Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC/celB   Type   Machinery gene
Locus tag   U0N78_RS07960 Genome accession   NZ_CP140109
Coordinates   1674620..1676857 (-) Length   745 a.a.
NCBI ID   WP_174850284.1    Uniprot ID   -
Organism   Streptococcus suis strain 2022WUSS148     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1669620..1681857
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U0N78_RS07960 (U0N78_07960) comEC/celB 1674620..1676857 (-) 2238 WP_174850284.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  U0N78_RS07965 (U0N78_07965) - 1676841..1677503 (-) 663 WP_172097433.1 helix-hairpin-helix domain-containing protein -
  U0N78_RS07970 (U0N78_07970) - 1677570..1678316 (-) 747 WP_043026932.1 lysophospholipid acyltransferase family protein -
  U0N78_RS07975 (U0N78_07975) - 1678465..1679910 (+) 1446 WP_043026933.1 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase -
  U0N78_RS07980 (U0N78_07980) - 1680376..1681161 (+) 786 WP_014636900.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 745 a.a.        Molecular weight: 84016.75 Da        Isoelectric Point: 6.8709

>NTDB_id=912589 U0N78_RS07960 WP_174850284.1 1674620..1676857(-) (comEC/celB) [Streptococcus suis strain 2022WUSS148]
MSRSIKLPCQPIHLAVLAVAAYFAVHSFSLLTMGLLSLLLVVFGVRQGKTVFLKTLPLLALCGLFFSYQKVQWERADQSA
PEQVATVQVIPDTIDINGDNLSFRGRADGQTYQVFYKLASQEEQTYFQKLTDLVQLEVEAEVSLPAGQRNFNGFDYQAYL
KTQGIYRTVKISAIKKIVPIQSWNVFDLLSSWRRQALVYIKTNFPAPMSHYMTGLLFGELDSDFDQMSDLYSSLGIIHLF
ALSGMQVGFFIDKFRWILLRLGLTKEAVDKLQIPFSIVYAGLTGFSVSVVRSLVQKILGNLGLRKLDNFAVTVFVCLLIL
PRFLLTAGGVLTFTYAFLLTVFDFEDLGQVKKAAVESLSISLGILPVLMTYFYAFQPLSILLTFVFSFIFDVLLLPGLSV
IFLLSPVVKMTWVNGFFVFMEKIIVWVADLGFRPWILGKPSELVLLLLLVSLFLLYDFHRRKKWLLGLSLVLALLFFITK
YPLENEVTVVDIGQGDSIFLRDMRGRTVLIDVGGRVDFAAKEEWQERSSQANAERTLIPYLHSRGVDRIDSLVLTHTDTD
HVGDVLEVAKQVQIGRIYVSPGSLTVPDFVATLKEINVPVHVVAVGDRLPIFDSYLEVLYPSGTGDGGNNDSVVLYGRLL
ETNFLFTGDLEQGELDLIKTYPNLPVDVLKAGHHGSKGSSYPEFLDHIGAKIALVSAGENNRYKHPHQETLERFDNRNIQ
VYRTDQQGAIRFRGWREWRIETVRE

