Detailed information    

insolico Bioinformatically predicted

Overview

Name   coiA   Type   Machinery gene
Locus tag   R4710_RS10450 Genome accession   NZ_CP137101
Coordinates   1991519..1992472 (+) Length   317 a.a.
NCBI ID   WP_000495909.1    Uniprot ID   A0A0H2UPP6
Organism   Streptococcus pneumoniae strain 16P2012-2     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IScluster/Tn 1990099..1996667 1991519..1992472 within 0


Gene organization within MGE regions


Location: 1990099..1996667
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4710_RS10445 - 1990099..1991355 (-) 1257 WP_288166553.1 ISL3 family transposase -
  R4710_RS10450 coiA 1991519..1992472 (+) 954 WP_000495909.1 competence protein CoiA Machinery gene
  R4710_RS10455 pepF 1992491..1994293 (+) 1803 WP_050245207.1 oligoendopeptidase F Regulator
  R4710_RS10460 - 1994295..1995008 (+) 714 WP_000230399.1 O-methyltransferase -
  R4710_RS10465 prsA 1995075..1996016 (+) 942 WP_050245208.1 peptidylprolyl isomerase PrsA -
  R4710_RS10470 - 1996135..1996476 (-) 342 Protein_2029 transposase -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 38243.86 Da        Isoelectric Point: 8.9865

>NTDB_id=895219 R4710_RS10450 WP_000495909.1 1991519..1992472(+) (coiA) [Streptococcus pneumoniae strain 16P2012-2]
MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTHFAHKSLKDCDFFFENESPEHLANKESLYHWLKKETK
VQLEYPLSELKQIADVFVNGNLALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTVSEDKDICRYIRQQLYYQNLFWM
KEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIEQDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE

Nucleotide


Download         Length: 954 bp        

>NTDB_id=895219 R4710_RS10450 WP_000495909.1 1991519..1992472(+) (coiA) [Streptococcus pneumoniae strain 16P2012-2]
ATGTTTGTTGCGAGAGATGCTAGGGGAGAATTGGTAAATGTGTTAGAGGATAAACTTGAGAAGCAAGCATACACCTGCCC
AGCTTGTGGAGGCCAGCTCCATTTGCGTCAAGGACCAAGTGTACGGACGCATTTTGCCCATAAATCCTTAAAAGACTGTG
ATTTTTTCTTTGAAAATGAAAGTCCAGAACACCTGGCCAATAAGGAATCCCTCTATCACTGGTTGAAAAAAGAGACAAAG
GTTCAATTAGAGTACCCGCTTTCAGAACTTAAACAGATTGCGGATGTATTTGTAAATGGCAATCTAGCTCTAGAAGTTCA
GTGTAGTCCCTTGCCTCAGAAAGTCCTTAAAGAGCGAAGTGAGGGATATCGTAGTCAGGGTTACCAAGTACTGTGGTTGC
TGGGTCAAAAACTGTGGCTCAAGGAGCGTTTGACTCGTCTACAGCAAGGTTTTCTTTATTTCAGTCAAAACATGGGCTTT
TATGTTTGGGAATTAGACAAGGAAAAACAAGTTTTAAGACTCAAATACCTGATTTACCAGGATCTCCGCGGTAAACTCCA
TTATCAAATCAAGGAATTTTCCTATGGTCAAGGTAGTTTATTGGAAATATTGCGTCTTCCCTATAAGAGACAAAAAATAT
CTCATTTTACAGTTTCTGAGGACAAGGACATCTGTCGCTATATCCGGCAACAACTTTATTATCAAAATCTCTTTTGGATG
AAAGAACAAGCAGAAGCCTATCAAAAGGGAGAAAATATCCTGACTTATGGACTGAAAGAATGGTATCCACAAATTCGACC
AATAGTGGGCAAATTTTTCCAGATTGAACAAGACTTGACTAGCTATTATCAGCACTTTTATACCTATTACCAAAAAAATC
CTCAAAATGATTGGCAAAAGCTTTATCCACCAGCCTTTTATCAGCAATATTTCTTGAAAAATATGGTAGAATAG

Domains

Predicted by InterproScan.

Competence protein CoiA-like family (CoiA_nuc)

(13-263)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UPP6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  coiA Streptococcus pneumoniae TIGR4

100

100

1
  coiA Streptococcus pneumoniae Rx1

99.369

100

0.994
  coiA Streptococcus pneumoniae D39

99.369

100

0.994
  coiA Streptococcus pneumoniae R6

99.369

100

0.994
  coiA Streptococcus mitis NCTC 12261

89.274

100

0.893
  coiA Lactococcus lactis subsp. cremoris KW2

42.593

100

0.435