Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   R4705_RS04705 Genome accession   NZ_CP137115
Coordinates   868114..868821 (+) Length   235 a.a.
NCBI ID   WP_000166477.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 20614-6     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IS/Tn 867002..867472 868114..868821 flank 642


Gene organization within MGE regions


Location: 867002..868821
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4705_RS04695 - 867002..867559 (-) 558 Protein_878 transposase -
  R4705_RS04700 - 867545..868030 (+) 486 WP_001821625.1 cupin domain-containing protein -
  R4705_RS04705 vicR 868114..868821 (+) 708 WP_000166477.1 response regulator transcription factor Regulator

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 27254.62 Da        Isoelectric Point: 6.6568

>NTDB_id=896262 R4705_RS04705 WP_000166477.1 868114..868821(+) (vicR) [Streptococcus pneumoniae strain 20614-6]
MTKQVLLVDDEEHILRLLDYHLSKEGFSTQLVTNGRKALALAETEPFDFILLDIMLPQLDGIEVCKRLRAKGIKTPIMMV
SAKSDEFDKVLALELGADDYLTKPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKAPQFIRTIRGYGYKFKEL

Nucleotide


Download         Length: 708 bp        

>NTDB_id=896262 R4705_RS04705 WP_000166477.1 868114..868821(+) (vicR) [Streptococcus pneumoniae strain 20614-6]
ATGACAAAACAAGTCTTATTAGTGGATGATGAAGAACACATTCTGAGATTGCTTGACTACCATTTAAGTAAGGAAGGCTT
TTCTACTCAATTGGTAACAAATGGACGGAAGGCCTTAGCTTTGGCAGAAACAGAACCCTTTGATTTTATCTTGCTTGATA
TCATGTTACCACAATTAGATGGCATAGAAGTTTGTAAGCGGCTGAGAGCCAAAGGCATCAAAACTCCAATTATGATGGTT
TCTGCGAAAAGTGATGAATTTGATAAGGTTTTGGCCTTGGAATTAGGGGCTGATGACTACCTGACCAAGCCTTTTAGCCC
TAGAGAATTGCTGGCACGTGTCAAGGCTGTCCTCAGGCGAACTAAAGGAGAACAAGAAGGAGATGATTCAGATAATATTG
CTGACGATTCTTGGCTATTTGGGACCTTGAAAGTATACCCTGAGCGTCATGAGGTCTACAAGGCGAATAAGTTACTGAGT
TTGACCCCAAAAGAATTTGAACTCTTGCTCTATCTTATGAAACATCCCAACATGACACTGACTAGAGAGCGTCTTTTGGA
ACGTATCTGGGGATATGACTTTGGGCAGGAAACACGTTTGGTGGACGTTCATATTGGTAAGTTGAGGGAAAAAATTGAAG
ACAATCCTAAAGCCCCTCAATTTATTCGAACCATTCGGGGTTATGGTTATAAGTTCAAGGAGTTATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-115)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(159-232)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

48.707

98.723

0.481
  micA Streptococcus pneumoniae Cp1015

47.845

98.723

0.472
  covR Lactococcus lactis subsp. lactis strain DGCC12653

41.202

99.149

0.409
  covR Streptococcus salivarius strain HSISS4

40.171

99.574

0.4