Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   R4709_RS06485 Genome accession   NZ_CP137102
Coordinates   1265553..1266506 (+) Length   317 a.a.
NCBI ID   WP_044813830.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 16H3071-2     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1260553..1271506
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4709_RS06440 - 1260611..1260976 (+) 366 WP_000286415.1 DUF1033 family protein -
  R4709_RS06445 comGA/cglA/cilD 1261052..1261993 (+) 942 WP_000249567.1 competence type IV pilus ATPase ComGA Machinery gene
  R4709_RS06450 comGB/cglB 1261941..1262957 (+) 1017 WP_078132972.1 competence type IV pilus assembly protein ComGB Machinery gene
  R4709_RS06455 comGC/cglC 1262959..1263285 (+) 327 WP_000738625.1 competence type IV pilus major pilin ComGC Machinery gene
  R4709_RS06460 comGD/cglD 1263278..1263682 (+) 405 WP_000588030.1 competence type IV pilus minor pilin ComGD Machinery gene
  R4709_RS06465 comGE/cglE 1263645..1263947 (+) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  R4709_RS06470 comGF/cglF 1263910..1264371 (+) 462 WP_000250539.1 competence type IV pilus minor pilin ComGF Machinery gene
  R4709_RS06475 comGG/cglG 1264349..1264795 (+) 447 WP_001811371.1 competence type IV pilus minor pilin ComGG Machinery gene
  R4709_RS06480 - 1264898..1265492 (+) 595 Protein_1266 class I SAM-dependent methyltransferase -
  R4709_RS06485 comYH 1265553..1266506 (+) 954 WP_044813830.1 class I SAM-dependent methyltransferase Machinery gene
  R4709_RS06490 - 1266557..1267747 (+) 1191 WP_050085692.1 acetate kinase -
  R4709_RS06495 - 1267748..1267879 (+) 132 WP_000768904.1 hypothetical protein -
  R4709_RS06500 rnpA 1267896..1268267 (+) 372 WP_000739246.1 ribonuclease P protein component -
  R4709_RS06505 - 1268242..1269066 (+) 825 WP_000727904.1 membrane protein insertase YidC -
  R4709_RS06510 jag 1269085..1270071 (+) 987 WP_000260015.1 RNA-binding cell elongation regulator Jag/EloR -
  R4709_RS06515 - 1270122..1270745 (+) 624 WP_277779671.1 HI_0552 family protein -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 35688.93 Da        Isoelectric Point: 4.2952

>NTDB_id=895266 R4709_RS06485 WP_044813830.1 1265553..1266506(+) (comYH) [Streptococcus pneumoniae strain 16H3071-2]
MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGETELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQT
EPLQANHQFTPDAIALLLVFIVEELFKEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEMDDLLIDLAASMADVIGLQ
AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGLKYLKSDGYAIFLAPSDLLTSPQ
SNLLKVWLKEEASLVAMISLPENLFANAKQSKTIFILQKKSEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI

Nucleotide


Download         Length: 954 bp        

>NTDB_id=895266 R4709_RS06485 WP_044813830.1 1265553..1266506(+) (comYH) [Streptococcus pneumoniae strain 16H3071-2]
ATGGATTTTGAAAAAATTGAACAAGCCTATACCTATTTACTAGAGAATGTCCAAGTCATCCAAAGTGATTTGGCGACCAA
CTTTTATGACGCCTTGGTGGAGCAAAACAGCATCTATCTGGATGGTGAAACTGAGCTAAACCAGGTCAAAGACAACAATC
AGGCCCTTAAGCGTTTAGCACTACGCAAAGAAGAATGGCTCAAGACCTACCAGTTTCTCTTGATGAAGGCTGGGCAAACA
GAACCCTTGCAGGCCAATCACCAGTTTACACCAGATGCCATTGCTTTGCTTTTGGTGTTTATTGTGGAAGAGTTGTTTAA
AGAGGAGGAAATTACTATCCTCGAAATGGGTTCTGGGATGGGAATTCTAGGCGCTACTTTCTTGACCTCGCTTGATAAAA
AGGTGGATTACTTGGGAATGGAAATGGATGATTTGCTGATTGATCTGGCAGCTAGCATGGCAGATGTAATTGGTTTGCAG
GCTGGCTTTGTCCAAGGAGATGCCGTTCGTCCACAAATGCTCAAAGAAAGCGATGTGGTCATCAGTGACTTGCCTGTCGG
CTATTATCCTGATGACGCCGTTGCGTCGCGCCATCAAGTTGCTTCTAGTCAAGAACATACTTACGCCCATCACTTGCTCA
TGGAACAAGGACTTAAGTACCTCAAGTCAGACGGATACGCTATTTTTCTAGCTCCGAGTGATTTGTTGACCAGTCCTCAA
AGTAATTTGTTGAAAGTCTGGTTGAAAGAGGAGGCAAGTCTGGTTGCTATGATTAGTTTACCTGAAAATCTCTTTGCTAA
TGCTAAACAATCTAAGACTATTTTTATCCTACAGAAGAAAAGTGAAATAGCAGTGGAGCCTTTTGTTTATCCACTTGCTA
GCTTGCAAGATGCAAGTGTTTTAATGAAATTTAAAGAAAATTTTCAAAAATGGACTCAAGGTACTGAAATATAA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(69-282)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA140

54.633

98.738

0.539
  comYH Streptococcus mutans UA159

54.313

98.738

0.536