Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   R4703_RS03285 Genome accession   NZ_CP137100
Coordinates   616526..617185 (+) Length   219 a.a.
NCBI ID   WP_000565027.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain LYP     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 611526..622185
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4703_RS03260 - 611831..612148 (-) 318 WP_001151646.1 PTS sugar transporter subunit IIB -
  R4703_RS03265 - 612163..613059 (-) 897 WP_000825667.1 PEP phosphonomutase -
  R4703_RS03270 - 613062..614324 (-) 1263 WP_000413336.1 PTS sugar transporter subunit IIC -
  R4703_RS03275 - 614604..615782 (+) 1179 WP_000175880.1 ROK family transcriptional regulator -
  R4703_RS03280 - 616010..616456 (-) 447 WP_000155408.1 GNAT family N-acetyltransferase -
  R4703_RS03285 cclA/cilC 616526..617185 (+) 660 WP_000565027.1 A24 family peptidase Machinery gene
  R4703_RS03290 trpA 617157..617933 (-) 777 WP_001126993.1 tryptophan synthase subunit alpha -
  R4703_RS03295 trpB 617926..619149 (-) 1224 WP_000331298.1 tryptophan synthase subunit beta -
  R4703_RS03300 - 619127..619726 (-) 600 WP_000169872.1 phosphoribosylanthranilate isomerase -
  R4703_RS03305 trpC 619713..620480 (-) 768 WP_050200920.1 indole-3-glycerol phosphate synthase TrpC -
  R4703_RS03310 trpD 620477..621481 (-) 1005 WP_000658684.1 anthranilate phosphoribosyltransferase -
  R4703_RS03315 - 621492..622058 (-) 567 WP_000601921.1 aminodeoxychorismate/anthranilate synthase component II -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24855.00 Da        Isoelectric Point: 7.2564

>NTDB_id=895077 R4703_RS03285 WP_000565027.1 616526..617185(+) (cclA/cilC) [Streptococcus pneumoniae strain LYP]
MIDFYFFLVGSILASFLGLVIDRFPEQSIISSVSHCDSCQTRLRPLDLIPILSQVFNRFCCRYCKVRYPVWYALFELGLG
LLFLLYSWELLSLGQVVLITAGLTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCLIIFGKLLLV

Nucleotide


Download         Length: 660 bp        

>NTDB_id=895077 R4703_RS03285 WP_000565027.1 616526..617185(+) (cclA/cilC) [Streptococcus pneumoniae strain LYP]
ATGATTGATTTTTATTTTTTTCTCGTCGGGAGCATTCTCGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGCA
ATCCATTATCAGTTCAGTCAGTCACTGCGATTCCTGTCAGACTCGCTTGCGTCCCTTAGATTTGATTCCGATTCTCTCAC
AGGTCTTCAATCGCTTTTGCTGTCGCTACTGCAAGGTCCGCTATCCTGTCTGGTATGCCCTCTTTGAACTAGGCTTAGGA
CTCCTCTTTCTGCTTTACTCTTGGGAGTTGCTTTCCTTGGGGCAAGTCGTCCTAATCACCGCTGGTTTGACCTTGGGTAT
CTACGACTTTCACCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCACCTAATCCTAATAGCTTCCTCTGGCTGGA
ATCTGGTCATGGTCTCCTTCCTCATACTTGGAATTTTGGCTCATTTTATCGATATCCGCATGGGTGCAGGGGATTTCCTT
TTTTTAGCTTCTTGTGCTCTCGTCTTTAGCGTAACGGAGTTACTGATCTTGATTCAGTTCGCTTCTGCGACGGGTATCCT
GGCCTTTCTCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTACTTGTTTGATTATTTTTG
GTAAGCTACTGCTTGTTTGA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-89)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus pneumoniae Rx1

97.26

100

0.973
  cclA/cilC Streptococcus pneumoniae D39

97.26

100

0.973
  cclA/cilC Streptococcus pneumoniae R6

97.26

100

0.973
  cclA/cilC Streptococcus pneumoniae TIGR4

96.804

100

0.968
  cclA/cilC Streptococcus mitis SK321

91.781

100

0.918
  cclA/cilC Streptococcus mitis NCTC 12261

85.845

100

0.858