Detailed information NTG0895991

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: R4706_RS10060
• Genome accession: NZ_CP137111
• Coordinates: 1971194..1972147 (+)
• Length: 317 a.a.
• NCBI ID: WP_000495909.1
• Uniprot ID: A0A0H2UPP6
• Organism: Streptococcus pneumoniae strain 17023
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1966194..1977147

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R4706_RS10035	rpmG	1966937..1967086 (+)	150	WP_001809104.1	50S ribosomal protein L33	-
R4706_RS10040	secG	1967126..1967359 (+)	234	WP_000282517.1	preprotein translocase subunit SecG	-
R4706_RS10045	rnr	1967461..1969815 (+)	2355	WP_044727641.1	ribonuclease R	-
R4706_RS10050	smpB	1969778..1970245 (+)	468	WP_001051750.1	SsrA-binding protein SmpB	-
R4706_RS10055	tehB	1970261..1971121 (+)	861	WP_000413758.1	SAM-dependent methyltransferase TehB	-
R4706_RS10060	coiA	1971194..1972147 (+)	954	WP_000495909.1	competence protein CoiA	Machinery gene
R4706_RS10065	pepF	1972166..1973968 (+)	1803	WP_044727642.1	oligoendopeptidase F	Regulator
R4706_RS10070	-	1973970..1974683 (+)	714	WP_000230399.1	O-methyltransferase	-
R4706_RS10075	prsA	1974750..1975691 (+)	942	WP_000727935.1	peptidylprolyl isomerase PrsA	-
R4706_RS10080	-	1975810..1976151 (-)	342	Protein_1943	transposase	-
R4706_RS10085	-	1976564..1976659 (+)	96	Protein_1944	IS630 family transposase	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 38243.86 Da
• Isoelectric Point: 8.9865

>NTDB_id=895991 R4706_RS10060 WP_000495909.1 1971194..1972147(+) (coiA) [Streptococcus pneumoniae strain 17023]
MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTHFAHKSLKDCDFFFENESPEHLANKESLYHWLKKETK
VQLEYPLSELKQIADVFVNGNLALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTVSEDKDICRYIRQQLYYQNLFWM
KEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIEQDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE

Nucleotide

• Length: 954 bp

>NTDB_id=895991 R4706_RS10060 WP_000495909.1 1971194..1972147(+) (coiA) [Streptococcus pneumoniae strain 17023]
ATGTTTGTTGCGAGAGATGCTAGGGGAGAATTGGTAAATGTGTTAGAGGATAAACTTGAGAAGCAAGCATACACCTGCCC
AGCTTGTGGAGGCCAGCTCCATTTGCGTCAAGGACCAAGTGTACGGACGCATTTTGCCCATAAATCCTTAAAAGACTGTG
ATTTTTTCTTTGAAAATGAAAGTCCAGAACACCTGGCCAATAAGGAATCCCTCTATCACTGGTTGAAAAAAGAGACAAAG
GTTCAATTAGAGTACCCGCTTTCAGAACTTAAACAGATTGCGGATGTATTTGTAAATGGCAATCTAGCTCTAGAAGTTCA
GTGTAGTCCCTTGCCTCAGAAAGTCCTTAAAGAGCGAAGTGAGGGCTATCGTAGTCAGGGTTACCAAGTACTGTGGTTGC
TGGGTCAAAAACTGTGGCTCAAGGAGCGTTTGACTCGTCTACAGCAAGGTTTTCTTTATTTCAGTCAAAACATGGGCTTT
TATGTTTGGGAATTAGACAAGGAAAAACAAGTTTTAAGACTCAAATACCTGATTTACCAGGATCTCCGCGGTAAACTCCA
TTATCAAATCAAGGAATTTTCCTATGGTCAAGGTAGTTTATTGGAAATATTGCGTCTTCCCTATAAGAGACAAAAAATAT
CTCATTTTACAGTTTCTGAGGACAAGGACATCTGTCGCTATATCCGGCAACAACTTTATTATCAAAATCTCTTTTGGATG
AAAGAACAAGCAGAAGCCTATCAAAAGGGAGAAAATATCCTGACTTATGGACTGAAAGAATGGTATCCACAAATTCGACC
AATAGTGGGCAAATTTTTCCAGATTGAACAAGACTTGACTAGCTATTATCAGCACTTTTATACCTATTACCAAAAAAATC
CTCAAAATGATTGGCAAAAGCTTTATCCACCAGCCTTTTATCAGCAATATTTCTTGAAAAATATGGTAGAATAG

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (13-263)

3D structure

• AlphaFold DB: A0A0H2UPP6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus pneumoniae TIGR4	100	100	1
coiA	Streptococcus pneumoniae Rx1	99.369	100	0.994
coiA	Streptococcus pneumoniae D39	99.369	100	0.994
coiA	Streptococcus pneumoniae R6	99.369	100	0.994
coiA	Streptococcus mitis NCTC 12261	89.274	100	0.893
coiA	Lactococcus lactis subsp. cremoris KW2	42.593	100	0.435