Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFC/cflB   Type   Machinery gene
Locus tag   R4701_RS05420 Genome accession   NZ_CP137114
Coordinates   1071316..1071978 (+) Length   220 a.a.
NCBI ID   WP_000649971.1    Uniprot ID   A0A0B7MFB3
Organism   Streptococcus pneumoniae strain 15P3054     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1066316..1076978
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4701_RS05390 tnpB 1066858..1067208 (+) 351 WP_050308803.1 IS66 family insertion sequence element accessory protein TnpB -
  R4701_RS05395 - 1067231..1067539 (-) 309 Protein_1063 transposase -
  R4701_RS05400 - 1067512..1068050 (+) 539 Protein_1064 transposase -
  R4701_RS05405 cysK 1068125..1069045 (-) 921 WP_000029860.1 cysteine synthase A -
  R4701_RS05410 - 1069330..1069965 (-) 636 WP_000395739.1 YigZ family protein -
  R4701_RS05415 comFA/cflA 1070021..1071319 (+) 1299 WP_000867590.1 DEAD/DEAH box helicase Machinery gene
  R4701_RS05420 comFC/cflB 1071316..1071978 (+) 663 WP_000649971.1 ComF family protein Machinery gene
  R4701_RS05425 hpf 1072058..1072606 (+) 549 WP_000599104.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  R4701_RS05430 - 1072742..1074715 (+) 1974 WP_000715111.1 DHH family phosphoesterase -
  R4701_RS05435 rplI 1074712..1075164 (+) 453 WP_000864220.1 50S ribosomal protein L9 -
  R4701_RS05440 dnaB 1075208..1076560 (+) 1353 WP_000852486.1 replicative DNA helicase -
  R4701_RS05445 - 1076562..1076828 (+) 267 WP_001278167.1 Veg family protein -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 25241.10 Da        Isoelectric Point: 7.3688

>NTDB_id=896177 R4701_RS05420 WP_000649971.1 1071316..1071978(+) (comFC/cflB) [Streptococcus pneumoniae strain 15P3054]
MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEENCPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQ
AMKDFFSRYKFDGDFLLRKVFASFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSLVR

Nucleotide


Download         Length: 663 bp        

>NTDB_id=896177 R4701_RS05420 WP_000649971.1 1071316..1071978(+) (comFC/cflB) [Streptococcus pneumoniae strain 15P3054]
ATGAAGTGCTTGTTATGTGGGCAGACTATGAAGACTGTTTTAACTTTTAGTAGTCTCTTACTTCTGAGGAATGATGACTC
TTGTCTTTGTTCAGACTGTGATTCTACTTTTGAAAGAATTGGGGAAGAGAACTGTCCAAATTGTATGAAAACAGAGTTGT
CAACAAAGTGTCAAGATTGTCAACTTTGGTGTAAAGAGGGAGTTGAAGTCAGTCATAGAGCGATTTTTACTTACAATCAA
GCTATGAAGGATTTTTTCAGTCGGTATAAGTTTGATGGAGACTTCCTGTTAAGAAAAGTTTTCGCTTCATTTTTAAGTGA
GGAGTTGAAAAAGTACAAAGAGTATCAATTTGTTGTAATTCCCCTAAGTCCTGATAGATATGCTAATAGAGGATTTAATC
AGGTTGAGGGCTTGGTAGAGGCAGCAGGCTTTGAGTATCTGGATTTATTAGAGAAAAGAGAAGAGAGAGCCAGTTCTTCT
AAAAATCGTTCAGAGCGCTTGGGGACAGAACTTCCTTTCTTTATTAAAAGTGGAGTCACTATTCCTAAAAAAATCCTACT
TATAGATGATATCTATACTACAGGAGCAACTATAAATCGTGTTAAGAAACTGTTGGAAGAAGCTGGTGCTAAGGATGTAA
AAACATTTTCCCTTGTAAGATGA

Domains

Predicted by InterproScan.

Phosphoribosyl transferase domain (Pribosyltran)

(153-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7MFB3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFC/cflB Streptococcus pneumoniae TIGR4

100

100

1
  comFC/cflB Streptococcus pneumoniae Rx1

99.545

100

0.995
  comFC/cflB Streptococcus pneumoniae D39

99.545

100

0.995
  comFC/cflB Streptococcus pneumoniae R6

99.545

100

0.995
  comFC/cflB Streptococcus mitis NCTC 12261

91.818

100

0.918
  comFC/cflB Streptococcus mitis SK321

91.364

100

0.914