Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   R4700_RS03185 Genome accession   NZ_CP137112
Coordinates   634339..634998 (+) Length   219 a.a.
NCBI ID   WP_277770837.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 02H2025     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 629339..639998
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4700_RS03160 - 629644..629961 (-) 318 WP_001151646.1 PTS sugar transporter subunit IIB -
  R4700_RS03165 - 629976..630872 (-) 897 WP_000825669.1 PEP phosphonomutase -
  R4700_RS03170 - 630875..632137 (-) 1263 WP_000413336.1 PTS sugar transporter subunit IIC -
  R4700_RS03175 - 632417..633595 (+) 1179 WP_000175880.1 ROK family transcriptional regulator -
  R4700_RS03180 - 633823..634269 (-) 447 WP_000155406.1 GNAT family N-acetyltransferase -
  R4700_RS03185 cclA/cilC 634339..634998 (+) 660 WP_277770837.1 A24 family peptidase Machinery gene
  R4700_RS03190 - 635050..636201 (-) 1152 WP_050096570.1 XRE family transcriptional regulator -
  R4700_RS03195 - 636216..636946 (-) 731 Protein_635 hypothetical protein -
  R4700_RS03200 - 637166..637276 (+) 111 Protein_636 prepilin peptidase -
  R4700_RS03205 trpA 637248..638024 (-) 777 WP_001126998.1 tryptophan synthase subunit alpha -
  R4700_RS03210 trpB 638017..639240 (-) 1224 WP_000331293.1 tryptophan synthase subunit beta -
  R4700_RS03215 - 639218..639811 (-) 594 WP_288160066.1 phosphoribosylanthranilate isomerase -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24891.10 Da        Isoelectric Point: 8.2409

>NTDB_id=896007 R4700_RS03185 WP_277770837.1 634339..634998(+) (cclA/cilC) [Streptococcus pneumoniae strain 02H2025]
MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLRPLDLIPILSQVFNRFRCRYCKIRYPVWYALFELVLG
LLFLLYSWKLLSLGQVVLITAGLTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLAACVIIFGKLLLV

Nucleotide


Download         Length: 660 bp        

>NTDB_id=896007 R4700_RS03185 WP_277770837.1 634339..634998(+) (cclA/cilC) [Streptococcus pneumoniae strain 02H2025]
ATGATTGATTTTTATTTTTTTCTCGTCGGGAGCATTCTCGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGCA
ATCCATTATCAGTTCAGCCAGTCACTGCGATTCCTGTCAGACTCGCTTGCGTCCCTTAGATTTGATTCCGATTCTCTCAC
AGGTCTTCAATCGCTTTCGCTGTCGCTACTGCAAAATTCGCTATCCTGTCTGGTATGCCCTCTTTGAATTAGTCTTAGGA
CTCCTCTTTCTGCTTTACTCTTGGAAATTGCTTTCCTTGGGGCAAGTCGTCCTAATCACCGCTGGTTTGACCTTGGGTAT
CTACGACTTTCACCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCACCTAATCCTAATAGCTTCCTCTGGCTGGA
ATCTGGTCATGGTCTCCTTCCTCATACTTGGAATTTTGGCTCATTTTATCGATATCCGCATGGGCGCAGGGGATTTCCTC
TTTTTAGCTTCTTGTGCTCTCGTCTTTAGCGTAACGGAGTTACTGATCTTGATTCAGTTTGCTTCTGCGACGGGTATCCT
GGCCTTTCTCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTGCTTGTGTGATTATTTTTG
GTAAGCTACTGCTTGTCTGA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-89)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus pneumoniae Rx1

96.804

100

0.968
  cclA/cilC Streptococcus pneumoniae D39

96.804

100

0.968
  cclA/cilC Streptococcus pneumoniae R6

96.804

100

0.968
  cclA/cilC Streptococcus pneumoniae TIGR4

96.347

100

0.963
  cclA/cilC Streptococcus mitis SK321

92.237

100

0.922
  cclA/cilC Streptococcus mitis NCTC 12261

86.758

100

0.868