Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilA/pilA1   Type   Machinery gene
Locus tag   LDO07_RS06595 Genome accession   NZ_AP024937
Coordinates   1221452..1221922 (+) Length   156 a.a.
NCBI ID   WP_143585821.1    Uniprot ID   -
Organism   Thermus thermophilus strain AK1     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1216452..1226922
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LDO07_RS06575 (TthAK1_12910) ilvC 1216943..1217956 (-) 1014 WP_223965548.1 ketol-acid reductoisomerase -
  LDO07_RS06580 (TthAK1_12920) ilvN 1217953..1218465 (-) 513 WP_223965549.1 acetolactate synthase small subunit -
  LDO07_RS06585 (TthAK1_12930) ilvB 1218462..1220150 (-) 1689 WP_223965550.1 biosynthetic-type acetolactate synthase large subunit -
  LDO07_RS06590 (TthAK1_12940) - 1220306..1221286 (-) 981 WP_018461695.1 YpdA family putative bacillithiol disulfide reductase -
  LDO07_RS06595 (TthAK1_12950) pilA/pilA1 1221452..1221922 (+) 471 WP_143585821.1 GspH/FimT family protein Machinery gene
  LDO07_RS06600 (TthAK1_12960) - 1221978..1222451 (+) 474 WP_223965551.1 GspH/FimT family protein -
  LDO07_RS06605 (TthAK1_12970) pilA/pilA2 1222469..1223029 (+) 561 WP_267461250.1 type II secretion system protein Machinery gene
  LDO07_RS06610 (TthAK1_12980) pilA/pilA3 1223026..1223727 (+) 702 WP_223965553.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  LDO07_RS06615 (TthAK1_12990) comZ 1223738..1225414 (+) 1677 WP_223965554.1 pilus assembly PilX N-terminal domain-containing protein Machinery gene
  LDO07_RS06620 (TthAK1_13000) - 1225635..1225985 (+) 351 WP_143585831.1 prepilin-type N-terminal cleavage/methylation domain-containing protein -
  LDO07_RS06625 (TthAK1_13010) - 1226234..1226614 (+) 381 WP_223965555.1 DUF1640 domain-containing protein -

Sequence

Protein


Download         Length: 156 a.a.        Molecular weight: 17032.82 Da        Isoelectric Point: 11.4446

>NTDB_id=89558 LDO07_RS06595 WP_143585821.1 1221452..1221922(+) (pilA/pilA1) [Thermus thermophilus strain AK1]
MTRRGLTLLELLLVLGLLGVLLGLALPLLSPNRLALDQAARSLAAQVTRARLEAIRRNAFVGLQVFTEEAGGYLLFVDQN
ANRRYDPGEEFGAVRFGQGEWARVRLDPERSTLGNMPLLFDPRGIPAKPITATLVLTSGSATRKVVISQQGRARVE

Nucleotide


Download         Length: 471 bp        

>NTDB_id=89558 LDO07_RS06595 WP_143585821.1 1221452..1221922(+) (pilA/pilA1) [Thermus thermophilus strain AK1]
ATGACGCGGCGGGGCCTTACCCTTTTGGAGCTCCTGCTGGTCTTGGGCCTCCTGGGGGTCCTCCTAGGGCTGGCCCTTCC
ACTTCTTTCCCCCAACCGCCTCGCCCTGGACCAGGCCGCCCGCTCCCTCGCCGCCCAGGTGACCCGGGCAAGGCTCGAGG
CCATCCGCCGGAACGCCTTCGTGGGCCTGCAGGTGTTCACCGAAGAAGCGGGGGGCTATCTGCTCTTCGTGGACCAAAAC
GCGAACCGCCGCTACGACCCCGGGGAGGAGTTCGGCGCGGTCCGCTTCGGCCAGGGAGAGTGGGCCAGGGTGCGTTTGGA
TCCCGAGAGGAGCACCCTCGGCAACATGCCCCTCCTCTTTGACCCCCGGGGCATCCCGGCCAAACCCATCACCGCCACCC
TGGTCCTCACCTCAGGGAGCGCCACCCGCAAGGTAGTTATCTCCCAACAGGGCCGGGCCCGGGTGGAGTGA

Domains

Predicted by InterproScan.

Type II transport protein GspH (GspH)

(39-151)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilA/pilA1 Thermus thermophilus HB27

92.913

81.41

0.756

Multiple sequence alignment