Detailed information
Bioinformatically predicted
Overview
| Name | pilU | Type | Machinery gene |
| Locus tag | R3L09_RS16270 | Genome accession | NZ_CP137064 |
| Coordinates | 3270896..3272014 (+) | Length | 372 a.a. |
| NCBI ID | WP_000347039.1 | Uniprot ID | A0A9P2XLL8 |
| Organism | Acinetobacter baumannii strain SNUBHAB0292 | ||
| Function | mediate the depolymerization of the type IV pilus (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 3243002..3287727 | 3270896..3272014 | within | 0 |
Gene organization within MGE regions
Location: 3243002..3287727
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| R3L09_RS16115 (R3L09_16130) | - | 3243006..3243326 (-) | 321 | WP_000048916.1 | hypothetical protein | - |
| R3L09_RS16120 (R3L09_16135) | - | 3243337..3243588 (-) | 252 | WP_000996060.1 | Cro/CI family transcriptional regulator | - |
| R3L09_RS16125 (R3L09_16140) | - | 3243697..3244461 (+) | 765 | WP_001093662.1 | LexA family transcriptional regulator | - |
| R3L09_RS16130 (R3L09_16145) | - | 3244476..3244691 (+) | 216 | WP_000370477.1 | hypothetical protein | - |
| R3L09_RS16135 (R3L09_16150) | - | 3244742..3245743 (+) | 1002 | WP_000048049.1 | hypothetical protein | - |
| R3L09_RS16140 (R3L09_16155) | - | 3245746..3246249 (+) | 504 | WP_001129671.1 | hypothetical protein | - |
| R3L09_RS16145 (R3L09_16160) | - | 3246458..3246898 (+) | 441 | WP_126064975.1 | hypothetical protein | - |
| R3L09_RS16150 (R3L09_16165) | - | 3246901..3247224 (+) | 324 | WP_032002963.1 | hypothetical protein | - |
| R3L09_RS16155 (R3L09_16170) | - | 3247236..3248357 (+) | 1122 | WP_001207471.1 | ATP-binding protein | - |
| R3L09_RS16160 (R3L09_16175) | - | 3248354..3249355 (+) | 1002 | WP_000698522.1 | hypothetical protein | - |
| R3L09_RS16165 (R3L09_16180) | - | 3249357..3249602 (+) | 246 | WP_000654847.1 | hypothetical protein | - |
| R3L09_RS16170 (R3L09_16185) | - | 3249606..3250016 (+) | 411 | WP_000566309.1 | hypothetical protein | - |
| R3L09_RS16175 (R3L09_16190) | - | 3250009..3250293 (+) | 285 | WP_406627993.1 | hypothetical protein | - |
| R3L09_RS16180 (R3L09_16195) | - | 3250304..3250474 (+) | 171 | WP_000119263.1 | hypothetical protein | - |
| R3L09_RS16185 (R3L09_16200) | - | 3250485..3251153 (-) | 669 | WP_020752531.1 | hypothetical protein | - |
| R3L09_RS16190 (R3L09_16205) | - | 3251153..3252304 (-) | 1152 | WP_000947476.1 | site-specific integrase | - |
| R3L09_RS16200 (R3L09_16215) | ggt | 3253002..3254987 (-) | 1986 | WP_001042923.1 | gamma-glutamyltransferase | - |
