Detailed information    

insolico Bioinformatically predicted

Overview

Name   comW   Type   Regulator
Locus tag   ABC810_RS11000 Genome accession   NZ_CP155532
Coordinates   2165001..2165237 (-) Length   78 a.a.
NCBI ID   WP_000939545.1    Uniprot ID   A0A0H2ZMA7
Organism   Streptococcus pneumoniae strain SP264     
Function   stabilization and activation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 2160001..2170237
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABC810_RS10970 (ABC810_10975) - 2160341..2161411 (+) 1071 WP_000401841.1 type I restriction endonuclease -
  ABC810_RS10975 (ABC810_10980) - 2161472..2161819 (+) 348 WP_001839379.1 hypothetical protein -
  ABC810_RS10980 (ABC810_10985) - 2161909..2162607 (+) 699 WP_001106362.1 site-specific integrase -
  ABC810_RS10990 (ABC810_10995) tadA 2162816..2163283 (-) 468 WP_000291870.1 tRNA adenosine(34) deaminase TadA -
  ABC810_RS10995 (ABC810_11000) - 2163484..2164770 (-) 1287 WP_000205044.1 adenylosuccinate synthase -
  ABC810_RS11000 (ABC810_11005) comW 2165001..2165237 (-) 237 WP_000939545.1 sigma(X)-activator ComW Regulator
  ABC810_RS11005 (ABC810_11010) - 2165503..2166300 (+) 798 Protein_2133 transposase -
  ABC810_RS11010 (ABC810_11015) - 2166335..2167181 (-) 847 Protein_2134 IS630 family transposase -

Sequence

Protein


Download         Length: 78 a.a.        Molecular weight: 9658.13 Da        Isoelectric Point: 6.7051

>NTDB_id=896754 ABC810_RS11000 WP_000939545.1 2165001..2165237(-) (comW) [Streptococcus pneumoniae strain SP264]
MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVRYGIGCRKDFIVYHYRVAYRLYLEKLVMNRGFISC

Nucleotide


Download         Length: 237 bp        

>NTDB_id=896754 ABC810_RS11000 WP_000939545.1 2165001..2165237(-) (comW) [Streptococcus pneumoniae strain SP264]
ATGTTACAAAAAATTTATGAGCAGATGGCTAATTTCTATGATAGTATTGAAGAAGAGTATGGTCCTACATTTGGTGATAA
TTTTGACTGGGAACATGTTCATTTTAAATTTTTAATTTATTATTTAGTGAGATATGGCATTGGTTGTCGTAAGGATTTTA
TTGTTTACCATTATCGTGTTGCTTATCGTTTGTATCTTGAAAAATTGGTAATGAATCGGGGGTTTATTTCTTGTTGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2ZMA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comW Streptococcus pneumoniae Rx1

100

100

1
  comW Streptococcus pneumoniae D39

100

100

1
  comW Streptococcus pneumoniae R6

100

100

1
  comW Streptococcus pneumoniae TIGR4

100

100

1
  comW Streptococcus mitis SK321

75.641

100

0.756
  comW Streptococcus mitis NCTC 12261

75.325

98.718

0.744