Detailed information NTG0896143

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: R4707_RS10560
• Genome accession: NZ_CP137113
• Coordinates: 2011622..2012575 (+)
• Length: 317 a.a.
• NCBI ID: WP_000495909.1
• Uniprot ID: A0A0H2UPP6
• Organism: Streptococcus pneumoniae strain ZGX
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 2006622..2017575

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R4707_RS10535	rpmG	2007365..2007514 (+)	150	WP_001810029.1	50S ribosomal protein L33	-
R4707_RS10540	secG	2007554..2007787 (+)	234	WP_000282517.1	preprotein translocase subunit SecG	-
R4707_RS10545	rnr	2007889..2010243 (+)	2355	WP_081542977.1	ribonuclease R	-
R4707_RS10550	smpB	2010206..2010673 (+)	468	WP_001051750.1	SsrA-binding protein SmpB	-
R4707_RS10555	tehB	2010689..2011549 (+)	861	WP_000413762.1	SAM-dependent methyltransferase TehB	-
R4707_RS10560	coiA	2011622..2012575 (+)	954	WP_000495909.1	competence protein CoiA	Machinery gene
R4707_RS10565	pepF	2012594..2014396 (+)	1803	WP_081542975.1	oligoendopeptidase F	Regulator
R4707_RS10570	-	2014398..2015111 (+)	714	WP_000230399.1	O-methyltransferase	-
R4707_RS10575	prsA	2015178..2016119 (+)	942	WP_000727935.1	peptidylprolyl isomerase PrsA	-
R4707_RS10580	-	2016238..2016579 (-)	342	Protein_2044	transposase	-
R4707_RS10585	-	2016992..2017087 (+)	96	Protein_2045	IS630 family transposase	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 38243.86 Da
• Isoelectric Point: 8.9865

>NTDB_id=896143 R4707_RS10560 WP_000495909.1 2011622..2012575(+) (coiA) [Streptococcus pneumoniae strain ZGX]
MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTHFAHKSLKDCDFFFENESPEHLANKESLYHWLKKETK
VQLEYPLSELKQIADVFVNGNLALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTVSEDKDICRYIRQQLYYQNLFWM
KEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIEQDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE

Nucleotide

• Length: 954 bp

>NTDB_id=896143 R4707_RS10560 WP_000495909.1 2011622..2012575(+) (coiA) [Streptococcus pneumoniae strain ZGX]
ATGTTTGTTGCGAGAGATGCTAGGGGAGAATTGGTAAATGTGTTAGAGGATAAACTTGAGAAGCAAGCATACACCTGCCC
AGCTTGTGGAGGCCAGCTCCATTTGCGTCAAGGACCAAGTGTACGGACGCATTTTGCCCATAAATCCTTAAAAGACTGTG
ATTTTTTCTTTGAAAATGAAAGTCCAGAACACCTGGCCAATAAGGAATCTCTCTATCACTGGTTGAAAAAAGAGACAAAG
GTTCAATTAGAGTACCCGCTTTCAGAACTTAAACAGATTGCGGATGTATTTGTAAATGGCAATCTTGCTCTAGAAGTTCA
GTGTAGTCCCTTGCCTCAGAAAGTCCTTAAAGAGCGAAGTGAGGGATATCGTAGTCAGGGTTACCAAGTACTGTGGTTGC
TGGGTCAAAAACTGTGGCTCAAGGAGCGTTTGACTCGTCTACAGCAAGGTTTTCTTTATTTCAGTCAAAACATGGGCTTT
TATGTTTGGGAATTAGACAAGGAAAAACAAGTTTTAAGACTCAAATACCTGATTTACCAGGATCTCCGCGGTAAACTCCA
TTATCAAATCAAGGAATTTTCCTATGGTCAAGGTAGTTTATTGGAAATATTGCGTCTTCCCTATAAGAGACAAAAAATAT
CTCATTTTACAGTTTCTGAGGACAAGGACATCTGTCGCTATATCCGGCAACAACTTTATTATCAAAATCTCTTTTGGATG
AAAGAACAAGCAGAAGCCTATCAAAAGGGAGAAAATATCCTGACTTATGGACTGAAAGAATGGTATCCACAAATTCGACC
AATAGTGGGCAAATTTTTCCAGATTGAACAAGACTTGACTAGCTATTATCAGCACTTTTATACCTATTACCAAAAAAATC
CTCAAAATGATTGGCAAAAGCTTTATCCACCAGCCTTTTATCAGCAATATTTCTTGAAAAATATGGTAGAATAG

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (13-263)

3D structure

• AlphaFold DB: A0A0H2UPP6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus pneumoniae TIGR4	100	100	1
coiA	Streptococcus pneumoniae Rx1	99.369	100	0.994
coiA	Streptococcus pneumoniae D39	99.369	100	0.994
coiA	Streptococcus pneumoniae R6	99.369	100	0.994
coiA	Streptococcus mitis NCTC 12261	89.274	100	0.893
coiA	Lactococcus lactis subsp. cremoris KW2	42.593	100	0.435