Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFC/cflB   Type   Machinery gene
Locus tag   R4711_RS05750 Genome accession   NZ_CP137107
Coordinates   1126952..1127614 (+) Length   220 a.a.
NCBI ID   WP_050263690.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 15H4024     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1121952..1132614
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4711_RS05720 tnpB 1122410..1122697 (+) 288 WP_000586646.1 IS66 family insertion sequence element accessory protein TnpB -
  R4711_RS05725 - 1122888..1123175 (-) 288 Protein_1130 transposase -
  R4711_RS05730 - 1123148..1123686 (+) 539 Protein_1131 transposase -
  R4711_RS05735 cysK 1123761..1124681 (-) 921 WP_000029860.1 cysteine synthase A -
  R4711_RS05740 - 1124966..1125601 (-) 636 WP_000395739.1 YigZ family protein -
  R4711_RS05745 comFA/cflA 1125657..1126955 (+) 1299 WP_050263689.1 DEAD/DEAH box helicase Machinery gene
  R4711_RS05750 comFC/cflB 1126952..1127614 (+) 663 WP_050263690.1 ComF family protein Machinery gene
  R4711_RS05755 hpf 1127694..1128242 (+) 549 WP_000599107.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  R4711_RS05760 - 1128378..1130357 (+) 1980 WP_050213963.1 DHH family phosphoesterase -
  R4711_RS05765 rplI 1130354..1130806 (+) 453 WP_000864220.1 50S ribosomal protein L9 -
  R4711_RS05770 dnaB 1130850..1132202 (+) 1353 WP_000852486.1 replicative DNA helicase -
  R4711_RS05775 - 1132204..1132470 (+) 267 WP_001278167.1 Veg family protein -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 25251.08 Da        Isoelectric Point: 7.3690

>NTDB_id=895635 R4711_RS05750 WP_050263690.1 1126952..1127614(+) (comFC/cflB) [Streptococcus pneumoniae strain 15H4024]
MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEENCPNCMKTELSTRCQDCQLWCKEGVEVSHRAIFTYNQ
AIKDFFSRYKFDGDFLLRKVFASFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSLVR

Nucleotide


Download         Length: 663 bp        

>NTDB_id=895635 R4711_RS05750 WP_050263690.1 1126952..1127614(+) (comFC/cflB) [Streptococcus pneumoniae strain 15H4024]
ATGAAGTGCTTGTTATGTGGGCAGACTATGAAGACTGTTTTAACTTTTAGTAGTCTCTTACTTCTGAGGAATGATGACTC
TTGTCTTTGTTCAGACTGTGATTCTACTTTTGAAAGAATTGGGGAAGAGAACTGTCCAAATTGTATGAAAACAGAGTTGT
CAACAAGGTGTCAAGACTGTCAACTTTGGTGTAAAGAAGGAGTTGAAGTCAGTCATAGAGCGATTTTTACTTACAATCAA
GCTATAAAGGATTTTTTCAGTCGGTATAAGTTTGATGGAGACTTCCTGTTAAGAAAAGTTTTCGCTTCATTTTTAAGTGA
GGAGTTGAAAAAGTACAAAGAGTATCAATTTGTTGTAATTCCCCTAAGTCCTGATAGATATGCTAACAGAGGATTTAATC
AGGTTGAGGGCTTGGTAGAGGCAGCAGGCTTTGAGTATCTGGATTTATTAGAGAAAAGAGAAGAGAGAGCCAGTTCTTCT
AAAAATCGTTCAGAGCGCTTGGGGACAGAACTTCCTTTCTTTATTAAAAGTGGAGTCACTATTCCTAAAAAAATCCTACT
TATAGATGATATCTATACTACAGGAGCAACTATAAATCGTGTTAAGAAACTGTTGGAAGAAGCTGGTGCTAAGGATGTAA
AAACATTTTCCCTTGTAAGATGA

Domains

Predicted by InterproScan.

Phosphoribosyl transferase domain (Pribosyltran)

(153-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFC/cflB Streptococcus pneumoniae TIGR4

99.091

100

0.991
  comFC/cflB Streptococcus pneumoniae Rx1

98.636

100

0.986
  comFC/cflB Streptococcus pneumoniae D39

98.636

100

0.986
  comFC/cflB Streptococcus pneumoniae R6

98.636

100

0.986
  comFC/cflB Streptococcus mitis NCTC 12261

90.909

100

0.909
  comFC/cflB Streptococcus mitis SK321

90.909

100

0.909