Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   R4707_RS08400 Genome accession   NZ_CP137113
Coordinates   1588630..1589367 (+) Length   245 a.a.
NCBI ID   WP_001219137.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain ZGX     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1583630..1594367
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4707_RS08365 - 1584572..1584799 (-) 228 WP_130884158.1 hypothetical protein -
  R4707_RS08370 - 1584961..1585248 (-) 288 WP_000777760.1 hypothetical protein -
  R4707_RS08375 - 1585258..1585668 (-) 411 WP_001278301.1 HIT family protein -
  R4707_RS08380 pptA 1585736..1586467 (+) 732 WP_000889923.1 ABC transporter ATP-binding protein Regulator
  R4707_RS08385 - 1586464..1587513 (+) 1050 WP_081543022.1 ABC transporter permease -
  R4707_RS08390 - 1587681..1588010 (-) 330 WP_000132583.1 hypothetical protein -
  R4707_RS08395 - 1588287..1588625 (+) 339 WP_000682136.1 LytTR family DNA-binding domain-containing protein -
  R4707_RS08400 comE/blpR 1588630..1589367 (+) 738 WP_001219137.1 LytTR family DNA-binding domain-containing protein Regulator
  R4707_RS08405 - 1589381..1590721 (+) 1341 WP_001099894.1 sensor histidine kinase -
  R4707_RS08410 blpC 1590765..1590920 (-) 156 WP_000358812.1 quorum-sensing system pheromone BlpC -
  R4707_RS08415 - 1590977..1592338 (-) 1362 WP_001069064.1 bacteriocin secretion accessory protein -

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28768.92 Da        Isoelectric Point: 6.2366

>NTDB_id=896132 R4707_RS08400 WP_001219137.1 1588630..1589367(+) (comE/blpR) [Streptococcus pneumoniae strain ZGX]
MRIFVLEDDFSQQTRIETTIEKLLKEHHITLSSFEVFGKPDQLLAEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRD
PYALIVFVTTHSEFMPLSFRYQVSALDYIDKALSAEEFESRIETALLYANGQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
LETSTRPHRVILYTKTDRLEFTASLEEVLKQEPRLLQCHRSFLINPANVVHLDKKEKLLFFPNGGSCLIARYKVREVSEA
INNLH

Nucleotide


Download         Length: 738 bp        

>NTDB_id=896132 R4707_RS08400 WP_001219137.1 1588630..1589367(+) (comE/blpR) [Streptococcus pneumoniae strain ZGX]
ATGAGAATATTTGTTTTAGAAGATGATTTTTCCCAACAGACTAGAATTGAAACGACGATTGAGAAACTCTTGAAGGAACA
TCATATCACTCTGAGTTCTTTTGAAGTTTTTGGTAAGCCAGATCAATTGCTGGCAGAGGTGCATGAGAAGGGGGCCCATC
AGCTATTCTTTTTGGATATTGAGATTCGAAATGAGGAGATGAAGGGTCTGGAAGTGGCTAGAAAGATTCGGGATCGGGAT
CCGTATGCCCTGATTGTCTTTGTGACGACTCACTCGGAGTTTATGCCCCTGTCCTTTCGCTACCAAGTGTCTGCTCTGGA
TTATATTGATAAGGCCCTTTCGGCAGAGGAGTTTGAATCTCGTATCGAGACAGCCCTCCTCTATGCCAATGGTCAAGACA
GTAAAAGTCTAGCGGAAGATTGCTTTTACTTTAAATCAAAATTTGCTCAATTCCAGTATCCTTTTAAAGAGGTTTACTAT
CTCGAAACGTCCACAAGACCCCATCGTGTTATTCTCTATACCAAGACAGACAGGCTGGAATTTACAGCGAGTCTAGAGGA
GGTTCTCAAGCAGGAGCCTCGTCTCTTGCAGTGCCATCGCTCTTTTCTCATCAATCCTGCCAATGTGGTGCATTTAGATA
AGAAAGAAAAACTGCTTTTCTTTCCCAATGGTGGAAGTTGTCTAATCGCGCGTTATAAGGTCAGGGAAGTGTCTGAGGCT
ATTAATAACTTACACTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-122)

LytTr DNA-binding domain (LytTR)

(151-241)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

53.441

100

0.539
  comE/comE1 Streptococcus equinus JB1

43.038

96.735

0.416
  comE/comE2 Streptococcus equinus JB1

38.43

98.776

0.38