Detailed information NTG0896298

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: R4705_RS09885
• Genome accession: NZ_CP137115
• Coordinates: 1887243..1888196 (+)
• Length: 317 a.a.
• NCBI ID: WP_000495909.1
• Uniprot ID: A0A0H2UPP6
• Organism: Streptococcus pneumoniae strain 20614-6
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1882243..1893196

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R4705_RS09860	rpmG	1882986..1883135 (+)	150	WP_001809104.1	50S ribosomal protein L33	-
R4705_RS09865	secG	1883175..1883408 (+)	234	WP_000282517.1	preprotein translocase subunit SecG	-
R4705_RS09870	rnr	1883510..1885864 (+)	2355	WP_000654920.1	ribonuclease R	-
R4705_RS09875	smpB	1885827..1886294 (+)	468	WP_001051753.1	SsrA-binding protein SmpB	-
R4705_RS09880	tehB	1886310..1887170 (+)	861	WP_000413769.1	SAM-dependent methyltransferase TehB	-
R4705_RS09885	coiA	1887243..1888196 (+)	954	WP_000495909.1	competence protein CoiA	Machinery gene
R4705_RS09890	pepF	1888215..1890017 (+)	1803	WP_000244134.1	oligoendopeptidase F	Regulator
R4705_RS09895	-	1890019..1890732 (+)	714	WP_279513706.1	O-methyltransferase	-
R4705_RS09900	prsA	1890799..1891740 (+)	942	WP_000727935.1	peptidylprolyl isomerase PrsA	-
R4705_RS09905	-	1891859..1892200 (-)	342	Protein_1910	transposase	-
R4705_RS09910	-	1892613..1892708 (+)	96	Protein_1911	IS630 family transposase	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 38243.86 Da
• Isoelectric Point: 8.9865

>NTDB_id=896298 R4705_RS09885 WP_000495909.1 1887243..1888196(+) (coiA) [Streptococcus pneumoniae strain 20614-6]
MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTHFAHKSLKDCDFFFENESPEHLANKESLYHWLKKETK
VQLEYPLSELKQIADVFVNGNLALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTVSEDKDICRYIRQQLYYQNLFWM
KEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIEQDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE

Nucleotide

• Length: 954 bp

>NTDB_id=896298 R4705_RS09885 WP_000495909.1 1887243..1888196(+) (coiA) [Streptococcus pneumoniae strain 20614-6]
ATGTTTGTTGCGAGAGATGCTAGGGGAGAATTGGTAAATGTGTTAGAGGATAAACTTGAGAAGCAAGCATACACCTGCCC
AGCTTGTGGAGGCCAGCTCCATTTGCGTCAAGGACCAAGTGTACGGACGCATTTTGCCCATAAATCCTTAAAAGACTGTG
ATTTTTTCTTTGAAAATGAAAGTCCAGAACACCTGGCCAATAAGGAATCCCTCTATCACTGGTTGAAAAAAGAGACAAAG
GTTCAATTAGAGTACCCGCTTTCAGAACTTAAACAGATTGCGGATGTATTTGTAAATGGCAATCTAGCTCTAGAAGTTCA
GTGTAGTCCCTTGCCTCAGAAAGTCCTTAAAGAGCGAAGTGAGGGCTATCGTAGTCAGGGTTACCAAGTACTGTGGTTGC
TGGGTCAAAAACTGTGGCTCAAGGAGCGTTTGACTCGTCTACAGCAAGGTTTTCTTTATTTCAGTCAAAACATGGGCTTT
TATGTTTGGGAATTAGACAAGGAAAAACAAGTTTTAAGACTCAAATACCTGATTTACCAGGATCTCCGCGGTAAACTCCA
TTATCAAATCAAGGAATTTTCCTATGGTCAAGGTAGTTTATTGGAAATATTGCGTCTTCCCTATAAGAGACAAAAAATAT
CTCATTTTACAGTTTCTGAGGACAAGGACATCTGTCGCTATATCCGGCAACAACTTTATTATCAAAATCTCTTTTGGATG
AAAGAACAAGCAGAAGCCTATCAAAAGGGAGAAAATATCCTGACTTATGGACTGAAAGAATGGTATCCACAAATTCGACC
AATAGTGGGCAAATTTTTCCAGATTGAACAAGACTTGACTAGCTATTATCAGCACTTTTATACCTATTACCAAAAAAATC
CTCAAAATGATTGGCAAAAGCTTTATCCACCAGCCTTTTATCAGCAATATTTCTTGAAAAATATGGTAGAATAG

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (13-263)

3D structure

• AlphaFold DB: A0A0H2UPP6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus pneumoniae TIGR4	100	100	1
coiA	Streptococcus pneumoniae Rx1	99.369	100	0.994
coiA	Streptococcus pneumoniae D39	99.369	100	0.994
coiA	Streptococcus pneumoniae R6	99.369	100	0.994
coiA	Streptococcus mitis NCTC 12261	89.274	100	0.893
coiA	Lactococcus lactis subsp. cremoris KW2	42.593	100	0.435