Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   R4699_RS03510 Genome accession   NZ_CP137105
Coordinates   690529..691878 (+) Length   449 a.a.
NCBI ID   WP_050104987.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 16H2092     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 685529..696878
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4699_RS03485 coaB 685684..686373 (-) 690 WP_000699495.1 phosphopantothenate--cysteine ligase -
  R4699_RS03490 - 686603..688273 (+) 1671 WP_000845292.1 formate--tetrahydrofolate ligase -
  R4699_RS03495 - 688379..688504 (-) 126 WP_001818232.1 hypothetical protein -
  R4699_RS03500 mutY 688601..689776 (+) 1176 WP_000886152.1 A/G-specific adenine glycosylase -
  R4699_RS03505 micA 689832..690536 (+) 705 WP_000722076.1 response regulator YycF Regulator
  R4699_RS03510 micB 690529..691878 (+) 1350 WP_050104987.1 cell wall metabolism sensor histidine kinase VicK Regulator
  R4699_RS03515 vicX 691880..692689 (+) 810 WP_001289493.1 MBL fold metallo-hydrolase Regulator
  R4699_RS03520 relB 692780..693022 (+) 243 WP_024477795.1 type II toxin-antitoxin system RelB family antitoxin -
  R4699_RS03525 - 693024..693278 (+) 255 WP_001809704.1 type II toxin-antitoxin system RelE/ParE family toxin -
  R4699_RS03530 - 693325..694098 (+) 774 WP_050104986.1 potassium channel family protein -
  R4699_RS03535 - 694361..695347 (-) 987 WP_000204727.1 L-lactate dehydrogenase -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 51712.42 Da        Isoelectric Point: 4.9706

>NTDB_id=895475 R4699_RS03510 WP_050104987.1 690529..691878(+) (micB) [Streptococcus pneumoniae strain 16H2092]
MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQINQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSE
VIRLTQENLEQESKRINSILFYMTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALC
ETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATSHLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIW
MEIDTDKMTQVVDNILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSRAQGGTGLG
LSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=895475 R4699_RS03510 WP_050104987.1 690529..691878(+) (micB) [Streptococcus pneumoniae strain 16H2092]
ATGCTTGATTTACTGAAACAAACCATTTTTACCAGAGATTTTATCTTTATCCTGATTTTGTTAGGTTTCATCCTTGTTGT
GACCCTCTTATTACTGGAAAATAGACGTGATAATATTCAGTTGAAGCAAATCAATCAAAAGGTTAAAGATTTGATTGCAG
GAGATTATTCCAAGGTTCTTGATATGCAAGGTGGGTCTGAAATCACCAATATTACCAATAATTTGAATGACTTGTCGGAG
GTTATTCGTCTCACTCAGGAAAATCTAGAACAAGAGAGTAAGAGGATAAATAGTATTCTGTTTTATATGACAGATGGGGT
TCTTGCGACCAACCGTCGGGGTCAGATTATCATGATTAACGATACAGCCAAGAAGCAACTGGGGTTGGTTAAGGAAGATG
TTCTGAATAGAAGCATTTTGGAATTGCTCAAGATAGAAGAAAACTATGAATTGCGTGATTTGATTACCCAAAGTCCAGAA
TTGTTGCTAGATTCCCAAGATATCAATGGCGAATATTTGAACCTTCGAGTTCGCTTTGCCTTGATACGTCGAGAGTCTGG
CTTTATTTCAGGTTTGGTGGCTGTTTTGCATGATACGACGGAGCAGGAGAAGGAAGAACGCGAACGAAGACTCTTTGTTT
CCAATGTTAGCCATGAGTTACGGACTCCTCTGACTAGCGTAAAATCCTATCTTGAAGCCTTGGATGAGGGGGCTTTGTGT
GAAACTGTAGCACCAGACTTTATCAAGGTTTCTCTTGATGAGACCAACCGTATGATGCGCATGGTGACGGATCTCCTCCA
TCTTTCACGTATTGATAATGCTACCAGTCACCTAGATGTGGAACTGATTAACTTCACTGCTTTTATTACCTTTATCCTCA
ATCGTTTTGACAAGATGAAAGGACAGGAAAAGGAGAAAAAATATGAGTTGGTGAGAGATTATCCCATCAATTCTATCTGG
ATGGAAATTGATACAGATAAGATGACGCAGGTTGTCGACAATATTTTAAATAATGCTATTAAGTATTCGCCAGATGGGGG
TAAAATCACTGTCAGAATGAAGACAACTGAAGACCAGATGATTTTATCCATTTCTGACCACGGTTTGGGGATTCCTAAGC
AGGATTTACCACGTATCTTTGACCGTTTCTATCGTGTGGATCGTGCTAGAAGTCGTGCACAAGGTGGTACAGGTCTAGGA
CTGTCTATCGCTAAAGAAATTATCAAACAACATAAGGGCTTTATTTGGGCCAAGAGTGAATACGGCAAGGGTTCAACCTT
TACCATTGTGCTCCCTTATGATAAGGATGCAGTGAAAGAAGAAGTATGGGAGGATGAAGTAGAAGACTAG

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

PAS fold (PAS)

(102-198)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

99.555

100

0.996
  vicK Streptococcus mutans UA159

69.652

89.532

0.624