Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   U0449_RS07505 Genome accession   NZ_CP139862
Coordinates   1460003..1460662 (-) Length   219 a.a.
NCBI ID   WP_050168228.1    Uniprot ID   A0A4J2EJU5
Organism   Streptococcus pneumoniae strain 05H0020-2     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1455003..1465662
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U0449_RS07475 - 1455183..1455782 (+) 600 WP_000169888.1 phosphoribosylanthranilate isomerase -
  U0449_RS07480 trpB 1455760..1456983 (+) 1224 WP_000331298.1 tryptophan synthase subunit beta -
  U0449_RS07485 trpA 1456976..1457752 (+) 777 WP_001126993.1 tryptophan synthase subunit alpha -
  U0449_RS07490 - 1457724..1457873 (-) 150 Protein_1432 prepilin peptidase -
  U0449_RS07495 - 1458054..1458785 (+) 732 WP_000934017.1 hypothetical protein -
  U0449_RS07500 - 1458800..1459951 (+) 1152 WP_050218970.1 XRE family transcriptional regulator -
  U0449_RS07505 cclA/cilC 1460003..1460662 (-) 660 WP_050168228.1 A24 family peptidase Machinery gene
  U0449_RS07510 - 1460732..1461130 (+) 399 WP_050102521.1 GNAT family N-acetyltransferase -
  U0449_RS07515 - 1461406..1462584 (-) 1179 WP_000175876.1 ROK family transcriptional regulator -
  U0449_RS07520 - 1462864..1464126 (+) 1263 WP_050218971.1 PTS sugar transporter subunit IIC -
  U0449_RS07525 - 1464129..1465025 (+) 897 WP_000825669.1 PEP phosphonomutase -
  U0449_RS07530 - 1465040..1465357 (+) 318 WP_001151646.1 PTS sugar transporter subunit IIB -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24860.02 Da        Isoelectric Point: 7.5762

>NTDB_id=911517 U0449_RS07505 WP_050168228.1 1460003..1460662(-) (cclA/cilC) [Streptococcus pneumoniae strain 05H0020-2]
MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLRPLDLIPILSQVFNRFCCRYCKVRYPVWYALFELGLG
LLFLLYSWELLSLSQVILITAGLTLGIYDFRHQEYPLLVWMTFHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLAACLIIFGKLLLV

Nucleotide


Download         Length: 660 bp        

>NTDB_id=911517 U0449_RS07505 WP_050168228.1 1460003..1460662(-) (cclA/cilC) [Streptococcus pneumoniae strain 05H0020-2]
ATGATTGATTTTTATTTTTTTCTCGTCGGGAGCATTCTCGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGCA
ATCCATTATCAGTTCAGCCAGTCACTGCGATTCCTGTCAGACTCGCTTGCGTCCCTTAGATTTGATTCCGATTCTCTCAC
AGGTCTTCAATCGCTTTTGCTGTCGCTACTGCAAGGTCCGCTATCCTGTCTGGTATGCCCTCTTTGAACTAGGCTTAGGA
CTCCTCTTTCTGCTTTACTCTTGGGAATTACTTTCCTTGAGTCAAGTCATCCTAATCACTGCTGGTTTGACCTTGGGCAT
CTACGACTTTCGCCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCACCTAATCCTAATAGCTTCCTCTGGCTGGA
ATCTGGTCATGGTCTCCTTCCTCATACTTGGAATTTTGGCTCATTTTATCGATATCCGCATGGGTGCAGGGGATTTCCTT
TTTTTAGCTTCTTGCGCTCTCGTCTTTAGCGTAACGGAGTTACTGATCTTGATTCAGTTCGCTTCTGCGACGGGTATCCT
GGCCTTTCTCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTGCTTGTTTGATTATTTTTG
GTAAGCTACTGCTTGTCTGA

Domains

Predicted by InterProScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-89)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus pneumoniae Rx1

99.543

100

0.995
  cclA/cilC Streptococcus pneumoniae D39

99.543

100

0.995
  cclA/cilC Streptococcus pneumoniae R6

99.543

100

0.995
  cclA/cilC Streptococcus pneumoniae TIGR4

95.434

100

0.954
  cclA/cilC Streptococcus mitis SK321

92.237

100

0.922
  cclA/cilC Streptococcus mitis NCTC 12261

87.215

100

0.872