Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrA   Type   Machinery gene
Locus tag   AAYT22_RS00850 Genome accession   NZ_CP154876
Coordinates   158500..161331 (+) Length   943 a.a.
NCBI ID   WP_001152894.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 20155336     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 153500..166331
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AAYT22_RS00825 (AAYT22_00815) - 154069..154632 (+) 564 WP_000166597.1 DNA-3-methyladenine glycosylase I -
  AAYT22_RS00830 (AAYT22_00820) - 154629..155306 (+) 678 WP_000987429.1 CPBP family intramembrane glutamic endopeptidase -
  AAYT22_RS00835 (AAYT22_00825) - 155443..156474 (-) 1032 WP_000255096.1 S66 family peptidase -
  AAYT22_RS00840 (AAYT22_00830) - 156729..157412 (-) 684 WP_000078027.1 DUF1129 domain-containing protein -
  AAYT22_RS00845 (AAYT22_00835) - 157424..158368 (-) 945 WP_000815629.1 magnesium transporter CorA family protein -
  AAYT22_RS00850 (AAYT22_00840) uvrA 158500..161331 (+) 2832 WP_001152894.1 excinuclease ABC subunit UvrA Machinery gene
  AAYT22_RS00855 (AAYT22_00845) - 161324..162385 (+) 1062 WP_001042860.1 M24 family metallopeptidase -
  AAYT22_RS00860 (AAYT22_00850) spx 162517..162915 (+) 399 WP_000591165.1 transcriptional regulator Spx -
  AAYT22_RS00865 (AAYT22_00855) - 162981..163550 (+) 570 WP_000725134.1 SP0191 family lipoprotein -
  AAYT22_RS00870 (AAYT22_00860) - 163637..163903 (+) 267 WP_000507059.1 IreB family regulatory phosphoprotein -
  AAYT22_RS00875 (AAYT22_00865) ruvX 163907..164326 (+) 420 WP_001808830.1 Holliday junction resolvase RuvX -
  AAYT22_RS00880 (AAYT22_00870) - 164342..164647 (+) 306 WP_000017620.1 DUF1292 domain-containing protein -
  AAYT22_RS00885 (AAYT22_00875) - 164953..166203 (+) 1251 WP_000464337.1 folylpolyglutamate synthase/dihydrofolate synthase family protein -

Sequence

Protein


Download         Length: 943 a.a.        Molecular weight: 104110.20 Da        Isoelectric Point: 6.3902

>NTDB_id=893932 AAYT22_RS00850 WP_001152894.1 158500..161331(+) (uvrA) [Streptococcus pneumoniae strain 20155336]
MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGL
SPAISIDQKTTSKNPRSTVGTTTEINDYLRLLYARVGTPYCINGHGAINASSVEQIVDKVLELPERQRLQILAPVIRKKK
GQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRLFDSIEAALRIAEGYVIIDTMDD
SELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCSECDGLGIKLEVDTDLVVPDASKTLHEGALAPWNPISSNYYPNML
EQAMKVFGVAMDKPFEDLSEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVINNIKRRYHETNSDYTRTQMRLYM
NELTCGTCQGYRLNDQALSVRVGGQQGPHIGEISDLSIADHLDLVSQLTLSENEAIIARPILKEIKDRLTFLNNVGLNYL
TLSRSAGTLSGGESQRIRLATQIGSNLSGVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLI
DVGPGAGVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVTGARENNLQNVTARFPLGKFIAVT
GVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHVDRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNE
AKIRGYKKGRFSFNVKGGRCEACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVEFF
QHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYILDEPTTGLHTEDIARLLKVLARFVD
AGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGTIIVTGTPEEVAANEASYTGHYLKGKLHHE