| R3L09_RS16205 (R3L09_16220) | - | 3255290..3256813 (-) | 1524 | WP_000857095.1 | DHA2 family efflux MFS transporter permease subunit | - |
| R3L09_RS16210 (R3L09_16225) | - | 3256820..3257971 (-) | 1152 | WP_000128703.1 | EmrA/EmrK family multidrug efflux transporter periplasmic adaptor subunit | - |
| R3L09_RS16215 (R3L09_16230) | - | 3258241..3258738 (-) | 498 | WP_002019577.1 | thioesterase family protein | - |
| R3L09_RS16220 (R3L09_16235) | hemB | 3258881..3259894 (+) | 1014 | WP_000222569.1 | porphobilinogen synthase | - |
| R3L09_RS16225 (R3L09_16240) | - | 3259920..3261035 (+) | 1116 | WP_000546701.1 | FAD-binding oxidoreductase | - |
| R3L09_RS16230 (R3L09_16245) | - | 3261027..3261932 (-) | 906 | WP_001039356.1 | TIGR01777 family oxidoreductase | - |
| R3L09_RS16235 (R3L09_16250) | - | 3262022..3262474 (-) | 453 | WP_000164153.1 | ABZJ_00895 family protein | - |
| R3L09_RS16240 (R3L09_16255) | - | 3262854..3263231 (+) | 378 | WP_001059438.1 | VOC family protein | - |
| R3L09_RS16245 (R3L09_16260) | - | 3263299..3263772 (-) | 474 | WP_000974358.1 | OsmC family protein | - |
| R3L09_RS16250 (R3L09_16265) | - | 3263936..3265204 (+) | 1269 | WP_000116701.1 | exonuclease SbcCD subunit D | - |
| R3L09_RS16255 (R3L09_16270) | - | 3265214..3268810 (+) | 3597 | WP_000698785.1 | AAA family ATPase | - |
| R3L09_RS16260 (R3L09_16275) | - | 3269012..3269704 (-) | 693 | WP_001108512.1 | YggS family pyridoxal phosphate-dependent enzyme | - |
| R3L09_RS16265 (R3L09_16280) | pilT | 3269831..3270868 (+) | 1038 | WP_000355489.1 | type IV pilus twitching motility protein PilT | Machinery gene |
| R3L09_RS16270 (R3L09_16285) | pilU | 3270896..3272014 (+) | 1119 | WP_000347039.1 | PilT/PilU family type 4a pilus ATPase | Machinery gene |
| R3L09_RS16275 (R3L09_16290) | fur | 3272084..3272521 (-) | 438 | WP_001122847.1 | ferric iron uptake transcriptional regulator | - |
| R3L09_RS16280 (R3L09_16295) | - | 3272633..3273031 (+) | 399 | WP_001170994.1 | outer membrane protein assembly factor BamE | - |
| R3L09_RS16285 (R3L09_16300) | - | 3273086..3273409 (-) | 324 | WP_000442587.1 | RnfH family protein | - |
| R3L09_RS16290 (R3L09_16305) | - | 3273409..3274476 (-) | 1068 | WP_002019572.1 | hypothetical protein | - |
| R3L09_RS16295 (R3L09_16310) | - | 3274629..3275084 (-) | 456 | WP_000782976.1 | bacteriohemerythrin | - |
| R3L09_RS16300 (R3L09_16315) | - | 3275337..3276185 (-) | 849 | WP_000336548.1 | class II glutamine amidotransferase | - |
| R3L09_RS16305 (R3L09_16320) | - | 3276294..3277076 (-) | 783 | WP_000890283.1 | GNAT family N-acetyltransferase | - |
