Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   R4710_RS08400 Genome accession   NZ_CP137101
Coordinates   1592735..1594411 (-) Length   558 a.a.
NCBI ID   WP_306423909.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 16P2012-2     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1587735..1599411
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4710_RS08370 - 1588067..1588396 (-) 330 WP_000132583.1 hypothetical protein -
  R4710_RS08375 - 1588673..1589011 (+) 339 WP_000682124.1 LytTR family DNA-binding domain-containing protein -
  R4710_RS08380 comE/blpR 1589016..1589753 (+) 738 WP_001219139.1 response regulator transcription factor Regulator
  R4710_RS08385 - 1589767..1591107 (+) 1341 WP_317804516.1 sensor histidine kinase -
  R4710_RS08390 blpC 1591151..1591306 (-) 156 WP_000358811.1 quorum-sensing system pheromone BlpC -
  R4710_RS08395 - 1591363..1592724 (-) 1362 WP_001069064.1 bacteriocin secretion accessory protein -
  R4710_RS08400 comA/nlmT 1592735..1594411 (-) 1677 WP_306423909.1 peptide cleavage/export ABC transporter Regulator
  R4710_RS08405 comA/nlmT 1594305..1594892 (-) 588 WP_050245347.1 cysteine peptidase family C39 domain-containing protein Regulator
  R4710_RS08410 blpM 1595182..1595436 (+) 255 WP_050245346.1 two-peptide bacteriocin subunit BlpM -
  R4710_RS08415 blpN 1595452..1595655 (+) 204 WP_001099490.1 two-peptide bacteriocin subunit BlpN -
  R4710_RS08420 cipB 1595899..1596048 (+) 150 WP_001809846.1 bacteriocin-like peptide BlpO Regulator
  R4710_RS11280 - 1596084..1596149 (+) 66 Protein_1621 ComC/BlpC family peptide pheromone/bacteriocin -
  R4710_RS08425 - 1596152..1596271 (+) 120 WP_000346296.1 PncF family bacteriocin immunity protein -
  R4710_RS08430 - 1596739..1597110 (+) 372 WP_404969402.1 hypothetical protein -
  R4710_RS08435 - 1597271..1598240 (+) 970 Protein_1624 thioredoxin domain-containing protein -
  R4710_RS08440 - 1598487..1598720 (+) 234 WP_033705506.1 bacteriocin class II family protein -

Sequence

Protein


Download         Length: 558 a.a.        Molecular weight: 62978.29 Da        Isoelectric Point: 7.1280

>NTDB_id=895208 R4710_RS08400 WP_306423909.1 1592735..1594411(-) (comA/nlmT) [Streptococcus pneumoniae strain 16P2012-2]
MIFKQKSLIAYIVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYILQQVMSFSRDYLLTVLSQRLSI
DVILSYIRHIFELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLLSIPIYM
FIIFSFMKPFEKMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQTSLKQGTK
LVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVESEFQVQENPVHSHF
LMGDIEFDDLSYKYGFGRDTLTDINLTIKQGDKVSLVGVSGSGKTTLAKMIVNFFKPYKGHISINHQDIKNIDKKVLRRH
INYLPQQAYIFNGSILENLTLGGNHMISQEDILKAYELAEIRQDIERMPMGYQTQLSDGAGLSGGQKQRIALARALLTKS
PVLILDEATSGLDVLTEKKVIDNLISLTDKTILFVAHRLSIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK

