Detailed information NTG0911571

Bioinformatically predicted

Overview

• Name: comGC/cglC
• Type: Machinery gene
• Locus tag: U0450_RS06290
• Genome accession: NZ_CP139863
• Coordinates: 1259392..1259718 (+)
• Length: 108 a.a.
• NCBI ID: WP_000738636.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 15P2112
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1254392..1264718

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
U0450_RS06265	nagA	1254521..1255672 (+)	1152	WP_001134457.1	N-acetylglucosamine-6-phosphate deacetylase	-
U0450_RS06270	-	1255835..1256893 (+)	1059	WP_000649468.1	zinc-dependent alcohol dehydrogenase family protein	-
U0450_RS06275	-	1257044..1257409 (+)	366	WP_050212688.1	DUF1033 family protein	-
U0450_RS06280	comGA/cglA/cilD	1257485..1258426 (+)	942	WP_000249571.1	competence type IV pilus ATPase ComGA	Machinery gene
U0450_RS06285	comGB/cglB	1258374..1259390 (+)	1017	WP_078134945.1	competence type IV pilus assembly protein ComGB	Machinery gene
U0450_RS06290	comGC/cglC	1259392..1259718 (+)	327	WP_000738636.1	comG operon protein ComGC	Machinery gene
U0450_RS06295	comGD/cglD	1259711..1260115 (+)	405	WP_000588013.1	competence type IV pilus minor pilin ComGD	Machinery gene
U0450_RS06300	comGE/cglE	1260078..1260380 (+)	303	WP_226372546.1	competence type IV pilus minor pilin ComGE	Machinery gene
U0450_RS06305	comGF/cglF	1260343..1260804 (+)	462	WP_000250542.1	competence type IV pilus minor pilin ComGF	Machinery gene
U0450_RS06310	comGG/cglG	1260782..1261195 (+)	414	WP_000265624.1	competence type IV pilus minor pilin ComGG	Machinery gene
U0450_RS06315	-	1261332..1261926 (+)	595	Protein_1232	class I SAM-dependent methyltransferase	-
U0450_RS06320	comYH	1261987..1262940 (+)	954	WP_050233486.1	class I SAM-dependent methyltransferase	Machinery gene
U0450_RS06325	-	1262991..1264181 (+)	1191	WP_050233485.1	acetate kinase	-
U0450_RS06330	-	1264182..1264313 (+)	132	WP_000768904.1	hypothetical protein	-
U0450_RS06335	rnpA	1264330..1264701 (+)	372	WP_000739246.1	ribonuclease P protein component	-

Sequence

Protein

• Length: 108 a.a.
• Molecular weight: 12208.39 Da
• Isoelectric Point: 10.0305

>NTDB_id=911571 U0450_RS06290 WP_000738636.1 1259392..1259718(+) (comGC/cglC) [Streptococcus pneumoniae strain 15P2112]
MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKEAVNDKGKAAVVKVVESQAELYSLEKNEDASLSKLKE
DGRITEEQAKAYKEYNDKNVGANRKVND

Nucleotide

• Length: 327 bp

>NTDB_id=911571 U0450_RS06290 WP_000738636.1 1259392..1259718(+) (comGC/cglC) [Streptococcus pneumoniae strain 15P2112]
ATGAAAAAAATGATGACATTCTTGAAAAAAGCTAAGGTTAAAGCTTTTACATTGGTGGAGATGTTGGTGGTCTTGCTGAT
TATCAGCGTGCTTTTCTTGCTCTTTGTACCTAATCTGACCAAGCAAAAAGAAGCAGTCAATGACAAAGGAAAAGCAGCTG
TTGTTAAGGTGGTGGAAAGCCAGGCAGAACTTTATAGCTTGGAAAAGAATGAAGATGCTAGCCTAAGCAAGTTAAAAGAA
GATGGACGCATCACGGAAGAACAGGCTAAAGCTTATAAAGAATACAATGATAAAAATGTGGGAGCAAATCGTAAAGTCAA
TGATTAA

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (11-34)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGC/cglC	Streptococcus pneumoniae TIGR4	96.296	100	0.963
comGC/cglC	Streptococcus pneumoniae Rx1	95.37	100	0.954
comGC/cglC	Streptococcus pneumoniae D39	95.37	100	0.954
comGC/cglC	Streptococcus pneumoniae R6	95.37	100	0.954
comGC/cglC	Streptococcus mitis SK321	92.593	100	0.926
comGC/cglC	Streptococcus mitis NCTC 12261	93.878	90.741	0.852
comYC	Streptococcus gordonii str. Challis substr. CH1	71.875	88.889	0.639
comYC	Streptococcus mutans UA159	62.745	94.444	0.593
comYC	Streptococcus mutans UA140	62.745	94.444	0.593
comGC	Lactococcus lactis subsp. cremoris KW2	54.902	94.444	0.519
comYC	Streptococcus suis isolate S10	67.901	75	0.509
comGC	Staphylococcus aureus MW2	48.837	79.63	0.389
comGC	Staphylococcus aureus N315	48.837	79.63	0.389
comGC	Latilactobacillus sakei subsp. sakei 23K	45.349	79.63	0.361