| R3L09_RS16310 (R3L09_16325) | argB | 3277197..3278105 (-) | 909 | WP_001135419.1 | acetylglutamate kinase | - |
| R3L09_RS16315 (R3L09_16330) | - | 3278120..3279538 (-) | 1419 | WP_406627994.1 | phosphomannomutase/phosphoglucomutase | - |
| R3L09_RS16320 (R3L09_16335) | dut | 3279738..3280190 (-) | 453 | WP_000868152.1 | dUTP diphosphatase | - |
| R3L09_RS16325 (R3L09_16340) | rep | 3280215..3282254 (-) | 2040 | WP_000093035.1 | DNA helicase Rep | - |
| R3L09_RS16330 (R3L09_16345) | - | 3282448..3283101 (-) | 654 | WP_001202415.1 | OmpA family protein | - |
| R3L09_RS16335 (R3L09_16350) | - | 3283346..3284272 (+) | 927 | WP_000100965.1 | acyltransferase | - |
| R3L09_RS16340 (R3L09_16355) | - | 3284289..3285335 (+) | 1047 | WP_001181639.1 | hypothetical protein | - |
| R3L09_RS16345 (R3L09_16360) | minC | 3285457..3286179 (+) | 723 | WP_000763677.1 | septum site-determining protein MinC | - |
| R3L09_RS16350 (R3L09_16365) | minD | 3286250..3287062 (+) | 813 | WP_001074362.1 | septum site-determining protein MinD | - |
| R3L09_RS16355 (R3L09_16370) | minE | 3287065..3287337 (+) | 273 | WP_000896934.1 | cell division topological specificity factor MinE | - |
| R3L09_RS16360 (R3L09_16375) | - | 3287421..3287708 (+) | 288 | WP_001218560.1 | PA4642 family protein | - |
Sequence
Protein
Download Length: 372 a.a. Molecular weight: 41933.13 Da Isoelectric Point: 6.6944
>NTDB_id=894619 R3L09_RS16270 WP_000347039.1 3270896..3272014(+) (pilU) [Acinetobacter baumannii strain SNUBHAB0292]
MDFNDLLNLMVEKKSSDLFITDGVAPSMKINGQIVPISKNSLSGEVIGQLLHSIMSEKQRREFAETRECNFAIMNREKTA
RFRVSAFQQRDMPGMVLRRIETKIPSIDDLQLPPVLKDLSMTKRGIIIFVGATGTGKSTSLASMISHRNHNSKGHIITIE
DPIEFIHEHAGCIITQREVGIDTDSFEIALKNTLRQAPDVILIGEIRSREVMDYAIGFAETGHLVLATMHANNANQALDR
IIHFFESDRHSQLYMDLSLNLKAMIAQQLIPTPDGNSRRAAIEILINSPLISDYIRKGEIHEIKDLMKRSRELGMQTFDQ
ALFDLYKAGQITYKDALKHADSPNDLRLTIKLADEGPDQLSDGKQHLTFDRQ
MDFNDLLNLMVEKKSSDLFITDGVAPSMKINGQIVPISKNSLSGEVIGQLLHSIMSEKQRREFAETRECNFAIMNREKTA
RFRVSAFQQRDMPGMVLRRIETKIPSIDDLQLPPVLKDLSMTKRGIIIFVGATGTGKSTSLASMISHRNHNSKGHIITIE
DPIEFIHEHAGCIITQREVGIDTDSFEIALKNTLRQAPDVILIGEIRSREVMDYAIGFAETGHLVLATMHANNANQALDR
IIHFFESDRHSQLYMDLSLNLKAMIAQQLIPTPDGNSRRAAIEILINSPLISDYIRKGEIHEIKDLMKRSRELGMQTFDQ
ALFDLYKAGQITYKDALKHADSPNDLRLTIKLADEGPDQLSDGKQHLTFDRQ
Nucleotide
Download Length: 1119 bp
>NTDB_id=894619 R3L09_RS16270 WP_000347039.1 3270896..3272014(+) (pilU) [Acinetobacter baumannii strain SNUBHAB0292]
ATGGATTTTAATGACTTGCTCAACCTGATGGTTGAAAAAAAATCTTCCGATCTCTTTATTACAGATGGCGTTGCGCCCTC
