Detailed information    

insolico Bioinformatically predicted

Overview

Name   comW   Type   Regulator
Locus tag   U0449_RS05070 Genome accession   NZ_CP139862
Coordinates   1003918..1004154 (-) Length   78 a.a.
NCBI ID   WP_000939548.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 05H0020-2     
Function   stabilization and activation of ComX (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IScluster/Tn 1004471..1005575 1003918..1004154 flank 317


Gene organization within MGE regions


Location: 1003918..1005575
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U0449_RS05070 comW 1003918..1004154 (-) 237 WP_000939548.1 sigma(X)-activator ComW Regulator
  U0449_RS05075 - 1004420..1005217 (+) 798 Protein_1010 transposase -

Sequence

Protein


Download         Length: 78 a.a.        Molecular weight: 9716.17 Da        Isoelectric Point: 6.7051

>NTDB_id=911477 U0449_RS05070 WP_000939548.1 1003918..1004154(-) (comW) [Streptococcus pneumoniae strain 05H0020-2]
MLQKIYEQMTNFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVRYGIGCRRDFIVYHYRVAYRLYLEKLVMNRGFISC

Nucleotide


Download         Length: 237 bp        

>NTDB_id=911477 U0449_RS05070 WP_000939548.1 1003918..1004154(-) (comW) [Streptococcus pneumoniae strain 05H0020-2]
ATGTTACAAAAAATTTATGAGCAGATGACTAATTTCTATGATAGTATTGAAGAAGAGTATGGTCCTACATTTGGTGATAA
TTTTGACTGGGAACATGTTCATTTTAAATTTTTAATTTATTATTTAGTGAGATATGGCATTGGTTGTCGTAGGGATTTTA
TCGTTTACCATTATCGTGTTGCTTATCGTTTGTATCTTGAAAAATTGGTAATGAATCGGGGTTTTATTTCTTGTTGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comW Streptococcus pneumoniae Rx1

97.436

100

0.974
  comW Streptococcus pneumoniae D39

97.436

100

0.974
  comW Streptococcus pneumoniae R6

97.436

100

0.974
  comW Streptococcus pneumoniae TIGR4

97.436

100

0.974
  comW Streptococcus mitis SK321

76.923

100

0.769
  comW Streptococcus mitis NCTC 12261

76.623

98.718

0.756