Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   U0450_RS06320 Genome accession   NZ_CP139863
Coordinates   1261987..1262940 (+) Length   317 a.a.
NCBI ID   WP_050233486.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 15P2112     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1256987..1267940
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U0450_RS06275 - 1257044..1257409 (+) 366 WP_050212688.1 DUF1033 family protein -
  U0450_RS06280 comGA/cglA/cilD 1257485..1258426 (+) 942 WP_000249571.1 competence type IV pilus ATPase ComGA Machinery gene
  U0450_RS06285 comGB/cglB 1258374..1259390 (+) 1017 WP_078134945.1 competence type IV pilus assembly protein ComGB Machinery gene
  U0450_RS06290 comGC/cglC 1259392..1259718 (+) 327 WP_000738636.1 comG operon protein ComGC Machinery gene
  U0450_RS06295 comGD/cglD 1259711..1260115 (+) 405 WP_000588013.1 competence type IV pilus minor pilin ComGD Machinery gene
  U0450_RS06300 comGE/cglE 1260078..1260380 (+) 303 WP_226372546.1 competence type IV pilus minor pilin ComGE Machinery gene
  U0450_RS06305 comGF/cglF 1260343..1260804 (+) 462 WP_000250542.1 competence type IV pilus minor pilin ComGF Machinery gene
  U0450_RS06310 comGG/cglG 1260782..1261195 (+) 414 WP_000265624.1 competence type IV pilus minor pilin ComGG Machinery gene
  U0450_RS06315 - 1261332..1261926 (+) 595 Protein_1232 class I SAM-dependent methyltransferase -
  U0450_RS06320 comYH 1261987..1262940 (+) 954 WP_050233486.1 class I SAM-dependent methyltransferase Machinery gene
  U0450_RS06325 - 1262991..1264181 (+) 1191 WP_050233485.1 acetate kinase -
  U0450_RS06330 - 1264182..1264313 (+) 132 WP_000768904.1 hypothetical protein -
  U0450_RS06335 rnpA 1264330..1264701 (+) 372 WP_000739246.1 ribonuclease P protein component -
  U0450_RS06340 - 1264676..1265500 (+) 825 WP_201417385.1 membrane protein insertase YidC -
  U0450_RS06345 jag 1265519..1266505 (+) 987 WP_000260018.1 RNA-binding cell elongation regulator Jag/EloR -
  U0450_RS06350 - 1266556..1267179 (+) 624 WP_050233484.1 hypothetical protein -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 35646.83 Da        Isoelectric Point: 4.2585

>NTDB_id=911576 U0450_RS06320 WP_050233486.1 1261987..1262940(+) (comYH) [Streptococcus pneumoniae strain 15P2112]
MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGETELEQVKDNNQTLKRLALRKEEWLKTYQFLLMKAGQT
EPLQANHQFTPDAIALLLVFIVEELFTEEEITILEMGSGMGILGATFLTSLTKKVDYLGMEVDDLLIDLAASMADVIGLQ
AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGLKYLKSDGYAIFLAPSDLLTSPQ
SNLLKVWLKEEASLVAMISLPENLFANAKQSKTIFILQKKSEVAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI

Nucleotide


Download         Length: 954 bp        

>NTDB_id=911576 U0450_RS06320 WP_050233486.1 1261987..1262940(+) (comYH) [Streptococcus pneumoniae strain 15P2112]
ATGGATTTTGAAAAAATTGAACAAGCTTATACCTATTTACTAGAGAATGTCCAAGTCATCCAAAGTGATTTGGCGACCAA
CTTTTATGACGCCTTGGTGGAGCAAAACAGCATCTATCTGGATGGTGAGACTGAGCTAGAACAGGTCAAAGACAACAATC
AGACCCTTAAGCGTTTAGCACTACGCAAAGAAGAATGGCTCAAGACCTACCAGTTTCTCTTGATGAAGGCTGGGCAAACA
GAACCCTTGCAGGCCAATCACCAGTTTACGCCAGATGCTATTGCCTTACTTTTGGTATTTATTGTGGAAGAGTTGTTTAC
AGAGGAGGAAATTACTATCCTCGAAATGGGTTCTGGGATGGGAATTTTGGGCGCTACTTTCTTGACCTCGCTTACTAAAA
AGGTGGATTATTTGGGAATGGAAGTGGATGATTTGCTGATTGATTTGGCAGCTAGCATGGCAGATGTAATTGGTTTGCAG
GCTGGCTTTGTCCAAGGAGATGCCGTTCGTCCACAAATGCTCAAAGAAAGTGATGTGGTCATCAGCGACTTGCCTGTTGG
CTATTATCCTGATGATGCCGTTGCGTCGCGCCATCAAGTTGCTTCTAGTCAAGAACATACTTACGCCCATCACTTGCTCA
TGGAACAAGGACTTAAGTACCTCAAGTCAGACGGATACGCTATTTTTCTAGCTCCGAGTGATTTGTTGACCAGTCCTCAA
AGTAATTTGTTGAAAGTCTGGTTGAAAGAGGAGGCAAGTCTGGTTGCTATGATTAGTTTACCTGAAAATCTCTTTGCTAA
TGCTAAACAATCTAAGACTATTTTTATCCTACAGAAGAAAAGTGAAGTAGCAGTAGAGCCTTTTGTTTATCCACTTGCTA
GCTTGCAAGATGCAAGTGTTTTAATGAAATTTAAAGAAAATTTTCAAAAATGGACTCAAGGTACTGAAATATAA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(69-282)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA140

54.952

98.738

0.543
  comYH Streptococcus mutans UA159

54.633

98.738

0.539