Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   LDO80_RS01560 Genome accession   NZ_AP024933
Coordinates   273394..274398 (-) Length   334 a.a.
NCBI ID   WP_224065420.1    Uniprot ID   -
Organism   Thermus thermophilus strain AA3-7     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 268394..279398
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LDO80_RS01525 (TthAA37_02990) hisG 268861..269481 (+) 621 WP_060384772.1 ATP phosphoribosyltransferase -
  LDO80_RS01530 (TthAA37_03000) trmH 269478..270062 (+) 585 WP_143584516.1 tRNA (guanosine(18)-2'-O)-methyltransferase TrmH -
  LDO80_RS01535 (TthAA37_03010) - 270052..270291 (-) 240 WP_008630920.1 hypothetical protein -
  LDO80_RS01540 (TthAA37_03020) - 270293..270481 (-) 189 WP_038034982.1 hypothetical protein -
  LDO80_RS01545 (TthAA37_03030) - 270471..271427 (-) 957 WP_143584518.1 branched-chain amino acid transaminase -
  LDO80_RS01550 (TthAA37_03050) - 271414..272372 (-) 959 Protein_300 LysR substrate-binding domain-containing protein -
  LDO80_RS01555 (TthAA37_03060) - 272482..273390 (+) 909 WP_143584525.1 manganese catalase family protein -
  LDO80_RS01560 (TthAA37_03070) dprA 273394..274398 (-) 1005 WP_224065420.1 DNA-processing protein DprA Machinery gene
  LDO80_RS01565 (TthAA37_03080) era 274483..275388 (+) 906 WP_008630929.1 GTPase Era -
  LDO80_RS01570 (TthAA37_03090) - 275433..276320 (+) 888 WP_143584533.1 acyltransferase -
  LDO80_RS01580 (TthAA37_03100) - 276516..277490 (+) 975 WP_143584535.1 DHH family phosphoesterase -
  LDO80_RS01585 (TthAA37_03110) - 277468..278016 (-) 549 WP_223965896.1 Uma2 family endonuclease -
  LDO80_RS01590 (TthAA37_03120) - 278026..279246 (-) 1221 WP_143584541.1 2,3-bisphosphoglycerate-independent phosphoglycerate mutase -

Sequence

Protein


Download         Length: 334 a.a.        Molecular weight: 36040.76 Da        Isoelectric Point: 5.8416

>NTDB_id=89522 LDO80_RS01560 WP_224065420.1 273394..274398(-) (dprA) [Thermus thermophilus strain AA3-7]
MDPLALALLPGIGPKRLLEVLKAEDPLGFLRERFPEAWRHLPEAEAQAERERGRAEALGVRILGLWEEDFPEGLKALPQP
PTHLYLKGELPPEREAVALVGTRRASPWALAFARRLARELSEAGLWVVSGLARGIDREAHLGALEAGGRTLGVLGSALDR
VYPPENRPLAQRMDLLSEFPFGTGPKPEFFPRRNRLIAGLSRAVVVVEAPLDSGALITARHALELGKEVLAVPGRPTDER
SLGANRLIQDGAYPVLSAEDVLAYLGVAARPKPLPGLSPEEEALYALLQEKGEALPEALAMALGIPPERVLSLLTLLELK
GLARALPGGRYGPG

Nucleotide


Download         Length: 1005 bp        

>NTDB_id=89522 LDO80_RS01560 WP_224065420.1 273394..274398(-) (dprA) [Thermus thermophilus strain AA3-7]
GTGGACCCCTTGGCCCTCGCCCTCCTCCCGGGCATCGGCCCCAAGCGGCTTTTGGAGGTCCTAAAGGCGGAGGACCCTCT
GGGCTTCCTGCGGGAGCGCTTCCCCGAGGCCTGGCGGCACCTCCCCGAAGCCGAGGCCCAGGCGGAAAGGGAAAGGGGGC
GCGCCGAGGCCCTGGGGGTGCGCATCCTGGGCCTCTGGGAGGAGGACTTCCCCGAGGGTCTGAAGGCGCTTCCCCAGCCG
CCCACCCACCTCTACCTGAAGGGGGAGCTTCCCCCGGAAAGGGAGGCGGTGGCCCTCGTGGGCACGCGCCGGGCCTCTCC
TTGGGCCTTGGCCTTTGCCCGGAGGCTCGCCCGGGAGCTTTCCGAGGCCGGGCTTTGGGTGGTCTCGGGCCTCGCCCGGG
GCATAGACCGGGAGGCCCACCTCGGGGCCCTCGAGGCCGGGGGGCGCACCCTGGGCGTCCTGGGAAGCGCCCTGGACCGG
GTCTACCCCCCGGAAAACCGCCCTTTGGCCCAACGGATGGACCTCCTCTCCGAGTTCCCCTTCGGGACCGGCCCTAAGCC
CGAGTTCTTTCCCCGGCGGAACCGCCTCATCGCCGGGCTCTCCCGGGCGGTGGTCGTGGTGGAGGCCCCCCTGGACTCCG
GGGCCCTCATCACCGCCCGCCACGCCTTGGAGCTCGGCAAGGAGGTGCTGGCCGTCCCCGGAAGGCCCACGGACGAGCGT
TCCCTGGGGGCCAACCGCCTCATCCAGGACGGGGCCTACCCGGTGCTCTCCGCCGAGGACGTCCTTGCCTACCTGGGGGT
GGCCGCAAGGCCCAAACCCCTCCCGGGCCTCTCCCCGGAGGAGGAGGCCCTTTACGCCCTCCTGCAGGAAAAGGGGGAGG
CGCTCCCCGAGGCCCTGGCCATGGCCCTGGGGATCCCCCCGGAGCGGGTGCTCTCCCTCCTCACCCTCTTGGAGCTAAAG
GGCCTGGCCCGGGCCCTCCCGGGAGGGCGCTACGGGCCAGGCTAA

Domains

Predicted by InterproScan.

DprA winged helix domain (DprA_WH)

(268-329)

DNA recombination-mediator protein A (DNA_processg_A)

(56-255)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Thermus thermophilus HB27

97.006

100

0.97
  dprA Vibrio campbellii strain DS40M4

38.547

100

0.413
  dprA Vibrio cholerae strain A1552

37.569

100

0.407
  dprA Deinococcus radiodurans R1 = ATCC 13939 = DSM 20539

45.205

87.425

0.395
  dprA Neisseria meningitidis strain C311

37.725

100

0.377
  dprA Neisseria meningitidis MC58

37.725

100

0.377

Multiple sequence alignment