Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFC/cflB   Type   Machinery gene
Locus tag   U0447_RS05305 Genome accession   NZ_CP139861
Coordinates   1007960..1008622 (-) Length   220 a.a.
NCBI ID   WP_000649971.1    Uniprot ID   A0A0B7MFB3
Organism   Streptococcus pneumoniae strain 16H2017-2     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1002960..1013622
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U0447_RS05280 - 1003110..1003376 (-) 267 WP_001278167.1 Veg family protein -
  U0447_RS05285 dnaB 1003378..1004730 (-) 1353 WP_000852486.1 replicative DNA helicase -
  U0447_RS05290 rplI 1004774..1005226 (-) 453 WP_000864220.1 50S ribosomal protein L9 -
  U0447_RS05295 - 1005223..1007196 (-) 1974 WP_000715129.1 DHH family phosphoesterase -
  U0447_RS05300 hpf 1007332..1007880 (-) 549 WP_033705088.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  U0447_RS05305 comFC/cflB 1007960..1008622 (-) 663 WP_000649971.1 ComF family protein Machinery gene
  U0447_RS05310 comFA/cflA 1008619..1009917 (-) 1299 WP_000867590.1 DEAD/DEAH box helicase Machinery gene
  U0447_RS05315 - 1009973..1010608 (+) 636 WP_000395739.1 YigZ family protein -
  U0447_RS05320 cysK 1010893..1011813 (+) 921 WP_000029860.1 cysteine synthase A -
  U0447_RS05325 - 1011888..1012426 (-) 539 Protein_1003 transposase -
  U0447_RS05330 - 1012399..1012686 (+) 288 Protein_1004 transposase -
  U0447_RS05335 tnpB 1012928..1013095 (-) 168 WP_224781431.1 IS66 family insertion sequence element accessory protein TnpB -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 25241.10 Da        Isoelectric Point: 7.3688

>NTDB_id=911423 U0447_RS05305 WP_000649971.1 1007960..1008622(-) (comFC/cflB) [Streptococcus pneumoniae strain 16H2017-2]
MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEENCPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQ
AMKDFFSRYKFDGDFLLRKVFASFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSLVR

Nucleotide


Download         Length: 663 bp        

>NTDB_id=911423 U0447_RS05305 WP_000649971.1 1007960..1008622(-) (comFC/cflB) [Streptococcus pneumoniae strain 16H2017-2]
ATGAAGTGCTTGTTATGTGGGCAGACTATGAAGACTGTTTTAACTTTTAGTAGTCTCTTACTTCTGAGGAATGATGACTC
TTGTCTTTGTTCAGACTGTGATTCTACTTTTGAAAGAATTGGGGAAGAGAACTGTCCAAATTGTATGAAAACAGAGTTGT
CAACAAAGTGTCAAGATTGTCAACTTTGGTGTAAAGAGGGAGTTGAAGTCAGTCATAGAGCGATTTTTACTTACAATCAA
GCTATGAAGGATTTTTTCAGTCGGTATAAGTTTGATGGAGACTTCCTGTTAAGAAAAGTTTTCGCTTCATTTTTAAGTGA
GGAGTTGAAAAAGTACAAAGAGTATCAATTTGTTGTAATTCCCCTAAGTCCTGATAGATATGCTAATAGAGGATTTAATC
AGGTTGAGGGCTTGGTAGAGGCAGCAGGCTTTGAGTATCTGGATTTATTAGAGAAAAGAGAAGAGAGAGCCAGTTCTTCT
AAAAATCGTTCAGAGCGCTTGGGGACAGAACTTCCTTTCTTTATTAAAAGTGGAGTCACTATTCCTAAAAAAATCCTACT
TATAGATGATATCTATACTACAGGAGCAACTATAAATCGTGTTAAGAAACTGTTGGAAGAAGCTGGTGCTAAGGATGTAA
AAACATTTTCCCTTGTAAGATGA

Domains

Predicted by InterproScan.

Phosphoribosyl transferase domain (Pribosyltran)

(153-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7MFB3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFC/cflB Streptococcus pneumoniae TIGR4

100

100

1
  comFC/cflB Streptococcus pneumoniae Rx1

99.545

100

0.995
  comFC/cflB Streptococcus pneumoniae D39

99.545

100

0.995
  comFC/cflB Streptococcus pneumoniae R6

99.545

100

0.995
  comFC/cflB Streptococcus mitis NCTC 12261

91.818

100

0.918
  comFC/cflB Streptococcus mitis SK321

91.364

100

0.914