Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFC/cflB   Type   Machinery gene
Locus tag   U0450_RS05445 Genome accession   NZ_CP139863
Coordinates   1082684..1083346 (+) Length   220 a.a.
NCBI ID   WP_000649964.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 15P2112     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1077684..1088346
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U0450_RS05415 tnpB 1078121..1078444 (+) 324 WP_000586641.1 IS66 family insertion sequence element accessory protein TnpB -
  U0450_RS05420 - 1078599..1078907 (-) 309 Protein_1068 transposase -
  U0450_RS05425 - 1078880..1079418 (+) 539 Protein_1069 transposase -
  U0450_RS05430 cysK 1079493..1080413 (-) 921 WP_000029866.1 cysteine synthase A -
  U0450_RS05435 - 1080698..1081333 (-) 636 WP_000395730.1 YigZ family protein -
  U0450_RS05440 comFA/cflA 1081389..1082687 (+) 1299 WP_050233596.1 DEAD/DEAH box helicase Machinery gene
  U0450_RS05445 comFC/cflB 1082684..1083346 (+) 663 WP_000649964.1 ComF family protein Machinery gene
  U0450_RS05450 hpf 1083426..1083974 (+) 549 WP_000599107.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  U0450_RS05455 - 1084110..1086083 (+) 1974 WP_050205401.1 DHH family phosphoesterase -
  U0450_RS05460 rplI 1086080..1086532 (+) 453 WP_050114792.1 50S ribosomal protein L9 -
  U0450_RS05465 dnaB 1086576..1087928 (+) 1353 WP_050114789.1 replicative DNA helicase -
  U0450_RS05470 - 1087930..1088196 (+) 267 WP_001278167.1 Veg family protein -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 25253.15 Da        Isoelectric Point: 7.3688

>NTDB_id=911562 U0450_RS05445 WP_000649964.1 1082684..1083346(+) (comFC/cflB) [Streptococcus pneumoniae strain 15P2112]
MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEENCPNCMKTELSIKCQDCQLWCKEGVEVSHRAIFTYNQ
AMKDFFSRYKFDGDFLLRKVFASFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSLVR

Nucleotide


Download         Length: 663 bp        

>NTDB_id=911562 U0450_RS05445 WP_000649964.1 1082684..1083346(+) (comFC/cflB) [Streptococcus pneumoniae strain 15P2112]
ATGAAGTGCTTGTTATGTGGGCAGACTATGAAGACTGTTTTAACTTTTAGTAGTCTCTTACTTCTGAGGAATGATGACTC
TTGTCTTTGTTCAGACTGTGATTCTACTTTTGAAAGAATTGGGGAAGAGAACTGTCCAAATTGTATGAAAACAGAGTTGT
CAATAAAGTGTCAAGATTGTCAACTTTGGTGTAAAGAGGGAGTTGAAGTCAGTCATAGAGCGATTTTTACTTACAATCAA
GCTATGAAGGATTTTTTCAGTCGGTATAAGTTTGATGGAGACTTCCTGTTAAGAAAAGTTTTCGCTTCATTTTTAAGTGA
GGAGTTGAAAAAGTACAAAGAGTATCAATTTGTTGTAATTCCCCTAAGTCCTGATAGATATGCTAATAGAGGATTTAATC
AGGTTGAGGGCTTGGTAGAGGCAGCAGGCTTTGAGTATCTGGATTTATTAGAGAAAAGAGAAGAGAGAGCCAGTTCTTCT
AAAAATCGTTCAGAGCGCTTGGGGACAGAACTTCCTTTCTTTATTAAAAGTGGAGTCACTATTCCTAAAAAAATCCTACT
TATAGATGATATCTATACTACAGGAGCAACTATAAATCGTGTTAAGAAACTGTTGGAAGAAGCTGGTGCTAAGGATGTAA
AAACATTTTCCCTTGTAAGATGA

Domains

Predicted by InterproScan.

Phosphoribosyl transferase domain (Pribosyltran)

(153-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFC/cflB Streptococcus pneumoniae TIGR4

99.545

100

0.995
  comFC/cflB Streptococcus pneumoniae Rx1

99.091

100

0.991
  comFC/cflB Streptococcus pneumoniae D39

99.091

100

0.991
  comFC/cflB Streptococcus pneumoniae R6

99.091

100

0.991
  comFC/cflB Streptococcus mitis NCTC 12261

91.818

100

0.918
  comFC/cflB Streptococcus mitis SK321

90.909

100

0.909