Detailed information    

insolico Bioinformatically predicted

Overview


Name   comW   Type   Regulator
Locus tag   U0447_RS05595 Genome accession   NZ_CP139861
Coordinates   1063475..1063711 (+) Length   78 a.a.
NCBI ID   WP_000939546.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 16H2017-2     
Function   stabilization and activation of ComX (predicted from homology)   
Competence regulation

Genomic Context


Location: 1058475..1068711
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U0447_RS05585 - 1061528..1062378 (+) 851 Protein_1046 IS630 family transposase -
  U0447_RS05590 - 1062413..1063210 (-) 798 Protein_1047 transposase -
  U0447_RS05595 comW 1063475..1063711 (+) 237 WP_000939546.1 sigma(X)-activator ComW Regulator
  U0447_RS05600 - 1063942..1065228 (+) 1287 WP_001819018.1 adenylosuccinate synthase -
  U0447_RS05605 tadA 1065429..1065896 (+) 468 WP_000291875.1 tRNA adenosine(34) deaminase TadA -
  U0447_RS05615 - 1066083..1066526 (+) 444 WP_000701974.1 dUTP diphosphatase -
  U0447_RS05620 - 1066528..1067043 (+) 516 WP_000691236.1 histidine phosphatase family protein -
  U0447_RS05625 radA 1067057..1068418 (+) 1362 WP_078143130.1 DNA repair protein RadA Machinery gene

Sequence


Protein


Download         Length: 78 a.a.        Molecular weight: 9686.14 Da        Isoelectric Point: 6.7051

>NTDB_id=911431 U0447_RS05595 WP_000939546.1 1063475..1063711(+) (comW) [Streptococcus pneumoniae strain 16H2017-2]
MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVRYGIGCRRDFIVYHYRVAYRLYLEKLVMNRGFISC

Nucleotide


Download         Length: 237 bp        

>NTDB_id=911431 U0447_RS05595 WP_000939546.1 1063475..1063711(+) (comW) [Streptococcus pneumoniae strain 16H2017-2]
ATGTTACAAAAAATTTATGAGCAGATGGCTAATTTCTATGATAGTATTGAAGAAGAGTATGGTCCTACATTTGGTGATAA
TTTTGACTGGGAACATGTTCATTTTAAATTTTTAATTTATTATTTAGTGAGATATGGCATTGGTTGTCGTAGGGATTTTA
TCGTTTACCATTATCGTGTTGCTTATCGTTTGTATCTTGAAAAATTGGTAATGAATCGGGGTTTTATTTCTTGTTGA

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comW Streptococcus pneumoniae Rx1

98.718

100

0.987

  comW Streptococcus pneumoniae D39

98.718

100

0.987

  comW Streptococcus pneumoniae R6

98.718

100

0.987

  comW Streptococcus pneumoniae TIGR4

98.718

100

0.987

  comW Streptococcus mitis SK321

76.923

100

0.769

  comW Streptococcus mitis NCTC 12261

76.623

98.718

0.756