Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicX   Type   Regulator
Locus tag   R4699_RS03515 Genome accession   NZ_CP137105
Coordinates   691880..692689 (+) Length   269 a.a.
NCBI ID   WP_001289493.1    Uniprot ID   Q9RCS5
Organism   Streptococcus pneumoniae strain 16H2092     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 686880..697689
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4699_RS03495 - 688379..688504 (-) 126 WP_001818232.1 hypothetical protein -
  R4699_RS03500 mutY 688601..689776 (+) 1176 WP_000886152.1 A/G-specific adenine glycosylase -
  R4699_RS03505 micA 689832..690536 (+) 705 WP_000722076.1 response regulator YycF Regulator
  R4699_RS03510 micB 690529..691878 (+) 1350 WP_050104987.1 cell wall metabolism sensor histidine kinase VicK Regulator
  R4699_RS03515 vicX 691880..692689 (+) 810 WP_001289493.1 MBL fold metallo-hydrolase Regulator
  R4699_RS03520 relB 692780..693022 (+) 243 WP_024477795.1 type II toxin-antitoxin system RelB family antitoxin -
  R4699_RS03525 - 693024..693278 (+) 255 WP_001809704.1 type II toxin-antitoxin system RelE/ParE family toxin -
  R4699_RS03530 - 693325..694098 (+) 774 WP_050104986.1 potassium channel family protein -
  R4699_RS03535 - 694361..695347 (-) 987 WP_000204727.1 L-lactate dehydrogenase -

Sequence

Protein


Download         Length: 269 a.a.        Molecular weight: 29916.89 Da        Isoelectric Point: 6.1743

>NTDB_id=895476 R4699_RS03515 WP_001289493.1 691880..692689(+) (vicX) [Streptococcus pneumoniae strain 16H2092]
MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLLAEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMD
LYANEKTWQAMENSKYLGKVDSSQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKKIYLGHLSKENNIKELAHMTMVN
QLAQADLGVGVDFKVYDTSPDTATPLTEI

Nucleotide


Download         Length: 810 bp        

>NTDB_id=895476 R4699_RS03515 WP_001289493.1 691880..692689(+) (vicX) [Streptococcus pneumoniae strain 16H2092]
ATGAGTGAAATAGGCTTTAAATACAGTATTTTAGCGTCGGGTTCCAGTGGAAATTCTTTTTATCTGGAAACCTCAAAAAA
GAAGCTTTTAGTAGATGCAGGCTTGTCTGGCAAGAAAATTACCAGTCTGCTAGCTGAAATTAACCGTAAGCCAGAAGACC
TGGATGCCATCTTGATTACCCATGAGCATTCAGATCATATCCATGGAGTAGGCGTTTTGGCTCGCAAGTATGGTATGGAT
CTTTATGCCAATGAAAAGACCTGGCAAGCTATGGAAAATAGTAAATATCTTGGCAAGGTGGATTCTTCGCAAAAGCATAT
TTTTGAAATGGGTAAAACCAAAACCTTTGGAGATATCGACATCGAGAGTTTTGGTGTAAGCCATGATGCAGTCGCACCGC
AGTTCTATCGCTTTATGAAGGATGATAAGAGTTTTGTCCTCTTGACAGATACAGGTTATGTCAGTGACCGTATGGCGGGC
ATTGTCGAAAATGCGGATGGTTATCTTATCGAGGCCAACCATGATGTAGAGATTTTGCGATCAGGTTCTTACGCTTGGCG
ACTCAAACAACGAATCCTATCTGACCTTGGTCACCTTTCTAACGAGGACGGTGCTGAAGCTATGATTCGGACGCTAGGAA
ATCGTACTAAGAAGATTTACCTTGGGCATTTATCTAAGGAAAACAATATCAAGGAACTGGCTCATATGACCATGGTCAAT
CAGCTGGCTCAAGCTGATCTGGGAGTCGGAGTAGACTTTAAGGTTTATGATACCTCACCAGATACCGCAACACCATTGAC
AGAGATATAG

Domains

Predicted by InterproScan.

Metallo-beta-lactamase superfamily (Lactamase_B)

(15-223)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9RCS5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicX Streptococcus mutans UA159

77.323

100

0.773