Detailed information    

insolico Bioinformatically predicted

Overview

Name   comW   Type   Regulator
Locus tag   R4711_RS05460 Genome accession   NZ_CP137107
Coordinates   1072336..1072572 (-) Length   78 a.a.
NCBI ID   WP_000939546.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 15H4024     
Function   stabilization and activation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1067336..1077572
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4711_RS05435 - 1067575..1067940 (+) 366 WP_050200267.1 helix-turn-helix domain-containing protein -
  R4711_RS05440 - 1067953..1068336 (+) 384 WP_050200266.1 ImmA/IrrE family metallo-endopeptidase -
  R4711_RS05445 - 1068348..1069256 (+) 909 WP_050200265.1 HIRAN domain-containing protein -
  R4711_RS05450 - 1069429..1070577 (+) 1149 WP_000876726.1 site-specific integrase -
  R4711_RS05455 - 1070819..1072105 (-) 1287 WP_001819018.1 adenylosuccinate synthase -
  R4711_RS05460 comW 1072336..1072572 (-) 237 WP_000939546.1 sigma(X)-activator ComW Regulator
  R4711_RS05465 - 1072838..1073647 (+) 810 Protein_1087 transposase -
  R4711_RS05470 - 1073682..1073891 (-) 210 Protein_1088 transposase -

Sequence

Protein


Download         Length: 78 a.a.        Molecular weight: 9686.14 Da        Isoelectric Point: 6.7051

>NTDB_id=895627 R4711_RS05460 WP_000939546.1 1072336..1072572(-) (comW) [Streptococcus pneumoniae strain 15H4024]
MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVRYGIGCRRDFIVYHYRVAYRLYLEKLVMNRGFISC

Nucleotide


Download         Length: 237 bp        

>NTDB_id=895627 R4711_RS05460 WP_000939546.1 1072336..1072572(-) (comW) [Streptococcus pneumoniae strain 15H4024]
ATGTTACAAAAAATTTATGAGCAGATGGCTAATTTCTATGATAGTATTGAAGAAGAGTATGGTCCTACATTTGGTGATAA
TTTTGACTGGGAACATGTTCATTTTAAATTTTTAATTTATTATTTAGTGAGATATGGCATTGGTTGTCGTAGGGATTTTA
TCGTTTACCATTATCGTGTTGCTTATCGTTTGTATCTTGAAAAATTGGTAATGAATCGGGGTTTTATTTCTTGTTGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comW Streptococcus pneumoniae Rx1

98.718

100

0.987
  comW Streptococcus pneumoniae D39

98.718

100

0.987
  comW Streptococcus pneumoniae R6

98.718

100

0.987
  comW Streptococcus pneumoniae TIGR4

98.718

100

0.987
  comW Streptococcus mitis SK321

76.923

100

0.769
  comW Streptococcus mitis NCTC 12261

76.623

98.718

0.756