_019293626.1
• Uniprot ID: -
• Organism: Lactococcus petauri strain M17100408 FF4i7
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 281105..293315

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
VNN49_RS01410 (VNN49_01410)	atpA	281359..282867 (-)	1509	WP_004259170.1	F0F1 ATP synthase subunit alpha	-
VNN49_RS01415 (VNN49_01415)	-	282933..283460 (-)	528	WP_019292093.1	F0F1 ATP synthase subunit delta	-
VNN49_RS01420 (VNN49_01420)	atpF	283475..283981 (-)	507	WP_004259173.1	F0F1 ATP synthase subunit B	-
VNN49_RS01425 (VNN49_01425)	atpB	283995..284708 (-)	714	WP_019293624.1	F0F1 ATP synthase subunit A	-
VNN49_RS01430 (VNN49_01430)	-	284763..284978 (-)	216	WP_003135074.1	F0F1 ATP synthase subunit C	-
VNN49_RS01435 (VNN49_01435)	-	285174..285950 (-)	777	WP_338963486.1	alpha/beta hydrolase family protein	-
VNN49_RS01440 (VNN49_01440)	comEC	286105..288315 (-)	2211	WP_019293626.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
VNN49_RS01445 (VNN49_01445)	-	288335..288979 (-)	645	WP_019293627.1	helix-hairpin-helix domain-containing protein	-
VNN49_RS01450 (VNN49_01450)	-	289037..290212 (-)	1176	WP_019292097.1	SLC13 family permease	-
VNN49_RS01455 (VNN49_01455)	-	290378..291934 (-)	1557	WP_019292098.1	ATP-binding cassette domain-containing protein	-
VNN49_RS01460 (VNN49_01460)	-	292081..292725 (-)	645	WP_019293598.1	CPBP family intramembrane glutamic endopeptidase	-

Sequence

Protein

• Length: 736 a.a.
• Molecular weight: 85118.04 Da
• Isoelectric Point: 9.7859

>NTDB_id=918432 VNN49_RS01440 WP_019293626.1 286105..288315(-) (comEC) [Lactococcus petauri strain M17100408 FF4i7]
MKQKFTLIYLVYLLVFVYFLIFSFSWPLLILSLFSLFIAFYRQYYSLLALLLCFSFFLLMVKKETEVQEIQQPEKISKIT
PYMDTLQVNGNRLSFRGEVNGRDFQAFYTLTSEKEKEYFKNLRIKGIFYIEGTLEIPEEQRNFSGFDYRKYLRTQGISRL
LKIEKIEGFEEKHDFDLRLVRRKAILWTQEHFPSPMSSYMTGLLFGWLDKDFEEMGELYTSLGIIHLFALSGMQVNFFIE
LLRNILLRLGLSRKLVYFIQIPFSIFYAFLTGLSLSILRALLQKNIPIKNSSDRFSITFLLLMIFSPYFLLTTGGQLTML
YSFLITFFSQKFNELKGLKRALLDSTVLAVGVLPLLIFHFHSFQPLSIILTLLFSLIFDFLLLPGLLFVFLLSLFGIDLT
LLNPFFIILESIVRLVGSLFDKPIVFGKPNLIFLLLLFMLSGLALDFYRKRNWNLVVIIVLFFLFFLVKNPKHPNITMVD
VGQGDSILLQDRWNSQNILIDTGGRLKIRADEQWKEGIYKSNAESTLLPYLRASGVSKVDVLIVTHPDEDHIGDLESVAQ
KVPIKNIYVSASALEKKNFVKKLSSLKSQIHIVQEGDKLPIFNSYLRFLTTGGEGKSDNDNSLVTFGEFYGKKFLFTGDL
EEEGEVKLQKEYPHLEVDILKVGHHGSKTSTKEGFLEAIKPKVALISAGKNNRYKHPSQETLHQLTARGIKIYRTDQQGA
TRFLYKKGTWQIQTVK

