Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   R4701_RS07600 Genome accession   NZ_CP137114
Coordinates   1476845..1477504 (-) Length   219 a.a.
NCBI ID   WP_317805874.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 15P3054     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1471845..1482504
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4701_RS07570 - 1472025..1472624 (+) 600 WP_000169894.1 phosphoribosylanthranilate isomerase -
  R4701_RS07575 trpB 1472602..1473825 (+) 1224 WP_000331292.1 tryptophan synthase subunit beta -
  R4701_RS07580 trpA 1473818..1474594 (+) 777 WP_001127044.1 tryptophan synthase subunit alpha -
  R4701_RS07585 - 1474566..1474676 (-) 111 Protein_1450 prepilin peptidase -
  R4701_RS07590 - 1474896..1475627 (+) 732 WP_000934018.1 hypothetical protein -
  R4701_RS07595 - 1475642..1476793 (+) 1152 WP_000481754.1 XRE family transcriptional regulator -
  R4701_RS07600 cclA/cilC 1476845..1477504 (-) 660 WP_317805874.1 A24 family peptidase Machinery gene
  R4701_RS07605 - 1477574..1478020 (+) 447 WP_317805876.1 GNAT family N-acetyltransferase -
  R4701_RS07610 - 1478248..1479426 (-) 1179 WP_000175876.1 ROK family transcriptional regulator -
  R4701_RS07615 - 1479706..1480968 (+) 1263 WP_000413335.1 PTS sugar transporter subunit IIC -
  R4701_RS07620 - 1480971..1481867 (+) 897 WP_000825665.1 PEP phosphonomutase -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24845.09 Da        Isoelectric Point: 8.3782

>NTDB_id=896209 R4701_RS07600 WP_317805874.1 1476845..1477504(-) (cclA/cilC) [Streptococcus pneumoniae strain 15P3054]
MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLRPLDLIPILSQVFNRFCCRYCKVRYPVWYALFELGLG
LLFLLYSWELLSLSKVILITAGLTLGIYDFRHQKYPLLVWMTFHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLAACVIIFGKLLLV

Nucleotide


Download         Length: 660 bp        

>NTDB_id=896209 R4701_RS07600 WP_317805874.1 1476845..1477504(-) (cclA/cilC) [Streptococcus pneumoniae strain 15P3054]
ATGATTGATTTTTATTTTTTTCTCGTCGGGAGCATTCTAGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGCA
ATCCATTATCAGTTCAGCCAGTCACTGCGATTCCTGTCAGACTCGCTTGCGTCCCTTAGATTTGATTCCGATTCTCTCAC
AGGTCTTCAATCGCTTTTGCTGTCGCTACTGCAAGGTCCGCTATCCTGTCTGGTATGCCCTCTTTGAACTAGGCTTAGGA
CTCCTCTTTCTGCTTTACTCTTGGGAATTACTTTCCTTGAGTAAAGTCATCCTAATCACTGCTGGTTTGACCTTGGGCAT
CTACGACTTTCGCCATCAGAAATATCCCTTACTGGTCTGGATGACTTTCCACCTAATCCTAATAGCTTCCTCTGGCTGGA
ATCTGGTCATGGTCTCCTTCCTCATACTTGGAATTTTGGCTCATTTTATCGATATCCGCATGGGTGCAGGGGATTTCCTT
TTTTTAGCTTCTTGCGCTCTCGTCTTTAGCGTAACGGAGTTACTGATCTTGATTCAGTTCGCTTCTGCGACGGGTATCCT
GGCCTTTCTCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTGCTTGTGTGATTATTTTTG
GTAAGCTACTGCTTGTTTGA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-89)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus pneumoniae Rx1

99.087

100

0.991
  cclA/cilC Streptococcus pneumoniae D39

99.087

100

0.991
  cclA/cilC Streptococcus pneumoniae R6

99.087

100

0.991
  cclA/cilC Streptococcus pneumoniae TIGR4

94.064

100

0.941
  cclA/cilC Streptococcus mitis SK321

91.781

100

0.918
  cclA/cilC Streptococcus mitis NCTC 12261

86.758

100

0.868