Detailed information NTG0905487

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: SGQ71_RS09380
• Genome accession: NZ_CP138875
• Coordinates: 1919656..1920699 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain 11
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1914656..1925699

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SGQ71_RS09350 (SGQ71_09345)	-	1915077..1916333 (-)	1257	WP_075583716.1	aminopeptidase	-
SGQ71_RS09355 (SGQ71_09350)	-	1916336..1916536 (-)	201	WP_000180460.1	DUF1128 family protein	-
SGQ71_RS09360 (SGQ71_09355)	-	1916683..1917147 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
SGQ71_RS09365 (SGQ71_09360)	-	1917154..1917429 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
SGQ71_RS09370 (SGQ71_09365)	-	1917707..1918924 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
SGQ71_RS09375 (SGQ71_09370)	vraR	1919037..1919666 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
SGQ71_RS09380 (SGQ71_09375)	vraS	1919656..1920699 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
SGQ71_RS09385 (SGQ71_09380)	liaF	1920696..1921397 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
SGQ71_RS09390 (SGQ71_09385)	-	1921412..1921798 (-)	387	WP_001110179.1	hypothetical protein	-
SGQ71_RS09395 (SGQ71_09390)	map	1922015..1922773 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
SGQ71_RS09400 (SGQ71_09395)	-	1923302..1924288 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
SGQ71_RS09405 (SGQ71_09400)	-	1924719..1925132 (-)	414	WP_001670387.1	hypothetical protein	-
SGQ71_RS09410 (SGQ71_09405)	-	1925161..1925271 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=905487 SGQ71_RS09380 WP_001017131.1 1919656..1920699(-) (vraS) [Staphylococcus aureus strain 11]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=905487 SGQ71_RS09380 WP_001017131.1 1919656..1920699(-) (vraS) [Staphylococcus aureus strain 11]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1