Detailed information    

insolico Bioinformatically predicted

Overview


Name   comW   Type   Regulator
Locus tag   R4704_RS05745 Genome accession   NZ_CP137109
Coordinates   1096582..1096818 (+) Length   78 a.a.
NCBI ID   WP_000939548.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 11012     
Function   stabilization and activation of ComX (predicted from homology)   
Competence regulation

Genomic Context


Location: 1091582..1101818
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4704_RS05735 - 1095364..1095573 (+) 210 Protein_1084 transposase -
  R4704_RS05740 - 1095608..1096316 (-) 709 Protein_1085 transposase -
  R4704_RS05745 comW 1096582..1096818 (+) 237 WP_000939548.1 sigma(X)-activator ComW Regulator
  R4704_RS05750 - 1097049..1098335 (+) 1287 WP_000205044.1 adenylosuccinate synthase -
  R4704_RS05755 tadA 1098536..1099003 (+) 468 WP_000291874.1 tRNA adenosine(34) deaminase TadA -
  R4704_RS05765 - 1099190..1099633 (+) 444 WP_000701992.1 dUTP diphosphatase -
  R4704_RS05770 - 1099635..1100150 (+) 516 WP_000691236.1 histidine phosphatase family protein -
  R4704_RS05775 radA 1100164..1101525 (+) 1362 WP_074017595.1 DNA repair protein RadA Machinery gene

Sequence


Protein


Download         Length: 78 a.a.        Molecular weight: 9716.17 Da        Isoelectric Point: 6.7051

>NTDB_id=895811 R4704_RS05745 WP_000939548.1 1096582..1096818(+) (comW) [Streptococcus pneumoniae strain 11012]
MLQKIYEQMTNFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVRYGIGCRRDFIVYHYRVAYRLYLEKLVMNRGFISC

Nucleotide


Download         Length: 237 bp        

>NTDB_id=895811 R4704_RS05745 WP_000939548.1 1096582..1096818(+) (comW) [Streptococcus pneumoniae strain 11012]
ATGTTACAAAAAATTTATGAGCAGATGACTAATTTCTATGATAGTATTGAAGAAGAGTATGGTCCTACATTTGGTGATAA
TTTTGACTGGGAACATGTTCATTTTAAATTTTTAATTTATTATTTAGTGAGATATGGCATTGGTTGTCGTAGGGATTTTA
TCGTTTACCATTATCGTGTTGCTTATCGTTTGTATCTTGAAAAATTGGTAATGAATCGGGGTTTTATTTCTTGTTGA

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comW Streptococcus pneumoniae Rx1

97.436

100

0.974

  comW Streptococcus pneumoniae D39

97.436

100

0.974

  comW Streptococcus pneumoniae R6

97.436

100

0.974

  comW Streptococcus pneumoniae TIGR4

97.436

100

0.974

  comW Streptococcus mitis SK321

76.923

100

0.769

  comW Streptococcus mitis NCTC 12261

76.623

98.718

0.756