Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   SO785_RS00005 Genome accession   NZ_CP139575
Coordinates   1978269..1584 (+) Length   721 a.a.
NCBI ID   WP_011254576.1    Uniprot ID   Q5FI74
Organism   Lactobacillus acidophilus strain ATCC 4356     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1973269..6584
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  - comA 1978269..1584 (+) -1976684 - - Regulator

Sequence

Protein


Download         Length: 721 a.a.        Molecular weight: 81336.61 Da        Isoelectric Point: 8.0981

>NTDB_id=910257 SO785_RS00005 WP_011254576.1 1978269..1584(+) (comA) [Lactobacillus acidophilus strain ATCC 4356]
MLLQYKSIYVPQVDESDCGVACLAMILKKYHSRVSLAHLRHSARTNLEGTTALGLVKTAQTFNLKTEAVKADMSLFDPDT
DIQYPFIVHVLKQGELLHYYVVLKATKNYLVIADPDPSVGLTKMSKEKFSQEWTGIALFMVPNDDFEPVKEKKRNLWSLF
PYMFKQKKLVTNIILAALLMTIISICSSYFLQGLIDTYIPNGTYQTLSILAIGLLIAYVFNSIFSYGQNFLLNILGQRLS
IDLNLQYIRHIFELPMEFFVTRRTGEITSRFSDASRIIDALASTVISLFLDLSIVIVMGIVLAIQNSTLFMITLLALPVY
AVVILSFSKKFEKLNNDQMESNAVLSSSVIEDIQGIETIKALNSEQTRYRKIDSQFVDYLKKSFRYSKTESLQSALKTFI
QLSLNVIILWVGAKVVMNGQMSIGQLMTFNALLSYFVDPLQSIINLQPTLQSANVAQNRLNEVYMVKSEFQKDVQIRDAK
QLVGDIEYHNVDYHYGYGVDVLKDVNLKIKQNDKLAIVGMSGSGKSTMVKLLVDFFSPSKGKLTFNGFDSTKVDKHVLRS
YVNYVPQTPYIFSGTIKENLLLGSRPDITEEDVLKACQIAEIESEIEQLPLQFETKMDENAKILSGGQKQRLTIARALLS
PAKVLIFDEATSGLDTITEKKVVDNLMKLKNKTIIFIAHRLAIAQRTNNIVVVDHGQIVEQGSHDELMQKHGFYYNLVEN

Nucleotide


Download         Length: 0 bp        

>NTDB_id=910257 SO785_RS00005 WP_011254576.1 1978269..1584(+) (comA) [Lactobacillus acidophilus strain ATCC 4356]

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(502-652)

ABC transporter transmembrane region (ABC_membrane)

(171-440)

Peptidase C39 family (Peptidase_C39)

(9-144)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q5FI74

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus mitis NCTC 12261

56.503

99.306

0.561
  comA Streptococcus pneumoniae Rx1

56.224

99.306

0.558
  comA Streptococcus pneumoniae D39

56.224

99.306

0.558
  comA Streptococcus pneumoniae R6

56.224

99.306

0.558
  comA Streptococcus mitis SK321

56.084

99.306

0.557
  comA Streptococcus pneumoniae TIGR4

56.084

99.306

0.557
  comA Streptococcus gordonii str. Challis substr. CH1

55.804

99.306

0.554
  comA/nlmT Streptococcus mutans UA159

54.096

98.333

0.532