Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   R4707_RS03385 Genome accession   NZ_CP137113
Coordinates   644695..645354 (+) Length   219 a.a.
NCBI ID   WP_001866459.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain ZGX     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 639695..650354
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4707_RS03360 - 640000..640317 (-) 318 WP_050221104.1 PTS sugar transporter subunit IIB -
  R4707_RS03365 - 640332..641228 (-) 897 WP_001865114.1 hypothetical protein -
  R4707_RS03370 - 641231..642493 (-) 1263 WP_000413342.1 PTS sugar transporter subunit IIC -
  R4707_RS03375 - 642773..643951 (+) 1179 WP_000175876.1 ROK family transcriptional regulator -
  R4707_RS03380 - 644179..644625 (-) 447 WP_000155414.1 GNAT family N-acetyltransferase -
  R4707_RS03385 cclA/cilC 644695..645354 (+) 660 WP_001866459.1 A24 family peptidase Machinery gene
  R4707_RS03390 - 645406..646557 (-) 1152 WP_000481750.1 ImmA/IrrE family metallo-endopeptidase -
  R4707_RS03395 - 646572..647303 (-) 732 WP_000934016.1 hypothetical protein -
  R4707_RS03400 - 647523..647633 (+) 111 Protein_672 prepilin peptidase -
  R4707_RS03405 trpA 647605..648381 (-) 777 WP_001127027.1 tryptophan synthase subunit alpha -
  R4707_RS03410 trpB 648374..649597 (-) 1224 WP_001865226.1 tryptophan synthase subunit beta -
  R4707_RS03415 - 649575..650174 (-) 600 WP_001865225.1 phosphoribosylanthranilate isomerase -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24827.91 Da        Isoelectric Point: 7.6166

>NTDB_id=896081 R4707_RS03385 WP_001866459.1 644695..645354(+) (cclA/cilC) [Streptococcus pneumoniae strain ZGX]
MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTPLRPLDLIPILSQVFNRFRCRYCKVRYPVWYALFELGLG
LLFLLYSWELLSLGQVVLITAGLTLSIYDFRHQEYPLLVWMTFHLILIASSGWNLVMVSFLALGILAHFIDIRMGAGDFL
FLASCALVFSITELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCVIIFGKLLLV

Nucleotide


Download         Length: 660 bp        

>NTDB_id=896081 R4707_RS03385 WP_001866459.1 644695..645354(+) (cclA/cilC) [Streptococcus pneumoniae strain ZGX]
ATGATTGATTTTTATTTTTTTCTCGTCGGGAGCATTCTCGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGCA
ATCCATTATCAGTTCAGCCAGTCACTGCGATTCCTGTCAGACTCCCTTGCGTCCCTTAGATTTGATTCCGATTCTCTCAC
AGGTCTTCAATCGCTTTCGCTGTCGCTACTGCAAGGTCCGCTATCCTGTCTGGTATGCCCTCTTTGAACTAGGCTTAGGA
CTCCTCTTTCTGCTTTACTCTTGGGAATTGCTTTCCTTGGGGCAAGTCGTCCTAATCACCGCTGGTTTGACCTTGAGCAT
CTATGACTTTCGCCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCACCTAATCCTAATAGCTTCCTCTGGCTGGA
ATCTGGTCATGGTCTCCTTCCTTGCTCTTGGAATTTTGGCTCATTTTATCGATATCCGCATGGGCGCAGGGGATTTCCTC
TTTTTAGCTTCTTGTGCTCTCGTCTTTAGCATAACGGAGTTACTGATCTTGATTCAGTTTGCTTCTGCGACGGGTATCCT
AGCCTTTCTCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTACCTTTCCTCTTACTTGCTACTTGTGTGATTATTTTTG
GTAAGCTACTGCTTGTCTGA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-89)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus pneumoniae Rx1

96.347

100

0.963
  cclA/cilC Streptococcus pneumoniae D39

96.347

100

0.963
  cclA/cilC Streptococcus pneumoniae R6

96.347

100

0.963
  cclA/cilC Streptococcus pneumoniae TIGR4

95.89

100

0.959
  cclA/cilC Streptococcus mitis SK321

93.151

100

0.932
  cclA/cilC Streptococcus mitis NCTC 12261

87.215

100

0.872