TATGAAGATTAACGGGCAAATTGTTCCAATTTCAAAAAACAGTCTTTCTGGGGAAGTGATTGGTCAACTGTTACATTCCA
TCATGAGTGAAAAACAACGCAGAGAATTTGCAGAAACTCGTGAATGTAACTTTGCCATTATGAACCGTGAAAAAACGGCG
CGTTTTCGTGTCAGTGCTTTTCAGCAGCGCGACATGCCGGGCATGGTACTACGTCGTATTGAAACCAAGATTCCTTCAAT
TGATGACTTGCAGTTACCGCCTGTACTTAAAGATTTATCGATGACCAAACGCGGCATTATTATTTTTGTAGGCGCGACAG
GCACAGGTAAATCTACTTCACTGGCTTCAATGATCAGCCATCGTAACCATAACTCTAAGGGCCATATCATTACCATTGAA
GACCCGATTGAGTTTATTCACGAACATGCAGGTTGCATCATTACTCAGCGTGAAGTCGGGATCGATACCGACTCATTTGA
AATTGCCTTGAAAAATACACTACGACAAGCGCCGGATGTGATCTTAATTGGTGAGATCCGTTCTCGTGAAGTCATGGACT
ACGCGATTGGCTTTGCTGAAACAGGCCATCTTGTATTAGCTACCATGCACGCTAACAACGCCAACCAAGCGCTCGACCGT
ATTATTCACTTTTTTGAAAGTGACCGTCATAGTCAGCTTTACATGGACTTGTCACTTAACTTAAAGGCAATGATTGCGCA
GCAGCTCATTCCAACACCAGATGGTAATTCACGCCGTGCAGCAATTGAGATTTTAATTAACTCACCATTAATTTCAGACT
ACATCCGTAAAGGTGAAATTCATGAAATTAAAGATTTGATGAAACGCTCACGTGAACTTGGTATGCAGACCTTTGACCAA
GCTTTATTTGATTTATATAAAGCTGGTCAAATTACCTACAAAGATGCACTTAAACATGCTGACTCACCGAACGATTTACG
TTTAACCATTAAACTTGCAGATGAAGGTCCTGATCAATTATCAGACGGGAAACAGCATTTAACTTTTGACCGCCAGTAA
ATGGATTTTAATGACTTGCTCAACCTGATGGTTGAAAAAAAATCTTCCGATCTCTTTATTACAGATGGCGTTGCGCCCTC
TATGAAGATTAACGGGCAAATTGTTCCAATTTCAAAAAACAGTCTTTCTGGGGAAGTGATTGGTCAACTGTTACATTCCA
TCATGAGTGAAAAACAACGCAGAGAATTTGCAGAAACTCGTGAATGTAACTTTGCCATTATGAACCGTGAAAAAACGGCG
CGTTTTCGTGTCAGTGCTTTTCAGCAGCGCGACATGCCGGGCATGGTACTACGTCGTATTGAAACCAAGATTCCTTCAAT
TGATGACTTGCAGTTACCGCCTGTACTTAAAGATTTATCGATGACCAAACGCGGCATTATTATTTTTGTAGGCGCGACAG
GCACAGGTAAATCTACTTCACTGGCTTCAATGATCAGCCATCGTAACCATAACTCTAAGGGCCATATCATTACCATTGAA
GACCCGATTGAGTTTATTCACGAACATGCAGGTTGCATCATTACTCAGCGTGAAGTCGGGATCGATACCGACTCATTTGA
AATTGCCTTGAAAAATACACTACGACAAGCGCCGGATGTGATCTTAATTGGTGAGATCCGTTCTCGTGAAGTCATGGACT
ACGCGATTGGCTTTGCTGAAACAGGCCATCTTGTATTAGCTACCATGCACGCTAACAACGCCAACCAAGCGCTCGACCGT
ATTATTCACTTTTTTGAAAGTGACCGTCATAGTCAGCTTTACATGGACTTGTCACTTAACTTAAAGGCAATGATTGCGCA
GCAGCTCATTCCAACACCAGATGGTAATTCACGCCGTGCAGCAATTGAGATTTTAATTAACTCACCATTAATTTCAGACT
ACATCCGTAAAGGTGAAATTCATGAAATTAAAGATTTGATGAAACGCTCACGTGAACTTGGTATGCAGACCTTTGACCAA
GCTTTATTTGATTTATATAAAGCTGGTCAAATTACCTACAAAGATGCACTTAAACATGCTGACTCACCGAACGATTTACG
TTTAACCATTAAACTTGCAGATGAAGGTCCTGATCAATTATCAGACGGGAAACAGCATTTAACTTTTGACCGCCAGTAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| pilU | Acinetobacter baylyi ADP1 |
75.926 |
100 |
0.772 |
| pilU | Pseudomonas stutzeri DSM 10701 |
69.565 |
98.925 |
0.688 |
| pilU | Vibrio cholerae strain A1552 |
53.243 |
99.462 |
0.53 |
| pilT | Deinococcus radiodurans R1 = ATCC 13939 = DSM 20539 |
42.486 |
93.011 |
0.395 |