Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   L6419_RS07555 Genome accession   NZ_AP025332
Coordinates   1588769..1590118 (-) Length   449 a.a.
NCBI ID   WP_024532081.1    Uniprot ID   A0A2Z5TLH3
Organism   Streptococcus ruminantium strain GUT-184     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1583769..1595118
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L6419_RS07540 (GUT184_14520) recR 1585056..1585652 (-) 597 WP_024532078.1 recombination mediator RecR -
  L6419_RS07545 (GUT184_14530) pbp2b 1585661..1587736 (-) 2076 WP_024532079.1 penicillin-binding protein PBP2B -
  L6419_RS07550 (GUT184_14540) vicX 1587959..1588762 (-) 804 WP_024532080.1 MBL fold metallo-hydrolase Regulator
  L6419_RS07555 (GUT184_14550) micB 1588769..1590118 (-) 1350 WP_024532081.1 cell wall metabolism sensor histidine kinase VicK Regulator
  L6419_RS07560 (GUT184_14560) micA 1590111..1590815 (-) 705 WP_120171458.1 response regulator YycF Regulator
  L6419_RS07565 (GUT184_14570) - 1591010..1591771 (+) 762 WP_237375267.1 amino acid ABC transporter ATP-binding protein -
  L6419_RS07570 (GUT184_14580) - 1591781..1592617 (+) 837 WP_237375268.1 transporter substrate-binding domain-containing protein -
  L6419_RS07575 (GUT184_14590) - 1592632..1593330 (+) 699 WP_155961912.1 amino acid ABC transporter permease -
  L6419_RS07580 (GUT184_14600) - 1593343..1594002 (+) 660 WP_120171455.1 amino acid ABC transporter permease -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 51069.15 Da        Isoelectric Point: 4.6687

>NTDB_id=91197 L6419_RS07555 WP_024532081.1 1588769..1590118(-) (micB) [Streptococcus ruminantium strain GUT-184]
MFNQLRYLITTAEFWFVGILIGFLIALTVLLIENYRDNKQIKQLNQKVNALIDGNYADILDLRGSPEITDMANSLNDLSE
VIRLTHDHLEQEKTRLTSILSYMSDGVVATDRIGRVIMINDMAQKQLGLSGKKQEQYHLLEVLDLPDRYTLRDLFAQTPE
IIIEHTNENEEFLTLRANFATIRSESGLISGLVVVLHDMTEQAKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALT
ESVAPSFVKVSLDETNRMIRMITDLLSLSRIDNQVGQVDVELINFTAFVTFILNRFDQMKNADSDKVYTIVRDYQISPIW
VEIDTDKMTQVLDNILNNAIKYSPDGGRITFSMKTTDSQLIVSISDEGLGIPKTDLPKIFDRFYRVDKARSRAQGGTGLG
LAIAKEIIKQHRGFIWAKSEYGHGSTFTIVLPYSKDIALDDWDEASEEE

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=91197 L6419_RS07555 WP_024532081.1 1588769..1590118(-) (micB) [Streptococcus ruminantium strain GUT-184]
ATGTTTAATCAATTACGGTATCTAATTACTACAGCAGAGTTTTGGTTTGTCGGAATTTTGATTGGTTTTCTGATTGCTTT
GACGGTTCTCTTGATTGAAAACTACCGAGATAATAAGCAAATCAAACAACTGAATCAAAAAGTTAATGCTCTCATTGATG
GAAATTATGCAGATATTTTAGATTTGAGAGGGAGTCCAGAAATTACTGATATGGCTAACTCTCTTAATGATTTGTCAGAA
GTTATTCGGCTGACTCATGATCATTTAGAGCAGGAAAAAACACGCTTGACTTCCATTCTTTCCTATATGAGTGATGGGGT
GGTTGCAACGGACAGGATTGGGCGAGTTATCATGATCAACGATATGGCCCAGAAGCAGTTGGGGTTATCGGGAAAAAAGC
AGGAACAGTACCATCTGCTAGAGGTGTTAGATTTACCAGATCGGTATACTCTCAGAGATTTGTTTGCTCAGACACCAGAG
ATTATTATTGAGCACACCAATGAAAATGAGGAATTTCTCACTCTTCGTGCCAATTTTGCTACCATTCGTAGCGAGAGCGG
CTTGATTTCAGGTCTAGTAGTCGTCTTGCACGATATGACCGAACAGGCCAAAGAAGAGCGAGAGCGGCGCTTATTCGTAT
CCAATGTCAGTCATGAATTGCGGACTCCTTTGACTTCTGTTAAGTCCTACTTAGAAGCCTTGGATGAAGGAGCTTTGACT
GAGTCGGTTGCCCCGAGTTTTGTCAAAGTATCCTTGGATGAAACCAATCGAATGATACGGATGATTACAGACTTGTTAAG
TCTCTCCCGAATCGACAATCAAGTTGGTCAGGTAGATGTGGAGCTGATCAATTTTACGGCTTTTGTAACCTTTATCCTCA
ACCGTTTTGACCAGATGAAAAATGCCGACTCTGATAAGGTTTACACCATTGTACGTGATTATCAGATTAGCCCAATTTGG
GTGGAGATTGATACTGATAAGATGACACAAGTTTTAGATAATATCCTGAACAATGCTATCAAATACTCACCTGATGGTGG
TAGGATTACTTTTAGTATGAAAACAACAGACAGCCAGTTGATTGTGTCTATTTCCGATGAAGGCTTGGGGATTCCAAAGA
CAGACTTACCTAAGATTTTCGACCGTTTTTATCGGGTAGACAAGGCACGCTCAAGGGCACAAGGAGGCACTGGCTTAGGA
CTGGCCATTGCCAAAGAAATCATCAAGCAACACAGGGGCTTTATTTGGGCTAAGAGCGAGTATGGCCATGGTTCAACCTT
TACCATTGTCTTACCATATAGTAAGGACATTGCTCTTGACGATTGGGATGAAGCTTCTGAGGAAGAATAG

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

PAS fold (PAS)

(96-199)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2Z5TLH3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

69.037

97.105

0.67
  vicK Streptococcus mutans UA159

69.479

89.755

0.624

Multiple sequence alignment