Detailed information NTG0894443

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: AAVD18_RS16055
• Genome accession: NZ_CP154893
• Coordinates: 3072941..3074137 (-)
• Length: 398 a.a.
• NCBI ID: WP_013354214.1
• Uniprot ID: A0A9P1NK46
• Organism: Bacillus amyloliquefaciens strain Fad 11/2
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 3067941..3079137

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AAVD18_RS16035 (AAVD18_16035)	-	3068903..3069166 (-)	264	WP_013354210.1	hypothetical protein	-
AAVD18_RS16040 (AAVD18_16040)	-	3069345..3070763 (-)	1419	WP_014471292.1	HAMP domain-containing sensor histidine kinase	-
AAVD18_RS16045 (AAVD18_16045)	-	3070760..3071443 (-)	684	WP_013354212.1	response regulator transcription factor	-
AAVD18_RS16050 (AAVD18_16050)	-	3071657..3072568 (+)	912	WP_013354213.1	PepSY domain-containing protein	-
AAVD18_RS16055 (AAVD18_16055)	htrA	3072941..3074137 (-)	1197	WP_013354214.1	S1C family serine protease	Regulator
AAVD18_RS16060 (AAVD18_16060)	vicX	3074224..3075018 (-)	795	WP_013354215.1	MBL fold metallo-hydrolase	Regulator
AAVD18_RS16065 (AAVD18_16065)	yycI	3075034..3075873 (-)	840	WP_014472401.1	two-component system regulatory protein YycI	-
AAVD18_RS16070 (AAVD18_16070)	yycH	3075860..3077218 (-)	1359	WP_013354217.1	two-component system activity regulator YycH	-
AAVD18_RS16075 (AAVD18_16075)	walK	3077208..3079043 (-)	1836	WP_013354218.1	cell wall metabolism sensor histidine kinase WalK	-

Sequence

Protein

• Length: 398 a.a.
• Molecular weight: 42734.68 Da
• Isoelectric Point: 7.4579

>NTDB_id=894443 AAVD18_RS16055 WP_013354214.1 3072941..3074137(-) (htrA) [Bacillus amyloliquefaciens strain Fad 11/2]
MDYNRDDEQYAPEQPRRSKRGYFLSSLIGVIVGAALMGLLLPYWTGGDHGESSKSANQRIGSEQVKTVNVNINDAVTNMV
SRVSDSVVGVLNIQKTDIWGEGGEAGSGSGVIYKKNGNTSYIVTNHHVIEGATEIEISLKDDSRVPAELIGSDRLMDLAV
LKVKTDKIKSVAQFGNSDQVKVGEPVIAIGNPLGLEFAGSVTQGIISGTERAVPVDSNGDGQPDWNAEVLQTDAAINPGN
SGGALMDISGKVVGINSMKIAESAVEGIGLSIPSKLVIPVIQDLEKYGEVRRPFLGIEMKSLTDIASYHWSQTLKLPKGV
KTGAVIMGVDAFSPAGKAGLKKLDVITGFDGHKVNDIVDLRERLYRKKIGDRVKITFYRSGKKKTAEVKLTEADRLQK

Nucleotide

• Length: 1197 bp

>NTDB_id=894443 AAVD18_RS16055 WP_013354214.1 3072941..3074137(-) (htrA) [Bacillus amyloliquefaciens strain Fad 11/2]
GTGGATTATAATCGCGATGATGAACAGTACGCCCCCGAGCAGCCCCGCCGCAGCAAGAGAGGATACTTCCTTTCAAGTCT
GATCGGTGTCATCGTCGGGGCCGCGCTCATGGGTTTACTGCTGCCGTACTGGACAGGCGGAGACCATGGAGAAAGCAGCA
AAAGCGCCAATCAGCGCATCGGCAGCGAACAGGTGAAAACAGTCAACGTAAATATCAATGATGCTGTCACGAATATGGTC
AGCCGTGTATCGGATTCGGTAGTCGGCGTTCTCAATATCCAAAAGACCGATATTTGGGGAGAGGGCGGCGAAGCGGGAAG
CGGGTCCGGCGTCATTTACAAAAAGAACGGAAACACTTCTTATATCGTAACCAATCACCATGTCATTGAAGGTGCGACTG
AAATTGAGATCAGCCTGAAAGATGACTCGCGCGTGCCTGCCGAGCTGATCGGGAGCGACCGTCTGATGGATCTTGCCGTG
TTGAAGGTGAAGACTGATAAAATCAAATCGGTCGCCCAATTCGGCAATTCTGATCAAGTGAAAGTTGGCGAGCCGGTCAT
TGCGATCGGAAACCCGCTCGGACTTGAATTTGCGGGATCGGTGACACAAGGGATCATTTCAGGAACGGAAAGGGCGGTTC
CCGTTGACTCAAACGGCGACGGACAGCCTGATTGGAATGCGGAAGTGCTGCAGACCGACGCCGCGATTAATCCCGGCAAC
AGCGGCGGCGCTTTGATGGATATATCGGGCAAGGTGGTCGGCATCAACTCAATGAAGATTGCTGAATCCGCCGTTGAAGG
AATCGGCCTGTCCATCCCGTCAAAGCTTGTCATTCCCGTTATTCAGGATTTAGAAAAATACGGAGAAGTCAGACGGCCTT
TCCTCGGTATTGAGATGAAATCTTTAACGGATATTGCGAGCTACCATTGGAGCCAGACGCTCAAACTTCCGAAGGGTGTT
AAAACCGGAGCGGTCATTATGGGTGTCGACGCGTTTTCACCGGCTGGAAAAGCAGGCTTGAAAAAGCTCGACGTGATCAC
CGGATTCGACGGACATAAGGTCAATGACATTGTCGATCTCCGTGAGCGTCTGTATCGCAAAAAGATCGGCGACCGTGTCA
AGATCACGTTCTACCGTTCAGGAAAGAAAAAAACAGCGGAAGTCAAACTGACAGAAGCGGATCGATTGCAGAAATAA

Domains

Predicted by InterProScan.

• Trypsin-like peptidase domain (Trypsin_2) (108-255)

• PDZ domain (PDZ_2) (293-390)

• Peptidase family M50 (Peptidase_M50) (320-394)

3D structure

• AlphaFold DB: A0A9P1NK46

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	43.687	99.497	0.435
htrA	Streptococcus gordonii str. Challis substr. CH1	41.602	97.236	0.405
htrA	Streptococcus mitis NCTC 12261	40.26	96.734	0.389