Nucleotide


Download         Length: 2832 bp        

>NTDB_id=893932 AAYT22_RS00850 WP_001152894.1 158500..161331(+) (uvrA) [Streptococcus pneumoniae strain 20155336]
ATGCAAGATAAAATTGTCATTCATGGGGCGCGTGCCCATAATTTAAAAAATATTGATGTGGAGATTCCGCGAGACAAGTT
GGTTGTCGTGACTGGCTTGTCAGGTTCAGGGAAGTCCAGTCTGGCTTTTGATACTCTCTATGCGGAGGGACAACGTCGCT
ATGTAGAGAGTTTGTCTGCCTACGCTCGTCAGTTCTTGGGAAATATGGAAAAACCAGATGTAGATGCCATTGATGGTCTC
AGCCCAGCTATTTCCATCGACCAGAAAACGACTAGTAAAAATCCTCGCTCGACGGTGGGAACGACGACTGAAATCAATGA
CTATCTGCGTCTCCTCTACGCACGTGTGGGGACGCCTTACTGTATCAACGGACATGGAGCTATCAATGCTTCTTCTGTGG
AGCAAATCGTTGATAAGGTTTTGGAGTTACCTGAACGCCAGCGCTTGCAGATCTTGGCTCCTGTCATCCGCAAGAAAAAA
GGCCAACATAAGAGTGTTATCGAGAAGGTTCAGAAAGACGGGTATGTTCGTGTTCGTGTGGATGGGGAAGTCTATGATGT
GACCGAAGTGCCAGAGTTGTCTAAGAGCAAGCAACACAATATCGATGTCGTGGTTGACCGTATTGTTATCAAGGAGGGCA
TTCGTAGCCGTCTCTTTGATTCCATTGAAGCTGCCCTTCGTATCGCAGAAGGTTATGTGATTATCGACACCATGGACGAC
TCTGAGTTGTTGTTCTCTGAGCATTATGCCTGTCCAGTTTGTGGATTTACTGTCCCAGAGTTAGAACCTCGTCTCTTCTC
TTTCAATGCTCCCTTTGGCTCTTGTAGTGAGTGTGACGGCTTGGGGATTAAGCTGGAGGTGGATACTGATTTGGTAGTGC
CAGATGCCAGCAAAACCTTACATGAGGGAGCGCTGGCACCTTGGAATCCTATCTCATCCAACTACTATCCAAACATGTTA
GAGCAGGCCATGAAAGTCTTTGGAGTGGCTATGGATAAGCCTTTTGAGGACCTGTCAGAAGAAGATAAGAACTTGATTCT
CTACGGCTCAGATGGTAAGGAATTCCATTTCCATTATGAAAATGAATTTGGTGGTGTGCGCGATATCGACATTCCGTTTG
AGGGAGTTATCAATAATATCAAACGTCGTTACCATGAAACCAATAGCGATTACACTCGCACTCAGATGCGTCTCTACATG
AATGAGCTGACCTGCGGAACCTGTCAAGGCTATCGTCTCAATGACCAGGCCTTGTCTGTCCGTGTGGGCGGCCAGCAAGG
GCCACATATTGGAGAAATCTCAGACCTGTCTATCGCTGACCACTTGGACTTGGTGAGCCAGTTAACTTTGTCTGAAAATG
AAGCCATCATTGCTCGTCCCATTCTCAAGGAAATCAAGGATCGTTTGACCTTCCTTAATAATGTGGGTCTTAACTATCTA
ACCCTGTCACGTTCAGCAGGAACCCTTTCAGGTGGGGAAAGTCAGCGCATTCGTTTGGCAACCCAGATTGGTTCCAACCT
ATCAGGTGTCCTCTATATCCTAGACGAGCCGTCAATCGGTCTTCACCAGAGGGACAATGACCGCCTGATTGCCAGTCTGA
AAAAGATGCGTGACTTGGGCAATACTCTTATCGTGGTGGAACACGACGAAGATACCATGCGTGAAGCTGATTATCTGATT
GACGTTGGTCCTGGTGCCGGTGTTTTTGGTGGTGAGATTGTTGCAGCAGGTACACCTAAGCAAGTGGCTCGCAACAGCAA
GTCTATCACAGGTCAGTACTTGTCAGGCAAACGTGTCATCCCAGTACCAGAAGAGCGCCGTGTCGGAAATGGTCGTTTTA
TTGAAGTGACAGGAGCGCGTGAGAACAACTTGCAAAATGTCACGGCTCGCTTTCCACTAGGAAAATTTATCGCAGTGACA
GGTGTGTCGGGTTCAGGGAAATCGACTCTAATCAACAGCATTCTCAAAAAAGCCATTGCCCAGAAGCTCAACCGTAATTC
AGACAAACCTGGTAAGTTTAAGACTATTACAGGGATTGAGCATGTCGACCGTTTGATTGATATTGACCAGAGCCCTATCG
GACGGACGCCGAGGTCTAACCCAGCTACCTATACAGGAGTTTTTGACGATATACGTGACCTTTTTGCTCAGACAAATGAA
GCCAAGATTCGAGGCTACAAGAAGGGGCGCTTCAGTTTCAACGTCAAGGGAGGTCGCTGTGAAGCTTGCTCAGGTGACGG
GATTATCAAGATTGAGATGCACTTCTTGCCAGATGTTTATGTGGCTTGTGAAGTTTGCCACGGAACCCGCTATAACAGTG
AAACCCTAGAAGTTCACTACAAGGAAAAGAATATTTCGCAGGTCTTGGATATGACGGTCAACGATGCGGTAGAATTTTTC
CAACACATTCCGAAAATTCAACGCAAACTCCAGACCATCAAGGATGTAGGTCTAGGCTATGTGACCTTGGGACAGCCAGC
TACCACCCTTTCTGGGGGAGAAGCCCAACGTATGAAGTTAGCTAGCGAACTCCACAAACGCTCGACAGGAAAATCTTTCT
ACATTCTGGATGAGCCGACGACAGGGCTTCATACAGAGGACATTGCTCGCCTGCTCAAGGTTTTAGCTCGCTTTGTAGAC
GCCGGCAATACAGTCCTCGTCATCGAGCACAATCTGGATGTTATCAAGACGGCAGACCATATCATTGACTTGGGACCTGA
GGGCGGTGTCGGTGGTGGAACCATCATCGTAACAGGAACTCCAGAAGAAGTAGCTGCTAACGAAGCCAGCTATACAGGAC
ACTATTTGAAAGGAAAGTTACATCATGAATAA

Domains

Predicted by InterProScan.

UvrA interaction domain (UvrA_inter)

(132-238)

ABC transporter (ABC_tran)

(624-860)

UvrA DNA-binding domain (UvrA_DNA-bind)

(288-396)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrA Streptococcus pneumoniae R6

99.682

100

0.997
  uvrA Streptococcus pneumoniae TIGR4

99.682

100

0.997
  uvrA Streptococcus pneumoniae D39

99.682

100

0.997