Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   ABVR74_RS10500 Genome accession   NZ_CP159484
Coordinates   2121078..2122520 (+) Length   480 a.a.
NCBI ID   WP_012897229.1    Uniprot ID   -
Organism   Lactococcus lactis subsp. lactis strain CBA3648     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 2116078..2127520
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABVR74_RS10465 (ABVR74_10465) - 2116282..2116473 (+) 192 WP_012897234.1 hypothetical protein -
  ABVR74_RS10470 (ABVR74_10470) rsmI 2116550..2117425 (-) 876 WP_058204088.1 16S rRNA (cytidine(1402)-2'-O)-methyltransferase -
  ABVR74_RS10475 (ABVR74_10475) yabA 2117425..2117751 (-) 327 WP_011675472.1 DNA replication initiation control protein YabA -
  ABVR74_RS10480 (ABVR74_10480) yaaT 2117744..2118526 (-) 783 WP_023188991.1 stage 0 sporulation family protein Regulator
  ABVR74_RS10485 (ABVR74_10485) - 2118578..2119438 (-) 861 WP_003131573.1 DNA polymerase III subunit delta' -
  ABVR74_RS10490 (ABVR74_10490) tmk 2119571..2120206 (-) 636 WP_012897230.1 dTMP kinase -
  ABVR74_RS10495 (ABVR74_10495) yycF 2120384..2121085 (+) 702 WP_003131580.1 response regulator YycF -
  ABVR74_RS10500 (ABVR74_10500) vicK 2121078..2122520 (+) 1443 WP_012897229.1 cell wall metabolism sensor histidine kinase WalK Regulator
  ABVR74_RS10505 (ABVR74_10505) vicX 2122689..2123501 (+) 813 WP_003131583.1 MBL fold metallo-hydrolase Regulator
  ABVR74_RS10510 (ABVR74_10510) groL 2123546..2125174 (-) 1629 WP_003131585.1 chaperonin GroEL -
  ABVR74_RS10515 (ABVR74_10515) groES 2125263..2125547 (-) 285 WP_003131589.1 co-chaperone GroES -
  ABVR74_RS10520 (ABVR74_10520) - 2125667..2126056 (-) 390 WP_010905314.1 single-stranded DNA-binding protein -
  ABVR74_RS10525 (ABVR74_10525) - 2126145..2127485 (-) 1341 WP_023188995.1 FAD-dependent oxidoreductase -

Sequence

Protein


Download         Length: 480 a.a.        Molecular weight: 54649.12 Da        Isoelectric Point: 4.5889

>NTDB_id=911684 ABVR74_RS10500 WP_012897229.1 2121078..2122520(+) (vicK) [Lactococcus lactis subsp. lactis strain CBA3648]
MIKFFNSMIFKGVVAHLLLFVILFMSSFDYNFAHLSTFIGYYLFSLVFVLVFLNQQHRMIVNVSKQMNDIKNGYLNRDKI
PKGTSEINELYDEILKLGEDIVRTQNNLENQRNQLDSILAYMVDGVIATDRRGNIIMANKSALHYLNTDNDLLMQKNIVE
VLKIADQYNFYDLLEKEPEITIETHDAGNESISLHIKFALFRRESGFISGIIAVLHDMTEQDKAERERRLFVSNVSHELR
TPLTSVKAYLEALEDGAIEDKETASSFINVSLTETNRMIRMISDLLTLSRMDQDRIVLNKEMINLIAFLDYQINRLDQIL
ETESNDLISSNFTLVRKYSEQPIWVEIDTDKIAQVIDNIIGNAIKYSPKGGTITISVEKRESDVLISISDQGMGIPKSDL
LKIFDRFYRVDNASRNSKVGGTGLGLSIVHDIVKIHGGTIFASSEGEGKGTTFSFTLPYSLEAADDWDDGTDEFEFEDNE

Nucleotide


Download         Length: 1443 bp        

>NTDB_id=911684 ABVR74_RS10500 WP_012897229.1 2121078..2122520(+) (vicK) [Lactococcus lactis subsp. lactis strain CBA3648]
ATGATTAAATTTTTTAATTCAATGATTTTTAAAGGAGTAGTTGCACACCTACTTCTTTTTGTCATCCTTTTTATGAGCAG
TTTTGATTACAATTTTGCTCATTTAAGTACTTTTATTGGTTATTACTTATTTTCACTCGTCTTTGTTTTAGTCTTTCTCA
ATCAGCAACATCGCATGATTGTGAATGTTTCTAAACAGATGAATGACATAAAAAATGGCTATTTAAATCGCGATAAAATC
CCAAAAGGGACGAGTGAAATCAATGAATTATATGATGAAATTTTAAAACTTGGTGAAGATATTGTTCGCACGCAGAACAA
TCTTGAAAATCAGCGCAATCAATTAGATAGTATTCTCGCATATATGGTTGATGGCGTCATTGCCACCGATCGTCGTGGAA
ATATTATTATGGCCAATAAATCAGCTTTGCATTATTTGAATACAGATAATGATCTCTTGATGCAAAAAAATATTGTTGAA
GTTTTAAAAATTGCTGACCAATATAATTTTTATGATTTATTAGAAAAAGAACCTGAAATAACTATTGAGACACATGATGC
TGGGAATGAATCCATTTCGCTCCACATTAAATTTGCCCTCTTTCGTCGTGAATCTGGTTTCATCTCAGGAATTATTGCCG
TCTTACATGATATGACTGAACAAGACAAGGCCGAACGAGAGCGCCGTCTCTTTGTTTCCAATGTTTCTCATGAACTCCGA
ACTCCGCTCACCTCAGTAAAAGCCTACTTGGAAGCACTAGAAGACGGAGCCATTGAGGATAAAGAAACAGCTTCATCCTT
TATTAATGTTTCACTTACTGAAACTAATCGGATGATTCGAATGATTTCCGACCTTTTGACTTTATCAAGAATGGATCAAG
ACCGAATCGTTCTTAATAAAGAAATGATTAATTTAATTGCCTTCTTAGACTATCAAATTAACCGTTTAGACCAAATTTTA
GAAACCGAATCAAACGATTTAATCTCTTCTAATTTCACACTAGTCAGAAAATACTCTGAACAGCCCATCTGGGTCGAAAT
TGATACCGATAAAATTGCTCAAGTCATTGACAATATCATCGGAAATGCAATTAAGTATTCACCTAAAGGTGGAACTATTA
CAATTTCCGTTGAAAAACGTGAAAGTGATGTTCTAATCTCCATCAGTGACCAAGGAATGGGAATTCCAAAATCTGATTTA
CTTAAGATTTTTGACCGTTTCTACCGAGTTGATAATGCTTCAAGAAATTCAAAAGTTGGGGGGACAGGTTTAGGCCTCTC
CATTGTCCATGATATTGTTAAAATACATGGCGGAACAATTTTTGCAAGCTCCGAAGGAGAAGGAAAAGGAACGACCTTTA
GTTTCACTCTTCCATATTCTTTAGAAGCCGCAGATGACTGGGATGATGGCACTGATGAGTTTGAATTTGAGGATAATGAA
TAA

Domains

Predicted by InterProScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(348-459)

PAS domain (PAS_9)

(124-220)

His Kinase A (phospho-acceptor) domain (HisKA)

(228-293)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

51.559

86.875

0.448
  micB Streptococcus pneumoniae Cp1015

47.748

92.5

0.442