Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilA/pilA2   Type   Machinery gene
Locus tag   LDO07_RS06605 Genome accession   NZ_AP024937
Coordinates   1222469..1223029 (+) Length   186 a.a.
NCBI ID   WP_267461250.1    Uniprot ID   -
Organism   Thermus thermophilus strain AK1     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1217469..1228029
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LDO07_RS06580 (TthAK1_12920) ilvN 1217953..1218465 (-) 513 WP_223965549.1 acetolactate synthase small subunit -
  LDO07_RS06585 (TthAK1_12930) ilvB 1218462..1220150 (-) 1689 WP_223965550.1 biosynthetic-type acetolactate synthase large subunit -
  LDO07_RS06590 (TthAK1_12940) - 1220306..1221286 (-) 981 WP_018461695.1 YpdA family putative bacillithiol disulfide reductase -
  LDO07_RS06595 (TthAK1_12950) pilA/pilA1 1221452..1221922 (+) 471 WP_143585821.1 GspH/FimT family protein Machinery gene
  LDO07_RS06600 (TthAK1_12960) - 1221978..1222451 (+) 474 WP_223965551.1 GspH/FimT family protein -
  LDO07_RS06605 (TthAK1_12970) pilA/pilA2 1222469..1223029 (+) 561 WP_267461250.1 type II secretion system protein Machinery gene
  LDO07_RS06610 (TthAK1_12980) pilA/pilA3 1223026..1223727 (+) 702 WP_223965553.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  LDO07_RS06615 (TthAK1_12990) comZ 1223738..1225414 (+) 1677 WP_223965554.1 pilus assembly PilX N-terminal domain-containing protein Machinery gene
  LDO07_RS06620 (TthAK1_13000) - 1225635..1225985 (+) 351 WP_143585831.1 prepilin-type N-terminal cleavage/methylation domain-containing protein -
  LDO07_RS06625 (TthAK1_13010) - 1226234..1226614 (+) 381 WP_223965555.1 DUF1640 domain-containing protein -
  LDO07_RS06630 (TthAK1_13020) - 1226690..1227232 (+) 543 WP_223966753.1 Uma2 family endonuclease -
  LDO07_RS06635 (TthAK1_13030) - 1227222..1227434 (+) 213 WP_223965556.1 DUF2281 domain-containing protein -

Sequence

Protein


Download         Length: 186 a.a.        Molecular weight: 19639.32 Da        Isoelectric Point: 6.9027

>NTDB_id=89559 LDO07_RS06605 WP_267461250.1 1222469..1223029(+) (pilA/pilA2) [Thermus thermophilus strain AK1]
MEVLVALAVIGIAFAALLTSQLANLRANAQARFATDAKAAAVQVLERRSAEVLKSEIVPASSPYKDAPLDPDNPSGSWRS
FYFVDYYFSCPTPVAPSPKQRGGSVDNLRPGLTCSDTETVGDIPVAWSIRGESGILGEGVVTVVVTATHPRGPKVTMGRR
VTCYDVYPSPTQDQPAPCPPPGGGRP

Nucleotide


Download         Length: 561 bp        

>NTDB_id=89559 LDO07_RS06605 WP_267461250.1 1222469..1223029(+) (pilA/pilA2) [Thermus thermophilus strain AK1]
GTGGAAGTCCTTGTCGCCTTGGCCGTCATTGGAATCGCCTTTGCCGCCTTGTTGACGAGCCAGCTTGCCAACCTCCGGGC
GAACGCCCAGGCCCGCTTCGCCACCGACGCCAAGGCCGCCGCCGTCCAGGTCCTGGAGCGCCGCTCGGCCGAGGTGCTGA
AAAGCGAAATCGTCCCGGCCTCGAGCCCCTACAAGGACGCGCCCTTGGACCCTGATAACCCTTCGGGGAGCTGGCGGAGC
TTTTACTTCGTGGACTACTACTTCTCCTGCCCCACCCCGGTGGCCCCTTCCCCTAAGCAGCGGGGAGGGTCTGTAGACAA
CCTTCGCCCCGGCCTCACCTGCTCGGACACGGAGACGGTCGGGGACATCCCCGTGGCCTGGAGCATCCGCGGGGAAAGCG
GCATCCTGGGCGAGGGCGTGGTGACGGTGGTGGTCACGGCCACCCATCCCCGGGGGCCCAAGGTCACCATGGGCCGCCGG
GTCACCTGCTACGACGTCTACCCTTCCCCCACCCAGGACCAGCCCGCCCCCTGCCCGCCCCCGGGAGGTGGTCGCCCATG
A

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilA/pilA2 Thermus thermophilus HB27

90.449

95.699

0.866

Multiple sequence alignment