Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   U0N78_RS03070 Genome accession   NZ_CP140109
Coordinates   611863..612507 (-) Length   214 a.a.
NCBI ID   WP_029185181.1    Uniprot ID   A0A7T1P760
Organism   Streptococcus suis strain 2022WUSS148     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 606863..617507
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U0N78_RS03050 (U0N78_03050) - 607181..607702 (+) 522 WP_044767267.1 VanZ family protein -
  U0N78_RS03055 (U0N78_03055) trpB 608241..609416 (+) 1176 WP_044676961.1 tryptophan synthase subunit beta -
  U0N78_RS03060 (U0N78_03060) nadE 609458..610282 (-) 825 WP_044773306.1 ammonia-dependent NAD(+) synthetase -
  U0N78_RS03065 (U0N78_03065) - 610295..611755 (-) 1461 WP_029185182.1 nicotinate phosphoribosyltransferase -
  U0N78_RS03070 (U0N78_03070) cclA/cilC 611863..612507 (-) 645 WP_029185181.1 prepilin peptidase Machinery gene
  U0N78_RS03075 (U0N78_03075) - 612560..613378 (-) 819 WP_024378111.1 cation diffusion facilitator family transporter -
  U0N78_RS03080 (U0N78_03080) - 613500..614018 (+) 519 WP_024378110.1 TetR/AcrR family transcriptional regulator -
  U0N78_RS03085 (U0N78_03085) - 614028..614582 (+) 555 WP_029185180.1 class I SAM-dependent methyltransferase -
  U0N78_RS03090 (U0N78_03090) - 614598..615377 (-) 780 WP_105147129.1 ABC transporter ATP-binding protein -
  U0N78_RS03095 (U0N78_03095) - 615510..616847 (+) 1338 WP_002942867.1 hemolysin family protein -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24197.36 Da        Isoelectric Point: 8.4760

>NTDB_id=912573 U0N78_RS03070 WP_029185181.1 611863..612507(-) (cclA/cilC) [Streptococcus suis strain 2022WUSS148]
MKTIILFFLGASIGSFLGLVIDRFPEQSIIAPASHCNACKRRLKAWDLIPVLSQLSTKSKCRYCKAKIPYWYLGLEFLAG
LVVLLCHFQVLNLTETILILAGLVLTIYDIKHQEYPFAVWLIFTFIALVLSQLNWLFCGFLLLAYLTEKWQINIGSGDFL
YLASLALICGFTELLWIIQISSLLGLLVFAIFKPKSIPYVPLLFLSSIPIILCI

Nucleotide


Download         Length: 645 bp        

>NTDB_id=912573 U0N78_RS03070 WP_029185181.1 611863..612507(-) (cclA/cilC) [Streptococcus suis strain 2022WUSS148]
ATGAAGACAATTATCCTATTTTTCCTTGGAGCTTCTATCGGCTCCTTCCTGGGATTGGTCATCGACCGTTTCCCTGAACA
GTCCATTATCGCCCCAGCTAGTCACTGCAATGCTTGCAAACGACGGCTCAAGGCCTGGGACTTAATTCCAGTCCTATCCC
AGCTTTCGACAAAATCCAAATGCCGTTACTGCAAGGCGAAGATACCTTATTGGTATCTGGGACTAGAATTCTTAGCTGGT
CTAGTTGTCCTGCTCTGCCATTTTCAAGTCCTAAACCTAACCGAAACCATTCTCATCTTGGCAGGACTAGTTTTGACCAT
TTACGACATCAAACATCAGGAATATCCTTTTGCTGTCTGGCTCATTTTTACTTTTATAGCTCTGGTGCTCTCCCAGCTCA
ACTGGCTTTTCTGTGGCTTTTTACTCTTGGCCTATCTGACTGAAAAATGGCAAATCAATATTGGTTCTGGTGACTTTCTC
TATCTGGCAAGTTTGGCCTTAATATGTGGATTTACAGAACTCCTCTGGATTATCCAGATTAGTTCCCTCCTAGGGCTTCT
TGTCTTCGCCATTTTCAAACCCAAGTCTATTCCCTACGTACCACTCCTTTTTCTTTCAAGTATTCCTATCATTCTGTGCA
TCTAA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(9-88)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7T1P760

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus mitis SK321

50

99.065

0.495
  cclA/cilC Streptococcus pneumoniae Rx1

49.515

96.262

0.477
  cclA/cilC Streptococcus pneumoniae D39

49.515

96.262

0.477
  cclA/cilC Streptococcus pneumoniae R6

49.515

96.262

0.477
  cclA/cilC Streptococcus pneumoniae TIGR4

47.642

99.065

0.472
  cclA/cilC Streptococcus mitis NCTC 12261

46.226

99.065

0.458