Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   R4699_RS00960 Genome accession   NZ_CP137105
Coordinates   167401..168060 (-) Length   219 a.a.
NCBI ID   WP_000565005.1    Uniprot ID   A0A0B7LMM1
Organism   Streptococcus pneumoniae strain 16H2092     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 162401..173060
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4699_RS00930 - 162581..163180 (+) 600 WP_000169913.1 phosphoribosylanthranilate isomerase -
  R4699_RS00935 trpB 163158..164381 (+) 1224 WP_000331292.1 tryptophan synthase subunit beta -
  R4699_RS00940 trpA 164374..165150 (+) 777 WP_001127044.1 tryptophan synthase subunit alpha -
  R4699_RS00945 - 165122..165226 (-) 105 Protein_166 prepilin peptidase -
  R4699_RS00950 - 165452..166183 (+) 732 WP_044727940.1 hypothetical protein -
  R4699_RS00955 - 166198..167349 (+) 1152 WP_000481754.1 XRE family transcriptional regulator -
  R4699_RS00960 cclA/cilC 167401..168060 (-) 660 WP_000565005.1 A24 family peptidase Machinery gene
  R4699_RS00965 - 168130..168576 (+) 447 WP_000155422.1 GNAT family N-acetyltransferase -
  R4699_RS00970 - 168804..169982 (-) 1179 WP_000175876.1 ROK family transcriptional regulator -
  R4699_RS00975 - 170262..171524 (+) 1263 WP_000413345.1 PTS sugar transporter subunit IIC -
  R4699_RS00980 - 171527..172423 (+) 897 WP_000825664.1 PEP phosphonomutase -
  R4699_RS00985 - 172438..172755 (+) 318 WP_050105030.1 PTS sugar transporter subunit IIB -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24846.03 Da        Isoelectric Point: 7.8950

>NTDB_id=895463 R4699_RS00960 WP_000565005.1 167401..168060(-) (cclA/cilC) [Streptococcus pneumoniae strain 16H2092]
MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLRPLDLIPILSQVFNRFCCRYCKVRYPVWYALFELGLG
LLFLLYSWELLSLSKVILITAGLTLGIYDFRHQEYPLLVWMTFHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLAACVIIFGKLLLV

Nucleotide


Download         Length: 660 bp        

>NTDB_id=895463 R4699_RS00960 WP_000565005.1 167401..168060(-) (cclA/cilC) [Streptococcus pneumoniae strain 16H2092]
ATGATTGATTTTTATTTTTTTCTCGTCGGGAGCATTCTAGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGCA
ATCCATTATCAGTTCAGCCAGTCACTGCGATTCCTGTCAGACTCGCTTGCGTCCCTTAGATTTGATTCCGATTCTCTCAC
AGGTCTTCAATCGCTTTTGCTGTCGCTACTGCAAGGTCCGCTATCCTGTCTGGTATGCCCTCTTTGAACTAGGCTTAGGA
CTCCTCTTTCTGCTTTACTCTTGGGAATTACTTTCCTTGAGTAAAGTCATCCTAATCACTGCTGGTTTGACCTTGGGCAT
CTACGACTTTCGCCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCACCTAATCCTAATAGCTTCCTCTGGCTGGA
ATCTGGTCATGGTCTCCTTCCTCATACTTGGAATTTTGGCTCATTTTATCGATATCCGCATGGGTGCAGGGGATTTCCTT
TTTTTAGCTTCTTGCGCTCTCGTCTTTAGCGTAACGGAGTTACTGATCTTGATTCAGTTCGCTTCTGCGACGGGTATCCT
GGCCTTTCTCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTGCTTGTGTGATTATTTTTG
GTAAGCTACTGCTTGTTTGA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-89)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7LMM1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus pneumoniae Rx1

99.543

100

0.995
  cclA/cilC Streptococcus pneumoniae D39

99.543

100

0.995
  cclA/cilC Streptococcus pneumoniae R6

99.543

100

0.995
  cclA/cilC Streptococcus pneumoniae TIGR4

94.521

100

0.945
  cclA/cilC Streptococcus mitis SK321

92.237

100

0.922
  cclA/cilC Streptococcus mitis NCTC 12261

87.215

100

0.872