Detailed information NTG0896063

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: R4700_RS10105
• Genome accession: NZ_CP137112
• Coordinates: 1964796..1965749 (+)
• Length: 317 a.a.
• NCBI ID: WP_000495909.1
• Uniprot ID: A0A0H2UPP6
• Organism: Streptococcus pneumoniae strain 02H2025
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1959796..1970749

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R4700_RS10080	rpmG	1960539..1960688 (+)	150	WP_001809104.1	50S ribosomal protein L33	-
R4700_RS10085	secG	1960728..1960961 (+)	234	WP_000282517.1	preprotein translocase subunit SecG	-
R4700_RS10090	rnr	1961063..1963417 (+)	2355	WP_050119545.1	ribonuclease R	-
R4700_RS10095	smpB	1963380..1963847 (+)	468	WP_001051753.1	SsrA-binding protein SmpB	-
R4700_RS10100	tehB	1963863..1964723 (+)	861	WP_000413758.1	SAM-dependent methyltransferase TehB	-
R4700_RS10105	coiA	1964796..1965749 (+)	954	WP_000495909.1	competence protein CoiA	Machinery gene
R4700_RS10110	pepF	1965768..1967570 (+)	1803	WP_000244134.1	oligoendopeptidase F	Regulator
R4700_RS10115	-	1967572..1968285 (+)	714	WP_000230399.1	O-methyltransferase	-
R4700_RS10120	prsA	1968352..1969293 (+)	942	WP_317770876.1	peptidylprolyl isomerase PrsA	-
R4700_RS10125	-	1969412..1969753 (-)	342	Protein_1953	transposase	-
R4700_RS10130	-	1970166..1970261 (+)	96	Protein_1954	IS630 family transposase	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 38243.86 Da
• Isoelectric Point: 8.9865

>NTDB_id=896063 R4700_RS10105 WP_000495909.1 1964796..1965749(+) (coiA) [Streptococcus pneumoniae strain 02H2025]
MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTHFAHKSLKDCDFFFENESPEHLANKESLYHWLKKETK
VQLEYPLSELKQIADVFVNGNLALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTVSEDKDICRYIRQQLYYQNLFWM
KEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIEQDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE

Nucleotide

• Length: 954 bp

>NTDB_id=896063 R4700_RS10105 WP_000495909.1 1964796..1965749(+) (coiA) [Streptococcus pneumoniae strain 02H2025]
ATGTTTGTTGCGAGAGATGCTAGGGGAGAATTGGTAAATGTGTTAGAGGATAAACTTGAGAAGCAAGCATACACCTGCCC
AGCTTGTGGAGGCCAGCTCCATTTGCGTCAAGGACCAAGTGTACGGACGCATTTTGCCCATAAATCCTTAAAAGACTGTG
ATTTTTTCTTTGAAAATGAAAGTCCAGAACACCTGGCCAATAAGGAATCCCTCTATCACTGGTTGAAAAAAGAGACAAAG
GTTCAATTAGAGTACCCGCTTTCAGAACTTAAACAGATTGCGGATGTATTTGTAAATGGCAATCTAGCTCTAGAAGTTCA
GTGTAGTCCCTTGCCTCAGAAAGTCCTTAAAGAGCGAAGTGAGGGCTATCGTAGTCAGGGTTACCAAGTACTGTGGTTGC
TGGGTCAAAAACTGTGGCTCAAGGAGCGTTTGACTCGTCTACAGCAAGGTTTTCTTTATTTCAGTCAAAACATGGGCTTT
TATGTTTGGGAATTAGACAAGGAAAAACAAGTTTTAAGACTCAAATACCTGATTTACCAGGATCTCCGCGGTAAACTCCA
TTATCAAATCAAGGAATTTTCCTATGGTCAAGGTAGTTTATTGGAAATATTGCGTCTTCCCTATAAGAGACAAAAAATAT
CTCATTTTACAGTTTCTGAGGACAAGGACATCTGTCGCTATATCCGGCAACAACTTTATTATCAAAATCTCTTTTGGATG
AAAGAACAAGCAGAAGCCTATCAAAAGGGAGAAAATATCCTGACTTATGGACTGAAAGAATGGTATCCACAAATTCGACC
AATAGTGGGCAAATTTTTCCAGATTGAACAAGACTTGACTAGCTATTATCAGCACTTTTATACCTATTACCAAAAAAATC
CTCAAAATGATTGGCAAAAGCTTTATCCACCAGCCTTTTATCAGCAATATTTCTTGAAAAATATGGTAGAATAG

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (13-263)

3D structure

• AlphaFold DB: A0A0H2UPP6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus pneumoniae TIGR4	100	100	1
coiA	Streptococcus pneumoniae Rx1	99.369	100	0.994
coiA	Streptococcus pneumoniae D39	99.369	100	0.994
coiA	Streptococcus pneumoniae R6	99.369	100	0.994
coiA	Streptococcus mitis NCTC 12261	89.274	100	0.893
coiA	Lactococcus lactis subsp. cremoris KW2	42.593	100	0.435