Nucleotide


Download         Length: 2238 bp        

>NTDB_id=912589 U0N78_RS07960 WP_174850284.1 1674620..1676857(-) (comEC/celB) [Streptococcus suis strain 2022WUSS148]
ATGTCACGGTCGATTAAGCTCCCCTGCCAGCCCATTCACCTGGCAGTATTGGCGGTGGCGGCCTACTTTGCAGTCCACTC
TTTTTCCCTCTTGACAATGGGCCTGCTGAGTCTGTTACTAGTTGTCTTTGGTGTTCGGCAAGGTAAGACAGTTTTCCTCA
AAACGCTGCCGCTTCTAGCCCTATGTGGTCTGTTTTTCAGCTACCAAAAGGTCCAATGGGAGCGGGCAGACCAGTCAGCC
CCTGAGCAAGTGGCGACTGTGCAGGTCATTCCAGATACTATTGATATTAATGGCGACAATCTGTCTTTTCGTGGTCGGGC
TGACGGACAAACCTATCAGGTTTTCTACAAATTAGCTAGTCAGGAGGAGCAGACTTATTTTCAAAAGCTAACAGATTTGG
TCCAGCTTGAAGTGGAAGCAGAGGTCAGCCTGCCAGCTGGTCAGCGGAATTTCAACGGCTTTGACTACCAAGCCTATCTG
AAAACGCAGGGAATTTATCGGACAGTTAAGATTTCTGCGATTAAGAAGATTGTCCCTATCCAGTCTTGGAATGTTTTTGA
CTTGCTATCAAGCTGGCGGAGGCAGGCCTTGGTCTATATCAAAACCAATTTTCCAGCACCCATGAGCCACTACATGACAG
GGCTTTTGTTTGGGGAGCTGGATAGTGATTTTGATCAGATGAGTGACCTCTATTCCAGTCTGGGTATCATTCATCTTTTC
GCCCTGTCTGGCATGCAGGTTGGATTTTTCATCGACAAGTTTCGCTGGATTTTACTGCGTTTGGGCTTGACCAAGGAAGC
CGTAGATAAGTTACAAATTCCCTTTTCCATTGTTTATGCTGGTTTGACAGGCTTTTCGGTGTCGGTGGTGCGGTCTTTGG
TTCAGAAAATATTGGGCAATTTGGGCTTGCGGAAGTTGGATAACTTTGCGGTGACAGTCTTTGTCTGTCTGCTGATTCTG
CCCCGATTTTTGCTGACAGCTGGTGGTGTCCTGACCTTTACCTATGCTTTCTTGCTGACAGTTTTTGATTTTGAAGACTT
GGGGCAGGTCAAAAAGGCTGCGGTGGAGAGCCTCAGTATTTCGCTGGGGATTTTACCGGTGCTCATGACCTATTTCTATG
CCTTTCAGCCCCTGTCCATTCTCCTGACCTTTGTCTTTTCCTTTATTTTTGATGTCCTGCTCTTGCCAGGTTTGTCGGTC
ATTTTTCTTTTGTCGCCAGTTGTCAAGATGACTTGGGTCAACGGATTTTTTGTCTTTATGGAGAAGATTATTGTCTGGGT
GGCTGACTTGGGTTTCAGACCTTGGATACTGGGCAAGCCGTCTGAGCTGGTCCTCTTGCTTTTGCTGGTCAGCCTCTTCT
TGCTCTACGATTTCCACAGGAGAAAGAAATGGCTTCTAGGACTGAGCTTGGTCCTCGCTCTGCTATTTTTCATAACCAAA
TACCCGCTGGAAAACGAGGTGACGGTGGTGGACATCGGGCAGGGGGACAGTATCTTTTTGCGGGATATGCGGGGGCGGAC
GGTTCTGATTGATGTGGGTGGTCGGGTTGATTTTGCGGCTAAGGAGGAGTGGCAGGAGCGGTCTTCGCAGGCAAATGCAG
AGCGGACTTTGATTCCCTATCTGCACAGTCGGGGCGTGGATAGGATTGATAGTCTAGTGCTGACCCACACCGACACAGAC
CATGTGGGCGATGTGCTAGAAGTGGCTAAGCAGGTACAAATTGGTCGAATTTACGTGTCGCCGGGAAGTCTGACGGTGCC
TGACTTTGTAGCGACTTTGAAAGAAATCAATGTCCCTGTTCATGTGGTGGCGGTAGGCGACCGCTTGCCGATTTTTGACT
CTTACCTAGAAGTCCTCTATCCAAGTGGAACGGGCGACGGTGGCAATAATGACTCTGTTGTTCTTTACGGTCGCTTGTTG
GAAACCAATTTTCTCTTTACAGGGGACTTGGAGCAAGGGGAGCTGGACTTGATCAAAACCTATCCCAATCTGCCTGTCGA
TGTCCTCAAAGCCGGTCACCACGGCTCTAAAGGTTCTTCCTATCCTGAATTTCTGGACCATATCGGAGCCAAGATTGCCT
TGGTATCTGCTGGAGAAAATAACCGCTACAAGCATCCCCATCAAGAAACCTTGGAACGCTTTGACAATCGGAATATCCAA
GTCTATCGAACTGATCAGCAGGGCGCCATTCGCTTTCGAGGTTGGAGGGAGTGGAGGATTGAAACGGTGAGGGAGTGA

Domains

Predicted by InterproScan.

Domain of unknown function (DUF4131) (DUF4131)

(30-176)

Competence protein (Competence)

(215-461)

Metallo-beta-lactamase superfamily (Lactamase_B)

(493-698)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC/celB Streptococcus mitis SK321

54.865

99.329

0.545
  comEC/celB Streptococcus mitis NCTC 12261

53.388

99.06

0.529
  comEC/celB Streptococcus pneumoniae TIGR4

53.125

98.792

0.525
  comEC/celB Streptococcus pneumoniae Rx1

52.582

98.792

0.519
  comEC/celB Streptococcus pneumoniae D39

52.582

98.792

0.519
  comEC/celB Streptococcus pneumoniae R6

52.582

98.792

0.519
  comEC Lactococcus lactis subsp. cremoris KW2

48.862

100

0.49