Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   U0448_RS03015 Genome accession   NZ_CP139860
Coordinates   618317..618976 (+) Length   219 a.a.
NCBI ID   WP_000565005.1    Uniprot ID   A0A0B7LMM1
Organism   Streptococcus pneumoniae strain 21011     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 613317..623976
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U0448_RS02995 - 613954..614850 (-) 897 WP_061751773.1 hypothetical protein -
  U0448_RS03000 - 614853..616115 (-) 1263 WP_000413335.1 PTS sugar transporter subunit IIC -
  U0448_RS03005 - 616395..617573 (+) 1179 WP_000175882.1 ROK family transcriptional regulator -
  U0448_RS03010 - 617801..618247 (-) 447 WP_000155433.1 GNAT family N-acetyltransferase -
  U0448_RS03015 cclA/cilC 618317..618976 (+) 660 WP_000565005.1 A24 family peptidase Machinery gene
  U0448_RS03020 - 619028..620179 (-) 1152 WP_000481754.1 XRE family transcriptional regulator -
  U0448_RS03025 - 620194..620925 (-) 732 WP_000934018.1 hypothetical protein -
  U0448_RS03030 - 621151..621255 (+) 105 Protein_601 prepilin peptidase -
  U0448_RS03035 trpA 621227..622003 (-) 777 WP_001126994.1 tryptophan synthase subunit alpha -
  U0448_RS03040 trpB 621996..623219 (-) 1224 WP_000331292.1 tryptophan synthase subunit beta -
  U0448_RS03045 - 623197..623796 (-) 600 WP_050198592.1 phosphoribosylanthranilate isomerase -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24846.03 Da        Isoelectric Point: 7.8950

>NTDB_id=911313 U0448_RS03015 WP_000565005.1 618317..618976(+) (cclA/cilC) [Streptococcus pneumoniae strain 21011]
MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLRPLDLIPILSQVFNRFCCRYCKVRYPVWYALFELGLG
LLFLLYSWELLSLSKVILITAGLTLGIYDFRHQEYPLLVWMTFHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLAACVIIFGKLLLV

Nucleotide


Download         Length: 660 bp        

>NTDB_id=911313 U0448_RS03015 WP_000565005.1 618317..618976(+) (cclA/cilC) [Streptococcus pneumoniae strain 21011]
ATGATTGATTTTTATTTTTTTCTCGTCGGGAGCATTCTAGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGCA
ATCCATTATCAGTTCAGCCAGTCACTGCGATTCCTGTCAGACTCGCTTGCGTCCCTTAGATTTGATTCCGATTCTCTCAC
AGGTCTTCAATCGCTTTTGCTGTCGCTACTGCAAGGTCCGCTATCCTGTCTGGTATGCCCTCTTTGAACTAGGCTTAGGA
CTCCTCTTTCTGCTTTACTCTTGGGAATTACTTTCCTTGAGTAAAGTCATCCTAATCACTGCTGGTTTGACCTTGGGCAT
CTACGACTTTCGCCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCACCTAATCCTAATAGCTTCCTCTGGCTGGA
ATCTGGTCATGGTCTCCTTCCTCATACTTGGAATTTTGGCTCATTTTATCGATATCCGCATGGGTGCAGGGGATTTCCTT
TTTTTAGCTTCTTGCGCTCTCGTCTTTAGCGTAACGGAGTTACTGATCTTGATTCAGTTCGCTTCTGCGACGGGTATCCT
GGCCTTTCTCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTGCTTGTGTGATTATTTTTG
GTAAGCTACTGCTTGTTTGA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-89)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7LMM1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus pneumoniae Rx1

99.543

100

0.995
  cclA/cilC Streptococcus pneumoniae D39

99.543

100

0.995
  cclA/cilC Streptococcus pneumoniae R6

99.543

100

0.995
  cclA/cilC Streptococcus pneumoniae TIGR4

94.521

100

0.945
  cclA/cilC Streptococcus mitis SK321

92.237

100

0.922
  cclA/cilC Streptococcus mitis NCTC 12261

87.215

100

0.872