Nucleotide


Download         Length: 1677 bp        

>NTDB_id=895208 R4710_RS08400 WP_306423909.1 1592735..1594411(-) (comA/nlmT) [Streptococcus pneumoniae strain 16P2012-2]
CTGATTTTCAAACAAAAATCTCTCATTGCTTACATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATAGGTGGTTC
TTACTATCTCCAAGGAATCTTGGATGAGTACATTCCAAATCAGATGAAATCAACTTTAGGAATCATCTCAGTTGGTCTGG
TTATCACCTATATCCTCCAACAAGTCATGAGCTTCTCCAGAGATTATCTCCTAACCGTTCTGAGCCAGAGATTAAGCATT
GATGTGATTTTATCCTATATTCGCCATATTTTTGAACTTCCCATGTCTTTCTTTGCGACACGTCGTACAGGAGAAATCAT
TTCACGGTTCACAGATGCTAACTCTATTATAGATGCCTTGGCTTCTACCATTCTTTCTCTTTTTCTGGATGTTTCTATTC
TGATTCTTGTAGGGGGAGTCTTGCTGGCACAAAACCCTAATCTCTTCCTCCTTTCTCTTCTTTCCATTCCTATATACATG
TTCATCATCTTTTCTTTTATGAAACCTTTTGAAAAAATGAACCATGATGTCATGCAAAGTAATTCTATGGTTAGCTCTGC
CATTATCGAAGATATCAACGGGATTGAAACTATAAAGTCGCTCACGAGTGAAGAAAATCGCTATCAAAATATAGACAGCG
AATTTGTAGATTATTTGGAAAAATCCTTTAAGCTCAGTAAATATTCTATTTTACAAACGAGTTTAAAGCAGGGAACAAAA
TTAGTTCTGAATATCCTTATCCTATGGTTTGGCGCTCAATTAGTCATGTCGAGTAAAATTTCTATCGGTCAGCTGATTAC
CTTTAACACACTTTTTTCTTACTTTACAACTCCTATGGAAAATATTATCAACCTCCAAACCAAACTCCAATCTGCGAAGG
TCGCTAATAACCGTTTGAACGAAGTCTATCTAGTCGAATCTGAATTTCAAGTTCAAGAAAACCCTGTTCATTCACATTTT
TTGATGGGCGATATTGAATTTGATGACCTTTCTTATAAGTATGGTTTTGGACGAGATACCTTAACAGATATTAATCTCAC
GATTAAACAAGGAGATAAGGTTAGCCTAGTTGGAGTTAGTGGTTCTGGTAAAACAACTTTAGCCAAAATGATTGTCAATT
TCTTTAAACCCTACAAAGGGCATATTTCCATCAATCATCAGGATATTAAAAACATTGATAAAAAAGTCTTGCGCCGTCAT
ATTAATTACCTACCCCAACAAGCCTATATCTTTAATGGCTCTATTTTGGAAAACTTAACCTTGGGCGGTAATCATATGAT
TAGCCAAGAAGATATTCTAAAAGCTTATGAATTAGCTGAAATTCGTCAAGACATTGAAAGAATGCCTATGGGCTATCAAA
CTCAGCTCTCTGATGGAGCTGGTCTATCAGGAGGACAAAAGCAACGAATCGCTCTCGCTCGTGCTCTTTTAACTAAATCT
CCTGTTTTAATACTAGACGAAGCTACTAGCGGTCTTGATGTCTTGACTGAGAAAAAGGTTATAGATAATCTTATATCCCT
AACTGATAAAACCATTCTCTTTGTAGCCCATCGTCTCAGTATAGCCGAACGAACTAACCGTGTCATTGTTCTTGACCAGG
GGAAAATCATTGAAGTTGGTAGTCACCAAGAGTTAATGCAGGCGCAAGGCTTCTACCATCATCTATTCAATAAATAA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(341-490)

ABC transporter transmembrane region (ABC_membrane)

(10-279)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

72.531

99.821

0.724
  comA Streptococcus pneumoniae Rx1

67.204

100

0.672
  comA Streptococcus pneumoniae D39

67.204

100

0.672
  comA Streptococcus pneumoniae R6

67.204

100

0.672
  comA Streptococcus mitis NCTC 12261

67.204

100

0.672
  comA Streptococcus pneumoniae TIGR4

66.846

100

0.668
  comA Streptococcus mitis SK321

66.667

100

0.667
  comA Streptococcus gordonii str. Challis substr. CH1

66.547

100

0.667