Detailed information NTG0895896

Bioinformatically predicted

Overview

• Name: cclA/cilC
• Type: Machinery gene
• Locus tag: R4712_RS07635
• Genome accession: NZ_CP137110
• Coordinates: 1481109..1481768 (-)
• Length: 219 a.a.
• NCBI ID: WP_000565001.1
• Uniprot ID: A0A0B7M7B9
• Organism: Streptococcus pneumoniae strain 16H2041
• Function: processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1476109..1486768

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R4712_RS07605	-	1476298..1476897 (+)	600	WP_044812425.1	phosphoribosylanthranilate isomerase	-
R4712_RS07610	trpB	1476875..1478098 (+)	1224	WP_000331292.1	tryptophan synthase subunit beta	-
R4712_RS07615	trpA	1478091..1478867 (+)	777	WP_001127010.1	tryptophan synthase subunit alpha	-
R4712_RS07620	-	1478839..1478976 (-)	138	Protein_1461	prepilin peptidase	-
R4712_RS07625	-	1479160..1479891 (+)	732	WP_000934017.1	hypothetical protein	-
R4712_RS07630	-	1479906..1481057 (+)	1152	WP_000481750.1	ImmA/IrrE family metallo-endopeptidase	-
R4712_RS07635	cclA/cilC	1481109..1481768 (-)	660	WP_000565001.1	A24 family peptidase	Machinery gene
R4712_RS07640	-	1481838..1482284 (+)	447	WP_044812424.1	GNAT family N-acetyltransferase	-
R4712_RS07645	-	1482357..1482596 (+)	240	WP_001005784.1	transposase	-
R4712_RS07650	-	1482706..1482909 (-)	204	WP_000109957.1	CsbD family protein	-
R4712_RS07655	-	1482940..1483548 (-)	609	WP_000064115.1	Asp23/Gls24 family envelope stress response protein	-
R4712_RS07660	-	1483587..1483757 (-)	171	WP_000455066.1	DUF2273 domain-containing protein	-
R4712_RS07665	amaP	1483769..1484335 (-)	567	WP_000030213.1	alkaline shock response membrane anchor protein AmaP	-
R4712_RS07670	-	1484419..1484583 (-)	165	WP_001809002.1	GlsB/YeaQ/YmgE family stress response membrane protein	-
R4712_RS07675	mgaSpn	1485026..1486507 (+)	1482	WP_001205281.1	virulence factor transcriptional regulator MgaSpn	-

Sequence

Protein

• Length: 219 a.a.
• Molecular weight: 24820.92 Da
• Isoelectric Point: 7.2761

>NTDB_id=895896 R4712_RS07635 WP_000565001.1 1481109..1481768(-) (cclA/cilC) [Streptococcus pneumoniae strain 16H2041]
MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTPLRPLDLIPILSQVFNRFRCRYCKVRYPVWYALFELGLG
LLFLLYSWELLSLGQVVLITAGLTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCLIIFGKLLLV

Nucleotide

• Length: 660 bp

>NTDB_id=895896 R4712_RS07635 WP_000565001.1 1481109..1481768(-) (cclA/cilC) [Streptococcus pneumoniae strain 16H2041]
ATGATTGATTTTTATTTTTTTCTCGTCGGGAGCATTCTAGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGCA
ATCCATTATCAGTTCAGCCAGTCACTGCGATTCCTGTCAGACTCCCTTGCGTCCCTTAGATTTGATTCCGATTCTCTCAC
AGGTCTTCAATCGCTTTCGCTGTCGCTACTGCAAAGTTCGCTATCCTGTCTGGTATGCCCTCTTTGAACTAGGCTTAGGA
CTCCTCTTTCTGCTTTACTCTTGGGAATTGCTTTCCTTGGGGCAAGTCGTCCTAATCACCGCTGGTTTGACCTTGGGTAT
CTACGACTTTCACCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCACCTAATCCTAATAGCTTCCTCTGGCTGGA
ATCTGGTCATGGTCTCCTTCCTCATACTTGGAATTTTGGCTCATTTTATTGATATCCGCATGGGTGCAGGGGATTTCCTC
TTTTTAGCTTCTTGTGCTCTCGTCTTTAGCGTAACGGAGTTACTGATCTTGATTCAGTTCGCTTCTGCGACGGGTATCCT
GGCCTTTCTCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTACTTGTTTGATTATTTTTG
GTAAGCTACTGCTTGTTTGA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (8-89)

3D structure

• AlphaFold DB: A0A0B7M7B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cclA/cilC	Streptococcus pneumoniae TIGR4	98.174	100	0.982
cclA/cilC	Streptococcus pneumoniae Rx1	96.804	100	0.968
cclA/cilC	Streptococcus pneumoniae D39	96.804	100	0.968
cclA/cilC	Streptococcus pneumoniae R6	96.804	100	0.968
cclA/cilC	Streptococcus mitis SK321	92.237	100	0.922
cclA/cilC	Streptococcus mitis NCTC 12261	87.215	100	0.872