Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   R4714_RS04900 Genome accession   NZ_CP137099
Coordinates   882099..882806 (+) Length   235 a.a.
NCBI ID   WP_000166475.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 20824-4     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 877099..887806
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4714_RS04875 argR 877953..878399 (-) 447 WP_001231472.1 arginine repressor -
  R4714_RS04880 argS 878547..880238 (+) 1692 WP_001092739.1 arginine--tRNA ligase -
  R4714_RS04885 - 880553..881110 (-) 558 Protein_914 transposase family protein -
  R4714_RS04890 - 881096..881581 (+) 486 WP_001826677.1 cupin domain-containing protein -
  R4714_RS04895 - 881575..882015 (+) 441 WP_317769884.1 cupin domain-containing protein -
  R4714_RS04900 vicR 882099..882806 (+) 708 WP_000166475.1 response regulator transcription factor Regulator
  R4714_RS04905 pnpS 882807..884138 (+) 1332 WP_000833268.1 two-component system histidine kinase PnpS -
  R4714_RS04910 - 884305..885180 (+) 876 WP_000669493.1 substrate-binding domain-containing protein -
  R4714_RS04915 pstC 885298..886161 (+) 864 WP_000165892.1 phosphate ABC transporter permease subunit PstC -
  R4714_RS04920 pstA 886154..886969 (+) 816 WP_000049768.1 phosphate ABC transporter permease PstA -
  R4714_RS04925 pstB 886971..887723 (+) 753 WP_000536449.1 phosphate ABC transporter ATP-binding protein PstB -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 27230.61 Da        Isoelectric Point: 6.6568

>NTDB_id=895027 R4714_RS04900 WP_000166475.1 882099..882806(+) (vicR) [Streptococcus pneumoniae strain 20824-4]
MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAETEPFDFILLDIMLPQLDGMEVCKRLRAKGVKTPIMMV
SAKSDEFDKVLALELGADDYLTKPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKAPQFIRTIRGYGYKFKEL

Nucleotide


Download         Length: 708 bp        

>NTDB_id=895027 R4714_RS04900 WP_000166475.1 882099..882806(+) (vicR) [Streptococcus pneumoniae strain 20824-4]
ATGACAAAACAAGTCTTATTAGTGGATGATGAAGAACACATTCTGAAATTGCTTGACTACCATTTAAGTAAGGAAGGCTT
TTCTACTCAATTGGTGACAAATGGACGGAAGGCCTTAGCTTTGGCAGAAACAGAACCCTTTGATTTTATCTTGCTTGATA
TCATGTTACCACAATTAGATGGCATGGAAGTTTGTAAGCGGCTGAGAGCCAAAGGCGTCAAAACTCCAATTATGATGGTT
TCTGCGAAAAGTGATGAATTTGATAAGGTTTTGGCCTTGGAATTAGGGGCTGATGACTACCTGACCAAGCCTTTTAGCCC
TAGAGAATTGCTGGCGCGTGTCAAGGCTGTCCTCAGGCGAACTAAAGGAGAACAAGAAGGAGATGATTCAGATAATATCG
CTGACGATTCTTGGCTATTTGGGACCTTGAAAGTATACCCTGAGCGTCATGAAGTCTACAAGGCGAATAAGTTACTGAGT
TTGACCCCAAAAGAATTTGAACTCTTGCTCTATCTTATGAAACATCCCAACATGACACTGACTAGAGAGCGTCTTTTGGA
ACGTATCTGGGGGTATGACTTTGGGCAGGAAACACGTTTGGTGGACGTTCATATTGGTAAGTTGAGGGAAAAAATTGAAG
ACAATCCTAAAGCCCCTCAATTTATTCGAACCATTCGGGGTTATGGTTATAAGTTCAAGGAGTTATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(159-232)

Response regulator receiver domain (Response_reg)

(5-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

48.707

98.723

0.481
  micA Streptococcus pneumoniae Cp1015

47.845

98.723

0.472
  covR Lactococcus lactis subsp. lactis strain DGCC12653

40.773

99.149

0.404
  covR Streptococcus salivarius strain HSISS4

39.744

99.574

0.396