Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFC/cflB   Type   Machinery gene
Locus tag   R4702_RS05615 Genome accession   NZ_CP137106
Coordinates   1102607..1103269 (+) Length   220 a.a.
NCBI ID   WP_000649974.1    Uniprot ID   A0A0F7YBW3
Organism   Streptococcus pneumoniae strain 16P4028     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1097607..1108269
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4702_RS05585 tnpB 1098065..1098352 (+) 288 WP_000586646.1 IS66 family insertion sequence element accessory protein TnpB -
  R4702_RS05590 - 1098543..1098830 (-) 288 Protein_1107 transposase -
  R4702_RS05595 - 1098803..1099341 (+) 539 Protein_1108 transposase -
  R4702_RS05600 cysK 1099416..1100336 (-) 921 WP_000029866.1 cysteine synthase A -
  R4702_RS05605 - 1100621..1101256 (-) 636 WP_000395739.1 YigZ family protein -
  R4702_RS05610 comFA/cflA 1101312..1102610 (+) 1299 WP_000867605.1 DEAD/DEAH box helicase Machinery gene
  R4702_RS05615 comFC/cflB 1102607..1103269 (+) 663 WP_000649974.1 ComF family protein Machinery gene
  R4702_RS05620 hpf 1103349..1103897 (+) 549 WP_000599104.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  R4702_RS05625 - 1104033..1106006 (+) 1974 WP_000715111.1 DHH family phosphoesterase -
  R4702_RS05630 rplI 1106003..1106455 (+) 453 WP_000864220.1 50S ribosomal protein L9 -
  R4702_RS05635 dnaB 1106499..1107851 (+) 1353 WP_050205400.1 replicative DNA helicase -
  R4702_RS05640 - 1107853..1108119 (+) 267 WP_001278167.1 Veg family protein -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 25169.03 Da        Isoelectric Point: 7.7116

>NTDB_id=895556 R4702_RS05615 WP_000649974.1 1102607..1103269(+) (comFC/cflB) [Streptococcus pneumoniae strain 16P4028]
MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEENCPNCMKTELSTKCQDCQLWCKEGVGVSHRAIFTYNQ
AMKDFFSRYKFDGDFLLRKVFASFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSLVR

Nucleotide


Download         Length: 663 bp        

>NTDB_id=895556 R4702_RS05615 WP_000649974.1 1102607..1103269(+) (comFC/cflB) [Streptococcus pneumoniae strain 16P4028]
ATGAAGTGCTTGTTATGTGGGCAGACTATGAAGACTGTTTTAACTTTTAGTAGTCTCTTACTTCTGAGGAATGATGACTC
TTGTCTTTGTTCAGACTGTGATTCTACTTTTGAAAGAATTGGGGAAGAGAACTGTCCAAATTGTATGAAAACAGAGTTGT
CAACAAAGTGTCAAGACTGTCAACTTTGGTGTAAAGAAGGAGTTGGAGTCAGTCATAGAGCGATTTTTACTTACAATCAA
GCTATGAAGGATTTTTTCAGTCGGTATAAGTTTGATGGAGACTTCCTGTTAAGAAAAGTTTTCGCTTCATTTTTAAGTGA
GGAGTTGAAAAAGTACAAAGAGTATCAATTTGTTGTAATTCCCCTAAGTCCTGATAGATATGCTAATAGAGGATTTAATC
AGGTTGAGGGCTTGGTAGAGGCAGCAGGCTTTGAGTATCTGGATTTATTAGAGAAAAGAGAAGAGAGAGCCAGTTCTTCT
AAAAATCGTTCAGAGCGCTTGGGGACAGAACTTCCTTTCTTTATTAAAAGTGGAGTCACTATTCCTAAAAAAATCCTACT
TATAGATGATATCTATACTACAGGAGCAACTATAAATCGTGTTAAGAAACTGTTGGAAGAAGCTGGTGCTAAGGATGTAA
AAACATTTTCCCTTGTAAGATGA

Domains

Predicted by InterproScan.

Phosphoribosyl transferase domain (Pribosyltran)

(153-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0F7YBW3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFC/cflB Streptococcus pneumoniae Rx1

100

100

1
  comFC/cflB Streptococcus pneumoniae D39

100

100

1
  comFC/cflB Streptococcus pneumoniae R6

100

100

1
  comFC/cflB Streptococcus pneumoniae TIGR4

99.545

100

0.995
  comFC/cflB Streptococcus mitis NCTC 12261

91.364

100

0.914
  comFC/cflB Streptococcus mitis SK321

90.909

100

0.909