Nucleotide

• Length: 2211 bp

>NTDB_id=918432 VNN49_RS01440 WP_019293626.1 286105..288315(-) (comEC) [Lactococcus petauri strain M17100408 FF4i7]
ATGAAACAAAAATTTACGCTTATCTATTTAGTATATCTCTTAGTTTTTGTTTATTTTCTTATTTTCAGTTTTTCATGGCC
TTTACTTATTCTTAGTTTGTTTAGTCTCTTCATCGCTTTTTATCGTCAATACTATAGTTTGTTAGCCCTTTTACTGTGCT
TTAGTTTCTTCTTACTCATGGTAAAAAAAGAGACAGAAGTACAGGAAATACAACAACCAGAAAAAATTTCGAAGATTACC
CCTTATATGGATACTCTTCAAGTGAATGGAAACAGACTCAGTTTCAGGGGAGAAGTGAACGGAAGAGATTTCCAAGCTTT
TTACACATTGACTTCGGAAAAAGAAAAAGAATACTTTAAAAATCTTAGGATAAAGGGGATTTTTTACATTGAAGGCACAT
TAGAGATACCAGAAGAGCAAAGAAACTTTTCAGGTTTTGATTACAGAAAGTATTTAAGGACGCAAGGTATTTCCCGACTT
CTTAAAATAGAAAAAATTGAAGGATTTGAAGAAAAACATGACTTTGATTTACGGCTGGTACGCCGAAAAGCTATTCTTTG
GACACAAGAACATTTTCCTTCTCCCATGTCGTCCTATATGACAGGGCTTCTTTTTGGTTGGTTGGATAAAGACTTTGAAG
AAATGGGGGAACTTTATACTAGCCTCGGTATTATCCATTTATTTGCCCTGTCAGGGATGCAGGTAAATTTTTTTATTGAA
CTTCTTCGAAATATTTTATTAAGGCTAGGTTTATCAAGAAAGTTGGTCTATTTTATCCAAATTCCCTTTTCGATATTTTA
TGCTTTTCTTACTGGCTTATCTCTCTCAATCTTACGTGCGCTTCTTCAAAAAAATATACCTATTAAAAATTCAAGCGATA
GATTTTCTATCACTTTTCTTCTTTTAATGATATTCAGTCCATATTTCCTACTGACAACAGGAGGACAACTGACGATGCTC
TATTCTTTCTTAATCACATTTTTTTCACAAAAATTCAATGAACTAAAAGGATTAAAAAGAGCATTACTTGATTCTACTGT
TCTAGCTGTTGGGGTACTTCCGCTTTTGATTTTTCACTTCCATTCTTTCCAACCATTATCGATTATATTGACTTTATTAT
TTAGTCTGATTTTTGATTTTTTACTTTTGCCTGGTTTACTTTTTGTCTTTCTCCTTTCTTTATTCGGCATTGATCTTACA
TTACTTAATCCTTTTTTTATTATTTTAGAATCAATAGTAAGACTGGTTGGCAGTTTATTTGATAAACCGATTGTATTTGG
CAAACCAAATCTTATTTTTTTACTTTTGCTTTTTATGCTAAGTGGACTTGCACTCGATTTTTACAGAAAAAGGAACTGGA
ACTTAGTTGTAATAATTGTCCTTTTCTTTCTTTTTTTCCTTGTTAAAAATCCTAAACACCCAAATATTACAATGGTAGAT
GTGGGCCAAGGAGACAGCATTCTCTTGCAAGACAGGTGGAACAGTCAAAATATCTTAATTGATACTGGCGGTAGATTAAA
AATAAGAGCTGATGAGCAGTGGAAGGAGGGAATTTATAAGAGCAATGCTGAAAGTACACTTCTACCTTATCTGAGAGCGA
GTGGAGTGAGCAAAGTAGATGTTCTGATTGTGACACATCCAGATGAGGATCATATTGGCGACTTGGAGAGTGTAGCTCAG
AAAGTACCAATAAAAAATATTTATGTATCAGCTAGTGCATTAGAGAAGAAAAATTTTGTTAAAAAACTAAGCAGCTTAAA
AAGTCAGATTCACATTGTGCAAGAGGGAGACAAGCTCCCCATATTTAACAGTTATCTCCGGTTTCTAACGACAGGAGGTG
AAGGAAAAAGCGATAATGATAATTCTTTAGTGACGTTTGGTGAATTTTATGGGAAGAAATTTCTTTTTACAGGTGACTTA
GAAGAAGAGGGAGAGGTTAAACTCCAGAAAGAATATCCACATTTAGAAGTTGATATCCTAAAAGTTGGACATCATGGCAG
TAAGACTTCTACAAAGGAAGGTTTTTTAGAAGCGATTAAGCCTAAGGTTGCTCTTATTTCTGCTGGAAAGAATAATCGAT
ATAAACATCCGAGTCAAGAAACGCTTCACCAATTAACTGCACGAGGAATAAAAATTTATCGGACAGACCAGCAAGGAGCA
ACCCGTTTCCTTTATAAAAAAGGCACTTGGCAAATTCAAACAGTAAAGTAA

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (481-689)

• Domain of unknown function (DUF4131) (DUF4131) (23-167)

• Competence protein (Competence) (203-445)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC	Lactococcus lactis subsp. cremoris KW2	52.387	99.592	0.522
comEC/celB	Streptococcus mitis SK321	45.101	100	0.457
comEC/celB	Streptococcus pneumoniae TIGR4	43.876	100	0.443
comEC/celB	Streptococcus mitis NCTC 12261	43.801	100	0.442
comEC/celB	Streptococcus pneumoniae Rx1	43.472	100	0.439
comEC/celB	Streptococcus pneumoniae D39	43.472	100	0.439
comEC/celB	Streptococcus pneumoniae R6	43.472	100	0.439