Detailed information    

insolico Bioinformatically predicted

Overview

Name   comC   Type   Machinery gene
Locus tag   U2H22_RS14250 Genome accession   NZ_CP141265
Coordinates   2833806..2834558 (-) Length   250 a.a.
NCBI ID   WP_012118107.1    Uniprot ID   A7Z796
Organism   Bacillus velezensis strain L2D39     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2828806..2839558
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U2H22_RS14225 (U2H22_14225) mreC 2829242..2830105 (-) 864 WP_007408166.1 rod shape-determining protein MreC -
  U2H22_RS14230 (U2H22_14230) mreB 2830136..2831149 (-) 1014 WP_003152647.1 cell shape-determining protein MreB -
  U2H22_RS14235 (U2H22_14235) radC 2831241..2831936 (-) 696 WP_007408165.1 DNA repair protein RadC -
  U2H22_RS14240 (U2H22_14240) - 2831968..2832537 (-) 570 WP_218791307.1 Maf family protein -
  U2H22_RS14245 (U2H22_14245) - 2832678..2833679 (-) 1002 WP_061860762.1 SPOR domain-containing protein -
  U2H22_RS14250 (U2H22_14250) comC 2833806..2834558 (-) 753 WP_012118107.1 A24 family peptidase Machinery gene
  U2H22_RS14255 (U2H22_14255) - 2834698..2835990 (-) 1293 WP_218791308.1 folylpolyglutamate synthase/dihydrofolate synthase family protein -
  U2H22_RS14260 (U2H22_14260) - 2836049..2838691 (-) 2643 WP_015417930.1 valine--tRNA ligase -
  U2H22_RS14265 (U2H22_14265) - 2839144..2839335 (+) 192 WP_003152639.1 hypothetical protein -

Sequence

Protein


Download         Length: 250 a.a.        Molecular weight: 27219.94 Da        Isoelectric Point: 9.4293

>NTDB_id=916679 U2H22_RS14250 WP_012118107.1 2833806..2834558(-) (comC) [Bacillus velezensis strain L2D39]
MLLILFFLGLIFGSFFYTAACRIPLRISVISPRSACSFCRLPLSWGELVPVVSYILQRGRCRNCRAKLSVMYPAAECWTA
CLFTAAGIHFGFSKELLVALLFLSLLMIVTMTDLQYMLIPDKVLLFFLPLFIAGRMFSPLDSWYAGFAGAVCGFFLLVFI
MFVSKGGIGAGDVKLFGVIGLTLGVKLVLIAFFLSVMIGAVYGMCAAARGRLGKKQPFPFAPAISAGSALSYLYGEELFS
FYIKLASGGA

Nucleotide


Download         Length: 753 bp        

>NTDB_id=916679 U2H22_RS14250 WP_012118107.1 2833806..2834558(-) (comC) [Bacillus velezensis strain L2D39]
GTGCTTTTGATTCTGTTTTTTCTCGGCTTGATTTTCGGTTCTTTTTTTTATACAGCAGCGTGCCGTATCCCGCTGCGAAT
CTCGGTTATTTCGCCGCGTTCAGCCTGTTCGTTTTGCCGCTTGCCGCTCTCCTGGGGGGAGCTTGTGCCCGTCGTTTCCT
ATATTCTGCAAAGAGGCAGATGCAGAAACTGCCGTGCGAAGCTGTCGGTTATGTATCCGGCGGCGGAATGCTGGACGGCA
TGTTTATTCACGGCTGCAGGCATTCATTTCGGTTTCTCAAAAGAACTGTTAGTCGCGCTGTTATTTCTGTCTCTGCTCAT
GATTGTTACTATGACGGATCTGCAATATATGCTGATTCCTGACAAGGTTCTGCTGTTTTTTCTTCCGCTTTTCATCGCCG
GCCGTATGTTTTCTCCGCTGGATTCATGGTATGCAGGGTTTGCCGGAGCCGTTTGCGGATTTTTTCTGCTTGTTTTTATC
ATGTTTGTCAGTAAAGGAGGCATCGGCGCAGGTGATGTGAAACTGTTTGGGGTGATCGGCCTGACGCTCGGCGTGAAGCT
CGTGCTCATTGCATTCTTTCTCTCCGTTATGATCGGAGCCGTATACGGTATGTGCGCCGCAGCCCGGGGCAGGCTTGGTA
AAAAGCAGCCATTTCCGTTTGCGCCGGCCATCTCAGCCGGGAGCGCTTTGAGTTATTTATACGGTGAAGAGCTGTTTTCG
TTTTACATCAAGCTCGCTTCAGGCGGGGCTTGA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-90)

Type IV leader peptidase family (Peptidase_A24)

(101-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A7Z796

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comC Bacillus subtilis subsp. subtilis str. 168

58.871

99.2

0.584